Article
Nutrition & Dietetics
Pilar Sanchis, Rafael Maria Prieto, Jadwiga Konieczna, Felix Grases, Itziar Abete, Jordi Salas-Salvado, Vicente Martin, Miguel Ruiz-Canela, Nancy Babio, Jesus Francisco Garcia-Gavilan, Albert Goday, Antonia Costa-Bauza, Jose Alfredo Martinez, Dora Romaguera
Summary: The main objective of this study was to examine the relationship between dietary phytate intake and bone mineral density (BMD) in a Mediterranean population of postmenopausal women. The results showed that phytate intake was positively associated with BMD in Mediterranean postmenopausal women, indicating a potential protective effect on bone. However, further large-scale, long-term, and randomized prospective clinical studies are needed to assess the potential benefits of phytate consumption on BMD in postmenopausal women.
Article
Nutrition & Dietetics
Patricia Paula da Fonseca Grili, Camila Vilarinho Vidigal, Geise Ferreira da Cruz, Ben-Hur Albergaria, Jose Luiz Marques-Rocha, Taisa Sabrina Silva Pereira, Valdete Regina Guandalini
Summary: This study aimed to identify nutrient patterns (NPs) and their association with bone mineral density (BMD) categories in postmenopausal women. The results showed that lower consumption of NP1 and NP2 was associated with an increased risk of osteopenia, but not osteoporosis.
Article
Endocrinology & Metabolism
Katherine W. Reeves, Gabriela Vieyra, Nydjie P. Grimes, Jaymie Meliker, Rebecca D. Jackson, Jean Wactawski-Wende, Robert Wallace, R. Thomas Zoeller, Carol Bigelow, Susan E. Hankinson, JoAnn E. Manson, Jane A. Cauley, Antonia M. Calafat
Summary: The study found that certain phthalate biomarkers were associated with greater percentage decreases in total hip and femoral neck bone mineral density (BMD), suggesting that phthalate exposure may have clinically significant effects on BMD and potentially increase fracture risk.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
(2021)
Review
Pharmacology & Pharmacy
Yi Chen, Jun Zhu, Yiqin Zhou, Jinhui Peng, Bo Wang
Summary: Denosumab is a promising antiresorptive agent in postmenopausal women with osteoporosis or low bone mineral density, showing greater increase in bone mineral density and reduced fracture risk compared to placebo, without excess risks of adverse events.
FRONTIERS IN PHARMACOLOGY
(2021)
Article
Orthopedics
Hao Chai, Jirong Ge, Li Li, Jianyang Li, Yunjin Ye
Summary: This study revealed that Chinese postmenopausal women with osteoporosis had a higher prevalence of hypertension, indicating a significant association between hypertension and osteoporosis.
BMC MUSCULOSKELETAL DISORDERS
(2021)
Article
Biochemistry & Molecular Biology
Graziamaria Corbi, Vincenzo Nobile, Valeria Conti, Alessandro Cannavo, Vincenzo Sorrenti, Alessandro Medoro, Giovanni Scapagnini, Sergio Davinelli
Summary: This study aimed to evaluate the effects of equol and resveratrol on bone turnover biomarkers in postmenopausal women. The results showed that the combination of equol and resveratrol significantly improved bone turnover biomarkers and increased bone mineral density, suggesting a potential approach to prevent age-related bone loss in postmenopausal women.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Endocrinology & Metabolism
Julien Paccou, Sammy Badr, Daniela Lombardo, Huda Khizindar, Valerie Deken, Stefan Ruschke, Dimitrios C. Karampinos, Anne Cotten, Bernard Cortet
Summary: This study aimed to determine the association between proton density fat fraction (PDFF) and fractures. A case-control study was conducted on postmenopausal women, and it was found that MRI-based measurement of proximal femur PDFF can discriminate between postmenopausal women with and without clinical vertebral fractures, independent of age, CCI, and BMD.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
(2023)
Article
Nutrition & Dietetics
Kelsey M. Mangano, Sabrina E. Noel, Bess Dawson-Hughes, Katherine L. Tucker
Summary: This study found no significant association between dietary vitamin C and BMD, but low plasma vitamin C was associated with lower hip BMD, particularly among postmenopausal women without estrogen therapy.
JOURNAL OF NUTRITION
(2021)
Article
Nutrition & Dietetics
Patricia Paula da Fonseca Grili, Camila Vilarinho Vidigal, Geise Ferreira da Cruz, Ben Hur Albergaria, Jose Luiz Marques-Rocha, Taisa Sabrina Silva Pereira, Valdete Regina Guandalini
Summary: This study evaluated the association between dietary selenium consumption and bone mineral density in postmenopausal women. The results showed that postmenopausal women with higher selenium consumption were less likely to have osteoporosis.
FRONTIERS IN NUTRITION
(2022)
Article
Endocrinology & Metabolism
Albert Shieh, Kristine M. Ruppert, Gail A. Greendale, Yinjuan Lian, Jane A. Cauley, Sherri-Ann Burnett-Bowie, Carrie Karvonen-Guttierez, Arun S. Karlamangla
Summary: Years since the final menstrual period (FMP) is more strongly associated with postmenopausal bone mineral density (BMD) than chronological age, and earlier menopause is associated with more fractures.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
(2022)
Article
Medicine, General & Internal
Wei Wang, Zhe Yuan Chen, Fen Yan Lv, Mei Tu, Xiu Li Guo
Summary: This study evaluates the correlation of serum HDL-c and apolipoprotein A1 (APOA1) with bone metabolism in Chinese postmenopausal women with type 2 diabetes mellitus (T2DM). The results show that APOA1 is more strongly associated with bone metabolism compared to HDL-c.
FRONTIERS IN MEDICINE
(2023)
Article
Endocrinology & Metabolism
Xiaojuan Xu, Manna Zhang, Zhaoliang Fei, Hui Sheng, Shen Qu, Ran Cui
Summary: The study found a significant association between lower extremity arterial calcification and osteoporosis in female patients with type 2 diabetes, but not in male patients. This suggests a potential gender difference in the relationship between arterial calcification and osteoporosis in individuals with type 2 diabetes.
OSTEOPOROSIS INTERNATIONAL
(2021)
Article
Orthopedics
Weibin Du, Zhenwei Wang, Yi Dong, Jintao Hu, Xiaoping Chen
Summary: This study aimed to examine the relationship between fibrinogen and bone mineral density (BMD) in postmenopausal women. The findings of this cross-sectional analysis showed a negative association between fibrinogen levels and total BMD in most postmenopausal women, with a lack of significant correlation in Non-Hispanic Blacks.
JOURNAL OF ORTHOPAEDIC SURGERY AND RESEARCH
(2023)
Article
Endocrinology & Metabolism
Wei Wang, Rong Huang, Ping Tai Tang, Mei Tu, Xiu Li Guo
Summary: This study found that perirenal fat thickness is significantly associated with bone turnover markers, bone mineral density, and osteoporosis, suggesting that perirenal fat may play an important role in bone metabolism.
FRONTIERS IN ENDOCRINOLOGY
(2022)
Article
Orthopedics
Jiemei Gu, Hao Zhang, Qingyun Xue, Li Wang, Zhifeng Cheng, Yawei Zhang, Qifu Li, Lingqing Yuan, Yukun Li, Jin Dong, Yanan Huo, Xin Tang, Ling Hu, Xinjia Wang, Fei Hua, Lin Shen, Jinluo Cheng, Huimin Zhou, Youjia Xu, Tao Yang, Chuansuo Wang, Jin Xu, Jie Shen, Ying Zhang, Xiaomei Zhang, Dun Hong, Xiaoling Guan, Xinhua Xiao, Guang Wang, Yonghua Liu, Liujun Fu, Jianting Chen, Xigao Cheng, Yue Ding, Lijun Liu, Qi Yao, Xinchao Zhang, Lixin Li, Panjun Zhang, Chunying Deng, Chengyan Jiang, Li You, Kai Wang, Shimin Zhang, Jianzhong Xiao, Wei Liu, Xiaohong Du, Xianwen Shang, Tianrong Pan, Chen Lei, Shuren Guo, Zhenlin Zhang
Summary: This study assessed the efficacy, safety, pharmacokinetics, and immunogenicity of a denosumab biosimilar (LY06006) in Chinese postmenopausal women with osteoporosis. The results showed that LY06006 significantly increased bone mineral density and reduced bone resorption. The safety and tolerability of LY06006 were comparable to the reference drug Prolia(R).
JOURNAL OF ORTHOPAEDIC TRANSLATION
(2023)
Article
Orthopedics
Fatima Zahrae Taik, Samia Karkouri, Latifa Tahiri, Ilham Aachari, Jihad Moulay Berkchi, Ihsane Hmamouchi, Redouane Abouqal, Hanan Rkain, Fadoua Allali
Summary: This study showed that standardized therapeutic KT for shoulder pain was not superior to sham KT application in improving pain and disabilities in patients with RCT.
BMC MUSCULOSKELETAL DISORDERS
(2022)
Review
Biochemistry & Molecular Biology
Fatima Sfifou, Mounir Ouzir, El Mehdi Hakkou, Majdouline Obtel, Hassan Errihani, Abderrahmane Al Bouzidi, Redouane Abouqal, Abdessamad El Ouahabi, Nadia Cherradi
Summary: The study found an association between the expression of IDH1 in diffuse gliomas and clinical characteristics, while no clear correlation was observed between the expression of HIF-1alpha and TP53 with clinical features. Furthermore, IDH1 was more frequently expressed in females, and there was no clear association between IDH1 and HIF-1alpha expression.
JOURNAL OF CHEMICAL NEUROANATOMY
(2022)
Article
Psychiatry
Ali Ikrou, Sam Gnanapragasam, Redouane Abouqal, Jihane Belayachi
Summary: This study examined the psychological health status of Moroccan nursing and technique health students and found that a substantial number of students had psychological distress, which could have negative effects on their academic achievement and overall well-being.
INTERNATIONAL JOURNAL OF SOCIAL PSYCHIATRY
(2023)
Article
Public, Environmental & Occupational Health
Abdellah Sabri, Majdouline Obtel, Ahmed Kharbach, Jalal Doufik, Mohamed Amine Baba, Redouane Abouqal, Rachid Razine
Summary: This study aimed to conduct a cross-cultural adaptation of the Explanatory Model Interview Catalogue (EMIC) in the Moroccan Arabic dialect known as Darija, to assess the stigma faced by patients with schizophrenia. The results of the study showed that the adapted Darija version of the measurement tool had high internal consistency and convergent validity, indicating its suitability for studying the phenomenon of stigma in Morocco.
REVUE D EPIDEMIOLOGIE ET DE SANTE PUBLIQUE
(2022)
Editorial Material
Health Policy & Services
Ihsane Hmamouchi, Nelly Ziade
HEALTH POLICY AND TECHNOLOGY
(2022)
Article
Psychiatry
Abdellah Sabri, Majdouline Obtel, Ahmed Kharbach, Jalal Doufik, Mohamed Amine Baba, Abdellah Bouzandag, Redouane Abouqal, Rachid Razine
Summary: This study successfully translated the English version of Stigma Measurement Scale into Berber language and validated its usability in Moroccan society.
IRANIAN JOURNAL OF PSYCHIATRY AND BEHAVIORAL SCIENCES
(2022)
Article
Oncology
Yvon Gauthier, Sebastien Lepreux, Muriel Cario-Andre, Jerome Rambert, Adrien Dakdaki, Marie-Edith Lafon, Redouane Abouqal, Laila Benzekri
Summary: This study reveals the presence of nuclear fusion, cell fusion, and immune reaction related to VZV antigen in segmental vitiligo, suggesting a viral hypothesis for its pathogenesis. The findings provide new insights into the etiology of segmental vitiligo.
PIGMENT CELL & MELANOMA RESEARCH
(2023)
Article
Rheumatology
Pedro David Carvalho, Elsa Vieira-Sousa, Ihsane Hmamouchi, Ana Marreiros, Pedro M. Machado
Summary: This study aimed to assess the hierarchy of outcomes contributing to health-related quality of life in spondyloarthritis and rheumatoid arthritis. The findings revealed that physical function is the main contributor to HRQoL in both diseases, followed by disease activity and work productivity loss.
SEMINARS IN ARTHRITIS AND RHEUMATISM
(2022)
Letter
Rheumatology
Ihsane Hmamouchi, Adewale Adebajo
Article
Rheumatology
Nelly Ziade, Marc Aoude, Ihsane Hmamouchi, R. Naveen, James B. Lilleker, Parikshit Sen, Mrudula Joshi, Vishwesh Agarwal, Sinan Kardes, Jessica Day, Ashima Makol, Marcin Milchert, Tamer Gheita, Babur Salim, Tsvetelina Velikova, Abraham Edgar Gracia-Ramos, Ioannis Parodis, Elena Nikiphorou, Tulika Chatterjee, Ai Lyn Tan, Miguel A. Saavedra, Samuel Katsuyuki Shinjo, Johannes Knitza, Masataka Kuwana, Arvind Nune, Lorenzo Cavagna, Oliver Distler, Hector Chinoy, Vikas Agarwal, Rohit Aggarwal, Latika Gupta
Summary: This study aimed to explore the current practice and interregional differences in the treatment of idiopathic inflammatory myopathies (IIMs). The findings revealed marked regional treatment disparities in a global cohort of IIM and emphasized the need for international consensus-driven management guidelines.
Article
Rheumatology
Ihsane Hmamouchi, Antonella Abi Najm, Lina El Kibbi, Mona Metawee, Hussein Halabi, Nizar Abdulateef, Mervat Eissa, Manal El Rakawi, Basel Masri, Fatma Boutaiban, Wafa Hamdi, Asal Adnan, Renaud Felten, Laurent Arnaud, Nelly Ziade
Summary: The use of online surveys as a recruitment tool for clinical research has expanded recently, but optimal recruitment strategies are yet to be identified. This study aimed to identify the most effective recruitment strategies for online research studies and determine the optimal survey channels for obtaining patients' responses.
RHEUMATOLOGY INTERNATIONAL
(2023)
Review
Endocrinology & Metabolism
Ihsane Hmamouchi, Farhanah Paruk, Samar Tabra, Kaouther Maatallah, Amal Bouziane, Redouane Abouqal, Yasser El Maidany, Abdellah El Maghraoui, Asgar Ali Kalla
Summary: This study found significant variation in the prevalence of glucocorticosteroid-induced osteoporosis (GIOP) in Africa. Limited data is available for most of Africa, and further prospective studies are needed to develop context-specific strategies for GIOP prevention.
ARCHIVES OF OSTEOPOROSIS
(2023)
Article
Rheumatology
Nelly Ziade, Ihsane Hmamouchi, Chafika Haouichat, Fatemah Baron, Sulaiman Al Mayouf, Nizar Abdulateef, Basel Masri, Manal El Mashaleh, Lina El Kibbi, Manal El Mashaleh, Bassel Elzorkany, Jamal Al Saleh, Christian Dejaco, Fatemah Abutiban
Summary: This study investigated the number of rheumatologists in Arab countries and projected future numbers. The findings suggest a 50% increase in rheumatologists, but also highlight the potential increase in demand due to population growth. The study also provides insights into the practice profiles and waiting times for rheumatology consultations.
RHEUMATOLOGY INTERNATIONAL
(2023)
Review
Medicine, General & Internal
Zakariae Cherrat, Rachid Razine, Nada Bennani Mechita, Hayat Sine, Abderrahmane Achbani, Redouane Abouqal, Majdouline Obtel
Summary: This systematic review aims to study the epidemiological, risk factors, and socio-economic characteristics of cancer in Morocco. The review found that cancer mainly affects young, underprivileged, and uninsured populations in Morocco, with a delayed diagnosis. Risk factors identified include smoking, obesity/overweight, and family history.
ANNALS OF CLINICAL AND ANALYTICAL MEDICINE
(2022)
Article
Rheumatology
N. El Ouardi, A. El Maghraoui, H. J. Djossou, L. Taoubane, A. M. Ghassem, H. Toufik, A. Majjad, S. Sadni, A. Mounach, I Hmamouchi, R. Abouqal, R. Bahiri, F. Allali, I El Bouchti, I Ghozlani, H. Hassikou, T. Harzy, L. Ichchou, O. Mkinsi, R. Niamane, A. Bezza
Summary: This study analyzed the reasons for discontinuation of bDMARDs in RA and AS patients in Morocco. The results showed that adverse events were the main cause of discontinuation in RA patients, while social security reimbursement problems were the main cause in AS patients. In addition, female sex and comorbidities increased the risk of discontinuation in RA patients, and the disease activity of AS patients affected the interruption of anti-TNF treatment.
RHEUMATOLOGY INTERNATIONAL
(2022)