A mathematical model of the unfolded protein stress response reveals the decision mechanism for recovery, adaptation and apoptosis

Proteome analysis of tunicamycin-induced ER stress

(2012) Vibeke Hervik Bull et al.   ELECTROPHORESIS

A review of the mammalian unfolded protein response

(2011) Anirikh Chakrabarti et al.   BIOTECHNOLOGY AND BIOENGINEERING

Structure of the Ire1 autophosphorylation complex and implications for the unfolded protein response

(2011) Maruf M U Ali et al.   EMBO JOURNAL

Putting the brakes on the unfolded protein response: Figure 1.

(2011) Frank Sicheri et al.   JOURNAL OF CELL BIOLOGY

Attenuation of yeast UPR is essential for survival and is mediated byIRE1kinase

(2011) Aditi Chawla et al.   JOURNAL OF CELL BIOLOGY

Homeostatic adaptation to endoplasmic reticulum stress depends on Ire1 kinase activity

(2011) Claudia Rubio et al.   JOURNAL OF CELL BIOLOGY

Practical limits for reverse engineering of dynamical systems: a statistical analysis of sensitivity and parameter inferability in systems biology models

(2011) Kamil Erguler et al.   Molecular BioSystems

Integrating the mechanisms of apoptosis induced by endoplasmic reticulum stress

(2011) Ira Tabas et al.   NATURE CELL BIOLOGY

Unfolded Proteins Are Ire1-Activating Ligands That Directly Induce the Unfolded Protein Response

(2011) B. M. Gardner et al.   SCIENCE

BioModels Database: An enhanced, curated and annotated resource for published quantitative kinetic models

(2010) Chen Li et al.   BMC Systems Biology

Endoplasmic reticulum stress-sensing mechanisms in yeast and mammalian cells

(2010) Yukio Kimata et al.   CURRENT OPINION IN CELL BIOLOGY

Endoplasmic reticulum stress as a progression factor for kidney injury

(2010) Reiko Inagi   CURRENT OPINION IN PHARMACOLOGY

Preconditioning with Endoplasmic Reticulum Stress Mitigates Retinal Endothelial Inflammation via Activation of X-box Binding Protein 1

(2010) Jingming Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Wolfram syndrome 1 gene negatively regulates ER stress signaling in rodent and human cells

(2010) Sonya G. Fonseca et al.   JOURNAL OF CLINICAL INVESTIGATION

Modeling the endoplasmic reticulum unfolded protein response

(2010) Amos Onn et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Mammalian endoplasmic reticulum stress sensor IRE1 signals by dynamic clustering

(2010) H. Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

BiP Binding to the ER-Stress Sensor Ire1 Tunes the Homeostatic Behavior of the Unfolded Protein Response

(2010) David Pincus et al.   PLOS BIOLOGY

ER and aging—Protein folding and the ER stress response

(2009) Nirinjini Naidoo   AGEING RESEARCH REVIEWS

Computational Analysis of Dynamical Responses to the Intrinsic Pathway of Programmed Cell Death

(2009) Tongli Zhang et al.   BIOPHYSICAL JOURNAL

IRE1α Kinase Activation Modes Control Alternate Endoribonuclease Outputs to Determine Divergent Cell Fates

(2009) Dan Han et al.   CELL

Translation Attenuation through eIF2α Phosphorylation Prevents Oxidative Stress and Maintains the Differentiated State in β Cells

(2009) Sung Hoon Back et al.   Cell Metabolism

Activation of mammalian IRE1α upon ER stress depends on dissociation of BiP rather than on direct interaction with unfolded proteins

(2009) Daisuke Oikawa et al.   EXPERIMENTAL CELL RESEARCH

Stress-sensing mechanisms in the unfolded protein response: similarities and differences between yeast and mammals

(2009) K. Kohno   JOURNAL OF BIOCHEMISTRY

Regulation of Endoplasmic Reticulum Stress-induced Cell Death by ATF4 in Neuroectodermal Tumor Cells

(2009) Jane L. Armstrong et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Endoplasmic reticulum stress in proteinuric kidney disease

(2009) Andrey V. Cybulsky   KIDNEY INTERNATIONAL

Fine-Tuning of the Unfolded Protein Response: Assembling the IRE1α Interactome

(2009) Claudio Hetz et al.   MOLECULAR CELL

Rationalizing translation attenuation in the network architecture of the unfolded protein response

(2008) A. Trusina et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Inherited diseases of the glomerular basement membrane

(2007) Marie Claire Gubler   Nature clinical practice. Nephrology