Article
Public, Environmental & Occupational Health
Katja Troberg, Pernilla Isendahl, Marianne Alanko Blome, Disa Dahlman, Anders Hakansson
Summary: This study investigates participant characteristics and factors associated with naloxone refill and overdose reversal. The findings show that participants trained at needle exchange programs, with previous overdose experiences, or who had used sedatives were more likely to report overdose reversals. Most overdoses occurred in private settings, with the victim being a friend or acquaintance of the rescuer.
FRONTIERS IN PUBLIC HEALTH
(2022)
Article
Substance Abuse
Suzanne Nielsen, Nick Scott, Tom Tidhar, Maria del Mar Quiroga, Simon Lenton, Paul Dietze
Summary: The study indicates that scaling up the provision of take-home naloxone to 90% of individuals prescribed daily doses of >= 50 mg of oral morphine equivalents by 2030 in Australia would be cost-effective and could save more than 650 lives.
Article
Health Policy & Services
Stella M. Resko, Emily Pasman, Danielle L. Hicks, Guijin Lee, Jennifer D. Ellis, Sydney O'Shay, Suzanne Brown, Elizabeth Agius
Summary: Providing family members of individuals with opioid use disorders (OUD) naloxone is a cost-effective way to prevent overdose deaths. However, misconceptions and negative attitudes towards naloxone hinder family engagement. This study examines factors associated with knowledge and attitudes toward naloxone among adults with close family members who misused opioids.
JOURNAL OF COMMUNITY HEALTH
(2023)
Article
Health Care Sciences & Services
Bradley D. Stein, Rosanna Smart, Christopher M. Jones, Flora Sheng, David Powell, Mark Sorbero
Summary: This study examined naloxone co-prescribing in long-term opioid therapy episodes and found that the rate of co-prescribing is low overall, with variations based on different individual and community characteristics.
JOURNAL OF GENERAL INTERNAL MEDICINE
(2021)
Article
Public, Environmental & Occupational Health
Susannah Slocum, Jenny E. Ozga, Rebecca Joyce, Alexander Y. Walley, Robin A. Pollini
Summary: Despite high levels of pharmacy naloxone access in Massachusetts, few bystanders in our study had attempted to obtain naloxone under the NSO. Low perceived risk of overdose, misinformation, stigma, and confidentiality were important barriers to pharmacy naloxone uptake, all of which are amenable to intervention. Support groups provided a setting for addressing stigma and misinformation and provided a discreet and comfortable setting for naloxone access.
Article
Substance Abuse
Elizabeth N. Kinnard, Ricky N. Bluthenthal, Alex H. Kral, Lynn D. Wenger, Barrot H. Lambdin
Summary: The study revealed that people of color and individuals experiencing homelessness were less likely to receive naloxone in the past six months, while those who used opioids more frequently and witnessed overdoses were more likely to receive naloxone.
DRUG AND ALCOHOL DEPENDENCE
(2021)
Article
Substance Abuse
Lauren Dayton, Alyona Mazhnaya, Kristin E. Schneider, Xiangrong Kong, Abigail Winiker, Melissa Davey-Rothwell, Karin E. Tobin, Carl A. Latkin
Summary: This study examined trends in overdose behaviors in Baltimore, Maryland from 2017 to 2019. Most participants were male, Black, experienced homelessness, and were on average 45 years old. Witnessed overdose marginally increased, while personally experiencing overdose did not significantly change over time. Most participants had or had been prescribed naloxone, and both access to and carrying naloxone increased over time.
DRUG AND ALCOHOL DEPENDENCE
(2021)
Article
Public, Environmental & Occupational Health
Christopher Dunphy, Kun Zhang, Gery P. Guy, Christopher M. Jones
Summary: The rate of commercially insured individuals being co-dispensed naloxone increased between 2015 and 2018 across all population subgroups. Despite increases in naloxone dispensing from 2015 to 2018, the provision of naloxone to the commercially insured population remains low. Opportunities remain to increase the supply of naloxone to at-risk populations.
PREVENTIVE MEDICINE
(2021)
Article
Substance Abuse
Alex S. Bennett, Tarlie Townsend, Luther Elliott
Summary: The study found that during the COVID-19 pandemic, people who use illicit opioids were significantly affected, facing difficulties such as obtaining food and mental health issues. The research showed that some participants experienced challenges related to drug supply, but overall, these difficulties diminished as the pandemic progressed, and the number of overdose events decreased.
INTERNATIONAL JOURNAL OF DRUG POLICY
(2022)
Review
Public, Environmental & Occupational Health
Amina Moustaqim-Barrette, Damon Dhillon, Justin Ng, Kristen Sundvick, Farihah Ali, Tara Elton-Marshall, Pamela Leece, Katherine Rittenbach, Max Ferguson, Jane A. Buxton
Summary: Naloxone programs, especially 'take-home naloxone', have emerged as a key intervention in reducing opioid overdose deaths. Existing systematic reviews and best practice guidelines mainly focus on naloxone effectiveness, safety, provision feasibility, dosing and routes of administration, overdose response after naloxone administration, cost-effectiveness, training and education, as well as recommendations for policy, practice, and knowledge gaps.
Article
Substance Abuse
Kristin E. Schneider, Glenna J. Urquhart, Saba Rouhani, Ju Nyeong Park, Miles Morris, Sean T. Allen, Susan G. Sherman
Summary: Despite some opioid users having access to naloxone, a significant proportion still perceive difficulty in obtaining it in the community. Many participants were not aware of multiple locations where they could obtain naloxone, with the health department being the most commonly identified source. Identifying multiple sources of naloxone was associated with easier access perception.
HARM REDUCTION JOURNAL
(2021)
Review
Substance Abuse
Rosanna Smart, Bryce Pardo, Corey S. Davis
Summary: The existing literature on naloxone access laws in the United States supports beneficial effects for increased naloxone distribution, but provides inconclusive evidence for reduced fatal opioid overdose. Mixed findings may reflect variation in the laws' design and implementation, confounding effects of concurrent policy adoption, or differential effectiveness in light of changing opioid environments.
Article
Immunology
Heather Bradley, Eric W. Hall, Alice Asher, Nathan W. Furukawa, Christopher M. Jones, Jalissa Shealey, Kate Buchacz, Senad Handanagic, Nicole Crepaz, Eli S. Rosenberg
Summary: The study estimated that about 3.69 million people injected drugs in the United States in 2018, accounting for 1.46% of the adult population. Injection drug use prevalence was highest among males (2.1%), non-Hispanic Whites (1.8%), and adults aged 18-39 years (1.8%).
CLINICAL INFECTIOUS DISEASES
(2023)
Article
Health Care Sciences & Services
Ingrid A. Binswanger, Deborah Rinehart, Shane R. Mueller, Komal J. Narwaney, Melanie Stowell, Nicole Wagner, Stan Xu, Rebecca Hanratty, Josh Blum, Kevin McVaney, Jason M. Glanz
Summary: Co-dispensing naloxone with opioids effectively increased naloxone receipt and knowledge but did not increase self-reported risk behavior.
JOURNAL OF GENERAL INTERNAL MEDICINE
(2022)
Article
Substance Abuse
Anna Palmer, Peter Higgs, Nick Scott, Paul Agius, Lisa Maher, Paul Dietze
Summary: The study estimated the prevalence of and risk factors associated with concurrent injection of multiple substances among people who inject drugs in Melbourne, Australia. One-third of participants reported co-injecting substances, with male sex and more frequent injection associated with co-injection. The findings suggest that co-injection of multiple substances is common and linked to various risk factors.
Article
Substance Abuse
Kristin E. Schneider, Noa Krawczyk, Ziming Xuan, Renee M. Johnson
DRUG AND ALCOHOL DEPENDENCE
(2018)
Article
Substance Abuse
Jonathan K. Noel, Ziming Xuan, Thomas F. Babor
SUBSTANCE USE & MISUSE
(2018)
Article
Substance Abuse
Thomas K. Greenfield, Won K. Cook, Katherine J. Karriker-Jaffe, Deidre Patterson, William C. Kerr, Ziming Xuan, Timothy S. Naimi
ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH
(2019)
Article
Substance Abuse
Traci Hong, Jiaxi Wu, Derry Wijaya, Ziming Xuan, Jessica L. Fetterman
Summary: The study found that the public has insufficient awareness of the cardiovascular health risks of vaping. Adolescents and females are more likely to mention JUUL and cardiovascular terms with humor, downplaying the severity of tobacco as a major risk factor for cardiovascular disease.
TOBACCO INDUCED DISEASES
(2021)
Article
Medicine, General & Internal
Christopher W. Shanahan, Olivia Reding, Inga Holmdahl, Julia Keosaian, Ziming Xuan, David McAneny, Marc Larochelle, Jane Liebschutz
Summary: Surgeons prescribed an average of 242 total morphine equivalent dose (MED) per patient postoperatively, while patients used an average of 116 total MED. Older age, higher preoperative pain levels, and history of opioid misuse were associated with higher postoperative opioid consumption among patients.
Article
Medicine, General & Internal
Jasmin Choi, Deepika Bahl, Monika Arora, Ziming Xuan
Summary: This study found a significant increase in self-reported STI prevalence among married couples in India over the past decade, with a notable treatment seeking gap.
Article
Substance Abuse
Lynsie R. R. Ranker, Craig S. S. Ross, Abby E. E. Rudolph, Jennifer Weuve, Ziming Xuan
Summary: This study analyzed the long-term trajectories of alcohol use in youth and found diverse patterns of drinking behaviors. Early initiation of drinking was associated with higher odds of membership in high-frequency and earlier-onset trajectory groups. The study also identified differences in trajectory membership based on gender, racial identity, parental factors, and household characteristics.
Article
Substance Abuse
Ziming Xuan, William DeJong, Michael Siegel, Thomas F. Babor
ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH
(2017)
Article
Public, Environmental & Occupational Health
Michael Siegel, Ziming Xuan, Craig S. Ross, Sandro Galea, Bindu Kalesan, Eric Fleegler, Kristin A. Goss
AMERICAN JOURNAL OF PUBLIC HEALTH
(2017)
Article
Public, Environmental & Occupational Health
Victoria M. Smith, Michael Siegel, Ziming Xuan, Craig S. Ross, Sandro Galea, Bindu Kalesan, Eric Fleegler, Kristin A. Goss
AMERICAN JOURNAL OF PREVENTIVE MEDICINE
(2017)
Article
Medicine, General & Internal
Carolina Diez, Rachel P. Kurland, Emily F. Rothman, Megan Bair-Merritt, Eric Fleegler, Ziming Xuan, Sandro Galea, Craig S. Ross, Bindu Kalesan, Kristin A. Goss, Michael Siegel
ANNALS OF INTERNAL MEDICINE
(2017)
Article
Medicine, General & Internal
Jhumka Gupta, Kathryn L. Falb, Oriana Ponta, Ziming Xuan, Paola Abril Campos, Annabel Arellano Gomez, Jimena Valades, Gisele Carino, Claudia Diaz Olavarrieta
Article
Public, Environmental & Occupational Health
Michael Siegel, Molly Pahn, Ziming Xuan, Craig S. Ross, Sandro Galea, Bindu Kalesan, Eric Fleegler, Kristin A. Goss
AMERICAN JOURNAL OF PUBLIC HEALTH
(2017)
Article
Public, Environmental & Occupational Health
Bindu Kalesan, Chandana Adhikarla, Joyce C. Pressley, Jeffrey A. Fagan, Ziming Xuan, Michael B. Siegel, Sandro Galea
AMERICAN JOURNAL OF EPIDEMIOLOGY
(2017)
Article
Substance Abuse
Timothy S. Naimi, Jason G. Blanchette, Ziming Xuan, Francis J. Chaloupka
JOURNAL OF STUDIES ON ALCOHOL AND DRUGS
(2018)