A zebrafish model of CLN2 disease is deficient in tripeptidyl peptidase 1 and displays progressive neurodegeneration accompanied by a reduction in proliferation

Update of the mutation spectrum and clinical correlations of over 360 mutations in eight genes that underlie the neuronal ceroid lipofuscinoses

(2011) Maria Kousi et al.   HUMAN MUTATION

Zebrafish Behavioral Profiling Links Drugs to Biological Targets and Rest/Wake Regulation

(2010) J. Rihel et al.   SCIENCE

The epidemiology of progressive intellectual and neurological deterioration in childhood

(2009) C. Verity et al.   ARCHIVES OF DISEASE IN CHILDHOOD

Complex I deficiency and dopaminergic neuronal cell loss in parkin-deficient zebrafish (Danio rerio)

(2009) L. Flinn et al.   BRAIN

Cerebellar defects in a mouse model of juvenile neuronal ceroid lipofuscinosis

(2009) Jill M. Weimer et al.   BRAIN RESEARCH

Autophagy, immunity and human disease

(2009) Robert J Heath et al.   CURRENT OPINION IN GASTROENTEROLOGY

A novelCLN8mutation in late-infantile-onset neuronal ceroid lipofuscinosis (LINCL) reveals aspects of CLN8 neurobiological function

(2009) Chiara Vantaggiato et al.   HUMAN MUTATION

A novel functional role of iduronate-2-sulfatase in zebrafish early development

(2009) Enrico Moro et al.   MATRIX BIOLOGY

Genetic modulation of apoptotic pathways fails to alter disease course in tripeptidyl-peptidase 1 deficient mice

(2009) Kwi-Hye Kim et al.   NEUROSCIENCE LETTERS

A Primer for Morpholino Use in Zebrafish

(2009) Brent R. Bill et al.   Zebrafish

Zebrafish: an emerging technology forin vivopharmacological assessment to identify potential safety liabilities in early drug discovery

(2008) T P Barros et al.   BRITISH JOURNAL OF PHARMACOLOGY

MPTP and MPP+ target specific aminergic cell populations in larval zebrafish

(2008) V Sallinen et al.   JOURNAL OF NEUROCHEMISTRY

Loss of PINK1 Function Affects Development and Results in Neurodegeneration in Zebrafish

(2008) O. Anichtchik et al.   JOURNAL OF NEUROSCIENCE

The Mannose 6-Phosphate Glycoprotein Proteome

(2008) David E. Sleat et al.   JOURNAL OF PROTEOME RESEARCH

Residual levels of tripeptidyl-peptidase I activity dramatically ameliorate disease in late-infantile neuronal ceroid lipofuscinosis

(2008) David E. Sleat et al.   MOLECULAR GENETICS AND METABOLISM

Intraventricular Enzyme Replacement Improves Disease Phenotypes in a Mouse Model of Late Infantile Neuronal Ceroid Lipofuscinosis

(2008) Michael Chang et al.   MOLECULAR THERAPY