A cross-species analysis method to analyze animal models' similarity to human's disease state

New approaches to the representation and analysis of phenotype knowledge in human diseases and their animal models

(2011) P. N. Schofield et al.   Briefings in Functional Genomics

Large scale comparison of global gene expression patterns in human and mouse

(2011) Xiangqun Zheng-Bradley et al.   GENOME BIOLOGY

The similarity of gene expression between human and mouse tissues

(2011) Robin D Dowell   GENOME BIOLOGY

Celastrol regulates multiple nuclear transcription factors belonging to HSP90's clients in a dose- and cell type-dependent way

(2010) Denghai Zhang et al.   CELL STRESS & CHAPERONES

Aldose Reductase and Cardiovascular Diseases, Creating Human-Like Diabetic Complications in an Experimental Model

(2010) Ravichandran Ramasamy et al.   CIRCULATION RESEARCH

Histone deacetylase inhibitor vorinostat suppresses the growth of uterine sarcomas in vitro and in vivo

(2010) Andelko Hrzenjak et al.   Molecular Cancer

Divergence of human and mouse brain transcriptome highlights Alzheimer disease pathways

(2010) Jeremy A. Miller et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Development of a mouse model for sporadic and metastatic colon tumors and its use in assessing drug treatment

(2010) K. E. Hung et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Discovery of drug mode of action and drug repositioning from transcriptional responses

(2010) F. Iorio et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The protective effect of genistein postconditioning on hypoxia/reoxygenation-induced injury in human gastric epithelial cells

(2009) Yu Li et al.   ACTA PHARMACOLOGICA SINICA

Prazosin for the Treatment of Behavioral Symptoms in Patients With Alzheimer Disease With Agitation and Aggression

(2009) Lucy Y. Wang et al.   AMERICAN JOURNAL OF GERIATRIC PSYCHIATRY

Constitutively Active Akt Inhibits Trafficking of Amyloid Precursor Protein and Amyloid Precursor Protein Metabolites through Feedback Inhibition of Phosphoinositide 3-Kinase†

(2009) Diana W. Shineman et al.   BIOCHEMISTRY

Heat shock protein 90: translation from cancer to Alzheimer's disease treatment?

(2009) Wenjie Luo et al.   BMC NEUROSCIENCE

Towards Retinoid Therapy for Alzheimers Disease

(2009) K. Shudo et al.   Current Alzheimer Research

Zebrafish: A Complete Animal Model for In Vivo Drug Discovery and Development

(2009) Chiranjib Chakraborty et al.   CURRENT DRUG METABOLISM

Valproic acid (VPA), a histone deacetylase (HDAC) inhibitor, diminishes lymphoproliferation in the Fas -deficient MRL/lpr−/− murine model of autoimmune lymphoproliferative syndrome (ALPS)

(2009) Kennichi C. Dowdell et al.   EXPERIMENTAL HEMATOLOGY

Essential Role of the 90-Kilodalton Heat Shock Protein in Mediating Nongenomic Estrogen Signaling in Coronary Artery Smooth Muscle

(2009) G. Han et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Docosahexaenoic Acid Inhibits Superoxide Dismutase 1 Gene Transcription in Human Cancer Cells: The Involvement of Peroxisome Proliferator-Activated Receptor   and Hypoxia-Inducible Factor-2  Signaling

(2009) E. R. Tuller et al.   MOLECULAR PHARMACOLOGY

Neuroprotective effects of brain-derived neurotrophic factor in rodent and primate models of Alzheimer's disease

(2009) Alan H Nagahara et al.   NATURE MEDICINE

The Role of Hypoxia in 2-Butoxyethanol–Induced Hemangiosarcoma

(2009) Daphna Laifenfeld et al.   TOXICOLOGICAL SCIENCES

Nitrate Enhances the Survival of Mycobacterium tuberculosis during Inhibition of Respiration

(2008) C. D. Sohaskey   JOURNAL OF BACTERIOLOGY

Gene expression module-based chemical function similarity search

(2008) Y. Li et al.   NUCLEIC ACIDS RESEARCH