Systemic blockade of P2X3 and P2X2/3 receptors attenuates bone cancer pain behaviour in rats

AF-353, a novel, potent and orally bioavailable P2X3/P2X2/3 receptor antagonist

(2010) Joel R Gever et al.   BRITISH JOURNAL OF PHARMACOLOGY

Endogenous Purinergic Control of Bladder Activity via Presynaptic P2X3 and P2X2/3 Receptors in the Spinal Cord

(2010) T. K. Y. Kaan et al.   JOURNAL OF NEUROSCIENCE

P2X7-Dependent Release of Interleukin-1  and Nociception in the Spinal Cord following Lipopolysaccharide

(2010) A. K. Clark et al.   JOURNAL OF NEUROSCIENCE

Cancer-related pain: a pan-European survey of prevalence, treatment, and patient attitudes

(2009) H. Breivik et al.   ANNALS OF ONCOLOGY

Identification and SAR of novel diaminopyrimidines. Part 2: The discovery of RO-51, a potent and selective, dual P2X3/P2X2/3 antagonist for the treatment of pain

(2009) Alam Jahangir et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Identification and SAR of novel diaminopyrimidines. Part 1: The discovery of RO-4, a dual P2X3/P2X2/3 antagonist for the treatment of pain

(2009) David S. Carter et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

A phenotypically restricted set of primary afferent nerve fibers innervate the bone versus skin: Therapeutic opportunity for treating skeletal pain

(2009) Juan Miguel Jimenez-Andrade et al.   BONE

Rapid isolation and culture of primary microglia from adult mouse spinal cord

(2009) Ping K. Yip et al.   JOURNAL OF NEUROSCIENCE METHODS

MAP kinase and pain

(2008) Ru-Rong Ji et al.   BRAIN RESEARCH REVIEWS

Translational medicine: cancer pain mechanisms and management

(2008) A. Delaney et al.   BRITISH JOURNAL OF ANAESTHESIA

P2X receptors in sensory neurons co-cultured with cancer cells exhibit a decrease in opioid sensitivity

(2008) I. Chizhmakov et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

The management of cancer-related breakthrough pain: Recommendations of a task group of the Science Committee of the Association for Palliative Medicine of Great Britain and Ireland

(2008) Andrew N. Davies et al.   EUROPEAN JOURNAL OF PAIN

A Decrease in Anandamide Signaling Contributes to the Maintenance of Cutaneous Mechanical Hyperalgesia in a Model of Bone Cancer Pain

(2008) I. A. Khasabova et al.   JOURNAL OF NEUROSCIENCE

Investigation into the role of P2X3/P2X2/3 receptors in neuropathic pain following chronic constriction injury in the rat: an electrophysiological study

(2006) Caroline J Sharp et al.   BRITISH JOURNAL OF PHARMACOLOGY