Cell injury and Premature Neurodegeneration in Focal Malformations of Cortical Development

Alzheimer's Disease and Down Syndrome Rodent Models Exhibit Audiogenic Seizures

(2017) Cara J. Westmark et al.   JOURNAL OF ALZHEIMERS DISEASE

Original article Hemimegalencephaly: foetal tauopathy with mTOR hyperactivation and neuronal lipidosis

(2013) Harvey Sarnat et al.   FOLIA NEUROPATHOLOGICA

Detection of human papillomavirus in human focal cortical dysplasia type IIB

(2012) Julie Chen et al.   ANNALS OF NEUROLOGY

Autophagy activation ameliorates neuronal pathogenesis of FTLD-U mice

(2012) I-Fang Wang et al.   Autophagy

TDP-43 in central nervous system development and function: clues to TDP-43-associated neurodegeneration

(2012) Chantelle F. Sephton et al.   BIOLOGICAL CHEMISTRY

mTOR Signaling in Growth Control and Disease

(2012) Mathieu Laplante et al.   CELL

Death Receptors DR6 and TROY Regulate Brain Vascular Development

(2012) Stephen J. Tam et al.   DEVELOPMENTAL CELL

Elevation of tau protein levels in the cerebrospinal fluid of children with West syndrome

(2012) Hirofumi Inoue et al.   EPILEPSY RESEARCH

Death Receptor 6 Induces Apoptosis Not through Type I or Type II Pathways, but via a Unique Mitochondria-dependent Pathway by Interacting with Bax Protein

(2012) Linlin Zeng et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mammalian target of rapamycin: A valid therapeutic target through the autophagy pathway for alzheimer's disease?

(2012) Zhiyou Cai et al.   JOURNAL OF NEUROSCIENCE RESEARCH

p62/SQSTM1/A170: Physiology and pathology

(2012) Masaaki Komatsu et al.   PHARMACOLOGICAL RESEARCH

Autophagy activators rescue and alleviate pathogenesis of a mouse model with proteinopathies of the TAR DNA-binding protein 43

(2012) I.-F. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Neurofibrillary tangle pathology and Braak staging in chronic epilepsy in relation to traumatic brain injury and hippocampal sclerosis: a post-mortem study

(2011) Maria Thom et al.   BRAIN

ESCRT functions in autophagy and associated disease

(2011) Tor Erik Rusten et al.   CELL CYCLE

Metalloprotease Meprin β Generates Nontoxic N-terminal Amyloid Precursor Protein Fragmentsin Vivo

(2011) Tamara Jefferson et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Amyloid Precursor Protein Revisited

(2011) Qinxi Guo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Crystal Structure of Death Receptor 6 (DR6): A Potential Receptor of the Amyloid Precursor Protein (APP)

(2011) Miriam Kuester et al.   JOURNAL OF MOLECULAR BIOLOGY

Death receptor 6 negatively regulates oligodendrocyte survival, maturation and myelination

(2011) Sha Mi et al.   NATURE MEDICINE

Hyperphosphorylation as a Defense Mechanism to Reduce TDP-43 Aggregation

(2011) Huei-Ying Li et al.   PLoS One

mTOR: A pathogenic signaling pathway in developmental brain malformations

(2011) Peter B. Crino   TRENDS IN MOLECULAR MEDICINE

Evaluation of the innate and adaptive immunity in type I and type II focal cortical dysplasias

(2010) Anand Iyer et al.   EPILEPSIA

Role of TOR signaling in aging and related biological processes in Drosophila melanogaster

(2010) Subhash D. Katewa et al.   EXPERIMENTAL GERONTOLOGY

Physiological significance of selective degradation of p62 by autophagy

(2010) Masaaki Komatsu et al.   FEBS LETTERS

Early Progenitor Cell Marker Expression Distinguishes Type II From Type I Focal Cortical Dysplasias

(2010) Ksenia A. Orlova et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Amyloid Precursor Protein Cleavage-Dependent and -Independent Axonal Degeneration Programs Share a Common Nicotinamide Mononucleotide Adenylyltransferase 1-Sensitive Pathway

(2010) B. P. S. Vohra et al.   JOURNAL OF NEUROSCIENCE

The Human Papillomavirus Type 16 E6 Oncoprotein Activates mTORC1 Signaling and Increases Protein Synthesis

(2010) J. M. Spangle et al.   JOURNAL OF VIROLOGY

An international consensus classification for focal cortical dysplasias

(2010) Ingmar Blümcke et al.   LANCET NEUROLOGY

Tissue plasminogen activator and urokinase plasminogen activator in human epileptogenic pathologies

(2010) A.M. Iyer et al.   NEUROSCIENCE

Computational prediction and analysis of the DR6-NAPP interaction

(2010) Sergei Y. Ponomarev et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Selective degradation of p62 by autophagy

(2010) Yoshinobu Ichimura et al.   Seminars in Immunopathology

Gene Expression Analysis of Tuberous Sclerosis Complex Cortical Tubers Reveals Increased Expression of Adhesion and Inflammatory Factors

(2009) Karin Boer et al.   BRAIN PATHOLOGY

Pi3K-mTOR Signaling and AMOG Expression in Epilepsy-associated Glioneuronal Tumors

(2009) Karin Boer et al.   BRAIN PATHOLOGY

Neuronal caspase-3 signaling: not only cell death

(2009) M D'Amelio et al.   CELL DEATH AND DIFFERENTIATION

Expression patterns of synaptic vesicle protein 2A in focal cortical dysplasia and TSC-cortical tubers

(2009) Sjoukje T. Toering et al.   EPILEPSIA

Rapamycin Rescues TDP-43 Mislocalization and the Associated Low Molecular Mass Neurofilament Instability

(2009) Antonella Caccamo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cellular injury and neuroinflammation in children with chronic intractable epilepsy

(2009) Jieun Choi et al.   Journal of Neuroinflammation

APP binds DR6 to trigger axon pruning and neuron death via distinct caspases

(2009) Anatoly Nikolaev et al.   NATURE

Expression patterns of glial fibrillary acidic protein (GFAP)-delta in epilepsy-associated lesional pathologies

(2009) L. Martinian et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

Rheb controls misfolded protein metabolism by inhibiting aggresome formation and autophagy

(2009) X. Zhou et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cellular localization of metabotropic glutamate receptors in cortical tubers and subependymal giant cell tumors of tuberous sclerosis complex

(2008) K. Boer et al.   NEUROSCIENCE

Akt and CHIP coregulate tau degradation through coordinated interactions

(2008) C. A. Dickey et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Neuro-archaeology: pre-symptomatic architecture and signature of neurological disorders

(2008) Yehezkel Ben-Ari   TRENDS IN NEUROSCIENCES