Tau-Tubulin Kinase 1 Expression, Phosphorylation and Co-Localization with Phospho-Ser422 Tau in the Alzheimer's Disease Brain

The Microtubule-Associated Protein Tau is Also Phosphorylated on Tyrosine

(2017) Thibaud Lebouvier et al.   JOURNAL OF ALZHEIMERS DISEASE

Targeting Phospho-Ser422 by Active Tau Immunotherapy in the THYTau22 Mouse Model: A Suitable Therapeutic Approach

(2012) Nadege Zommer et al.   Current Alzheimer Research

Novel diffusion barrier for axonal retention of Tau in neurons and its failure in neurodegeneration

(2011) Xiaoyu Li et al.   EMBO JOURNAL

Tau-tubulin kinase-1 gene variants are associated with Alzheimer's disease in Han Chinese

(2011) Nan-Nan Yu et al.   NEUROSCIENCE LETTERS

Tau-tubulin kinase 1 enhances prefibrillar tau aggregation and motor neuron degeneration in P301L FTDP-17 tau-mutant mice

(2010) Jiqing Xu et al.   FASEB JOURNAL

Caspase activation precedes and leads to tangles

(2010) Alix de Calignon et al.   NATURE

Genetic variations in tau-tubulin kinase-1 are linked to Alzheimer's disease in a Spanish case-control cohort

(2010) José Luis Vázquez-Higuera et al.   NEUROBIOLOGY OF AGING

Mechanisms of tau-induced neurodegeneration

(2009) Khalid Iqbal et al.   ACTA NEUROPATHOLOGICA

Tau-directed drug discovery for Alzheimer's disease and related tauopathies: A focus on tau assembly inhibitors

(2009) Kurt R. Brunden et al.   EXPERIMENTAL NEUROLOGY

Mediators of tau phosphorylation in the pathogenesis of Alzheimer’s disease

(2009) Diane P Hanger et al.   Expert Review of Neurotherapeutics

Spatial Learning Impairment, Enhanced CDK5/p35 Activity, and Downregulation of NMDA Receptor Expression in Transgenic Mice Expressing Tau-Tubulin Kinase 1

(2009) S. Sato et al.   JOURNAL OF NEUROSCIENCE

Biochemistry of Tau in Alzheimer’s disease and related neurological disorders

(2008) Nicolas Sergeant et al.   Expert Review of Proteomics