Polyethylene glycol-coupled IGF1 delays motor function defects in a mouse model of spinal muscular atrophy with respiratory distress type 1

Similarities between Inherited Demyelinating Neuropathies and Wallerian Degeneration

(2013) Rudolf Martini et al.   AMERICAN JOURNAL OF PATHOLOGY

Intramuscular administration of PEGylated IGF-I improves skeletal muscle regeneration after myotoxic injury

(2013) Karen J.B. Martins et al.   GROWTH HORMONE & IGF RESEARCH

Unknown

(2013) Carlo Rinaldi et al.   MOLECULAR MEDICINE

Fast motor axon loss in SMARD1 does not correspond to morphological and functional alterations of the NMJ

(2013) Frank Krieger et al.   NEUROBIOLOGY OF DISEASE

The neuroinflammatory role of Schwann cells in disease

(2013) Elke Ydens et al.   NEUROBIOLOGY OF DISEASE

Functional improvement in mouse models of familial amyotrophic lateral sclerosis by PEGylated insulin-like growth factor I treatment depends on disease severity

(2012) Stefanie Saenger et al.   Amyotrophic Lateral Sclerosis

Activation of CD4 + T Lymphocytes Improves Wound Healing and Survival After Experimental Myocardial Infarction in Mice

(2012) Ulrich Hofmann et al.   CIRCULATION

Therapeutic potential of PEGylated insulin-like growth factor I for skeletal muscle disease evaluated in two murine models of muscular dystrophy

(2012) Stefan M. Gehrig et al.   GROWTH HORMONE & IGF RESEARCH

Acute injury in the peripheral nervous system triggers an alternative macrophage response

(2012) Elke Ydens et al.   Journal of Neuroinflammation

Unknown

(2012) Michela Murdocca et al.   MOLECULAR MEDICINE

A Collagen α2(I) Mutation Impairs Healing after Experimental Myocardial Infarction

(2011) Ulrich Hofmann et al.   AMERICAN JOURNAL OF PATHOLOGY

Therapeutic effects of PEGylated insulin-like growth factor I in the pmn mouse model of motoneuron disease

(2011) Sibylle Jablonka et al.   EXPERIMENTAL NEUROLOGY

PEGylation enhances the therapeutic potential for insulin-like growth factor I in central nervous system disorders

(2011) S. Saenger et al.   GROWTH HORMONE & IGF RESEARCH

Muscle-specific expression of insulin-like growth factor 1 improves outcome in Lama2Dy-w mice, a model for congenital muscular dystrophy type 1A

(2011) A. Kumar et al.   HUMAN MOLECULAR GENETICS

Increased IGF-1 in muscle modulates the phenotype of severe SMA mice

(2011) Marta Bosch-Marcé et al.   HUMAN MOLECULAR GENETICS

Separation of Fast from Slow Anabolism by Site-specific PEGylation of Insulin-like Growth Factor I (IGF-I)

(2011) Friedrich Metzger et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Peripheral SMN restoration is essential for long-term rescue of a severe spinal muscular atrophy mouse model

(2011) Yimin Hua et al.   NATURE

The Natural Course of Infantile Spinal Muscular Atrophy With Respiratory Distress Type 1 (SMARD1)

(2011) M. Eckart et al.   PEDIATRICS

Macrophages recruited via CCR2 produce insulin-like growth factor-1 to repair acute skeletal muscle injury

(2010) Haiyan Lu et al.   FASEB JOURNAL

Combination of SMN Trans-Splicing and a Neurotrophic Factor Increases the Life Span and Body Mass in a Severe Model of Spinal Muscular Atrophy

(2010) Monir Shababi et al.   HUMAN GENE THERAPY

Axonal prion protein is required for peripheral myelin maintenance

(2010) Juliane Bremer et al.   NATURE NEUROSCIENCE

IGHMBP2 is a ribosome-associated helicase inactive in the neuromuscular disorder distal SMA type 1 (DSMA1)

(2009) Ulf-Peter Guenther et al.   HUMAN MOLECULAR GENETICS

Ciliary neurotrophic factor-induced sprouting preserves motor function in a mouse model of mild spinal muscular atrophy

(2009) Christian M. Simon et al.   HUMAN MOLECULAR GENETICS

Isolation and enrichment of embryonic mouse motoneurons from the lumbar spinal cord of individual mouse embryos

(2009) Stefan Wiese et al.   Nature Protocols

Regulation and localization of ribosomal protein S6 kinase 1 isoforms

(2008) Doyil Kim et al.   GROWTH FACTORS

Delivery of AAV-IGF-1 to the CNS Extends Survival in ALS Mice Through Modification of Aberrant Glial Cell Activity

(2008) James C Dodge et al.   MOLECULAR THERAPY

Intraspinal cord delivery of IGF-I mediated by adeno-associated virus 2 is neuroprotective in a rat model of familial ALS

(2008) Colin K. Franz et al.   NEUROBIOLOGY OF DISEASE