Global dynamic optimization approach to predict activation in metabolic pathways

Evolutionary Tradeoffs between Economy and Effectiveness in Biological Homeostasis Systems

(2013) Pablo Szekely et al.   PLoS Computational Biology

Dynamic optimization of distributed biological systems using robust and efficient numerical techniques

(2012) Carlos Vilas et al.   BMC Systems Biology

Multi-Criteria Optimization of Regulation in Metabolic Networks

(2012) Clara Higuera et al.   PLoS One

Efficiency in Evolutionary Trade-Offs

(2012) E. Noor et al.   SCIENCE

Evolutionary Trade-Offs, Pareto Optimality, and the Geometry of Phenotype Space

(2012) O. Shoval et al.   SCIENCE

Optimal control of metabolic networks with saturable enzyme kinetics

(2011) D.A. Oyarzún   IET Systems Biology

Modelling the optimal timing in metabolic pathway activation—Use of Pontryagin's Maximum Principle and role of the Golden section

(2010) Martin Bartl et al.   BIOSYSTEMS

Multi-objective mixed integer strategy for the optimisation of biological networks

(2010) J.O.H. Sendín et al.   IET Systems Biology

What is flux balance analysis?

(2010) Jeffrey D Orth et al.   NATURE BIOTECHNOLOGY

Sequential Activation of Metabolic Pathways: a Dynamic Optimization Approach

(2009) Diego A. Oyarzún et al.   BULLETIN OF MATHEMATICAL BIOLOGY

Parameter estimation and optimal experimental design

(2008) Julio R. Banga et al.   Essays in Biochemistry

Activity motifs reveal principles of timing in transcriptional control of the yeast metabolic network

(2008) Gal Chechik et al.   NATURE BIOTECHNOLOGY

Dynamic change in promoter activation during lysine biosynthesis in Escherichia coli cells

(2007) Jianhong Ou et al.   Molecular BioSystems