Article
Endocrinology & Metabolism
Xiangming Tang, Manabu Niimi, Huanjin Zhou, Lu Chen, Yajie Chen, Haizhao Yan, Masashi Shiomi, Jianglin Fan
Summary: This study examined the pathological features and anatomical distributions of intracranial atherosclerosis (ICAS) using rabbit models. The results showed that ICAS was mainly found in specific locations in the cerebral arteries and was more severe in rabbits with specific genetic mutations. Hypertension was found to promote the development of ICAS in the presence of hypercholesterolemia.
FRONTIERS IN ENDOCRINOLOGY
(2022)
Article
Medicine, General & Internal
Dongyu Fan, Huiyun Li, Dongwan Chen, Yang Chen, Xu Yi, Heng Yang, Qianqian Shi, Fangyang Jiao, Yi Tang, Qiming Li, Fangyang Wang, Shunan Wang, Rongbing Jin, Fan Zeng, Yanjiang Wang
Summary: The study found no significant differences in cortical standard uptake ratios, grey/white ratio, and brain atrophy indices between hypoperfused regions and contralateral normally perfused regions in patients with unilateral chronic cerebral hypoperfusion, suggesting that chronic hypoperfusion may not directly induce cerebral beta-amyloid deposition and neurodegeneration in humans due to large vessel stenosis.
CHINESE MEDICAL JOURNAL
(2022)
Article
Geriatrics & Gerontology
Timothy P. Siejka, Velandai K. Srikanth, Ruth E. Hubbard, Chris Moran, Richard Beare, Amanda G. Wood, Taya A. Collyer, Siddhanth Gujjari, Thanh G. Phan, Michele L. Callisaya
Summary: This study examined the effect of frailty on cognitive decline and found that frailty is associated with early cognitive dysfunction. Measuring frailty may help identify the risk of cognitive decline.
JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
(2022)
Article
Radiology, Nuclear Medicine & Medical Imaging
Meher R. Juttukonda, Larry T. Davis, Sarah K. Lants, Spencer L. Waddle, Chelsea A. Lee, Niral J. Patel, Lori C. Jordan, Manus J. Donahue
Summary: The study found that an elevated CVRDELAY in patients with atherosclerosis may indicate brain parenchyma at increased risk for new infarcts. 15% of participants were found to have new infarcts during follow-up.
JOURNAL OF MAGNETIC RESONANCE IMAGING
(2021)
Article
Cardiac & Cardiovascular Systems
Ville Rantasalo, Jarmo Gunn, Tuomas Kiviniemi, Jussi Hirvonen, Ilkka Saarenpaa, Juri Kivelev, Melissa Rahi, Elli Lassila, Jaakko Rinne, Dan Laukka
Summary: The study revealed that abdominal aortic calcification is more prominent in patients with ruptured and unruptured intracranial aneurysms compared to matched controls, and increases the risk for ruptured aneurysms.
Article
Radiology, Nuclear Medicine & Medical Imaging
Kangmo Huang, Weihe Yao, Mingming Zha, Shanmei Qin, Yingle Li, Yan Xu, Rui Liu, Ruidong Ye, Yunfei Han, Wusheng Zhu, Zhongzhao Teng, Juan Du, Xinfeng Liu
Summary: This study aimed to evaluate the predictive value of hemodynamic features for stroke relapse in patients with intracranial vertebrobasilar atherosclerotic stenosis treated with PTAS using q-DSA. The results showed that preprocedural prolonged time to peak in the target vessel and shortened trans-stenotic time to peak difference were associated with stroke relapse. Hemodynamic parameters defined by q-DSA provided incremental predictive value for stroke recurrence.
EUROPEAN RADIOLOGY
(2023)
Article
Oncology
Chika Shichijo, Keita Kai, Kazuki Jinnouchi, Masashi Nishihara, Hideo Hara, Shinichi Aishima
Summary: In this study, the pathology of cerebral infarction (CI) was compared between cases with and without malignancy, focusing on intracranial Monckeberg's atherosclerosis. The results indicated that Monckeberg's atherosclerosis was frequently found in the basal ganglia of CI patients with malignancy, suggesting it as a potential risk factor for CI in patients with advanced stage malignancy.
Article
Cardiac & Cardiovascular Systems
Juho Mattila, Niina Pitkanen, Hannu Jarvelainen
Summary: This study demonstrates for the first time that CVID is an independent risk factor for atherosclerotic cardiovascular diseases, with increased risk of coronary heart disease and peripheral vascular disease.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2023)
Article
Clinical Neurology
Andrew Micieli, Andrew M. Demchuk, Harindra C. Wijeysundera
Summary: In patients with factor Xa-associated intracranial hemorrhage, Andexanet has shown to have a higher cost-effectiveness ratio compared to PCC. The use of Andexanet can reduce fatal ICrH and increase thromboembolic events.
Article
Cardiac & Cardiovascular Systems
Jose Gutierrez, Farid Khasiyev, Minghua Liu, Janet T. DeRosa, Sarah E. Tom, Tatjana Rundek, Ken Cheung, Clinton B. Wright, Ralph L. Sacco, Mitchell S. V. Elkind
Summary: The study identified the role of risk factors and risk of vascular events in subjects with asymptomatic ICAS for improved risk stratification. Older age, duration of hypertension, number of glucose-lowering drugs, and high-density lipoprotein were associated with ICAS. The highest event risk was noted among participants with ICAS >= 70%.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
(2021)
Article
Medicine, General & Internal
Yanhua Huang, Zuoteng Wang, Bing Zhao, Yahui Ma, Yanan Ou, Hao Hu, Xiaohe Hou, Jintai Yu, Lan Tan
Summary: This study investigated the association between the platelet-to-lymphocyte ratio (PLR) and intracranial atherosclerotic stenosis (ICAS) in a Chinese Han population. The results showed that a high PLR was significantly associated with an increased risk of ICAS, particularly in the elderly population.
CHINESE MEDICAL JOURNAL
(2022)
Article
Biochemistry & Molecular Biology
Zsolt Bagyura, Loretta Kiss, Arpad Lux, Csaba Csobay-Novak, Adam L. Jermendy, Livia Polgar, Adam G. Tabak, Pal Soos, Zsolt Szelid, Bela Merkely, Laszlo Kohidai, Eva Pallinger
Summary: Several inflammatory biomarkers are associated with an increased risk of cardiovascular disease. Neutrophil-to-lymphocyte ratio (NLR) and visceral adiposity index (VAI) are markers of subclinical inflammation and reflect the function and extent of adipose tissue. This study aimed to examine the association between NLR and coronary artery calcium score (CACS) in asymptomatic patients across different VAI tertiles.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Jin Li, Hengqu Wu, Hailun Hang, Beibei Sun, Huilin Zhao, Zengai Chen, Yan Zhou, Jianrong Xu, Jinmei Chen, Dan Zhou, Xihai Zhao, Chun Yuan
Summary: This study investigated the association between carotid vulnerable plaque features coexisting with cerebral small vessel diseases (CSVDs) and acute ischemic stroke (AIS), and determined whether coexisting diseases had a stronger association with AIS than a single disease. The results showed that carotid vulnerable plaque features coexisting with lacunes or moderate-to-severe white matter hyperintensities had a stronger association with AIS compared to carotid lesions alone.
EUROPEAN RADIOLOGY
(2022)
Article
Cardiac & Cardiovascular Systems
Yinjie Guo, Canxia Xu, Linfang Zhang, Zhiheng Chen, Xiujuan Xia
Summary: This study found that Helicobacter pylori infection may be an important independent risk factor for stroke in women. The infection was significantly associated with higher incidence of intracranial atherosclerosis, particularly in women <= 60 years of age. In vitro experiments further demonstrated that H. pylori infection affects migration, tube formation, and proliferation of brain endothelial cells.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2022)
Article
Nutrition & Dietetics
Linda K. McEvoy, Jaclyn Bergstrom, Xinming Tu, Alexis C. Garduno, Kevin M. Cummins, Carol E. Franz, Michael J. Lyons, Chandra A. Reynolds, William S. Kremen, Matthew S. Panizzon, Gail A. Laughlin
Summary: The study found that middle-aged men who consume alcohol in moderation have lower cardiovascular disease (CVD) risk and better cardiometabolic health than men who consume little or no alcohol, independent of a variety of health, behavioral, psychosocial, and earlier life factors.
Letter
Cardiac & Cardiovascular Systems
Muhammad Aftab, T. Brett Reece, Lars G. Svensson
ANNALS OF THORACIC SURGERY
(2020)
Editorial Material
Cardiac & Cardiovascular Systems
Muhammad Aftab, T. Brett Reece
JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY
(2020)
Editorial Material
Cardiac & Cardiovascular Systems
Andrew Mesher, Muhammad Aftab, Thomas G. Gleason, T. Brett Reece
JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY
(2020)
Article
Surgery
Benjamin R. Griffin, Patrick D. Kohtz, Michael Bronsert, T. Brett Reece, Joseph C. Cleveland, David A. Fullerton, Sarah Faubel, Muhammad Aftab
JOURNAL OF SURGICAL RESEARCH
(2020)
Article
Cardiac & Cardiovascular Systems
Benjamin R. Griffin, J. Pedro Teixeira, Sophia Ambruso, Michael Bronsert, Jay D. Pal, Joseph C. Cleveland, T. Brett Reece, David A. Fullerton, Sarah Faubel, Muhammad Aftab
Summary: This study aimed to investigate the association between stage 1 AKI after surgery and postoperative infection and mortality. The results showed that stage 1 AKI was independently associated with increased infection, ICU LOS, and hospital LOS. Treatment strategies focusing on AKI prevention, early recognition, and optimal medical management may reduce significant postoperative morbidity.
JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY
(2021)
Letter
Cardiac & Cardiovascular Systems
Benjamin R. Griffin, T. Brett Reece, Muhammad Aftab
ANNALS OF THORACIC SURGERY
(2020)
Editorial Material
Cardiac & Cardiovascular Systems
Christian V. Ghincea, Yuki Ikeno, Michael J. Weyant, John D. Mitchell, Muhammad Aftab, T. Brett Reece
ANNALS OF THORACIC SURGERY
(2020)
Editorial Material
Cardiac & Cardiovascular Systems
Andrew L. Mesher, Muhammad Aftab, T. Brett Reece
JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY
(2021)
Article
Cardiac & Cardiovascular Systems
Ryan G. Aleong, Matthew M. Zipse, Christine Tompkins, Muhammad Aftab, Paul Varosy, William Sauer, David Kao
JOURNAL OF THE AMERICAN HEART ASSOCIATION
(2020)
Article
Cardiac & Cardiovascular Systems
Navin G. Vigneshwar, Patrick D. Kohtz, Mark T. Lucas, Michael Bronsert, Michael J. Weyant, Muhammad F. Masood, Akinobu Itoh, Jessica Y. Rove, Thomas B. Reece, Joseph C. Cleveland, Jay D. Pal, David A. Fullerton, Muhammad Aftab
JOURNAL OF CARDIAC SURGERY
(2020)
Editorial Material
Cardiac & Cardiovascular Systems
Yihan Lin, Muhammad Aftab, T. Brett Reece
SEMINARS IN THORACIC AND CARDIOVASCULAR SURGERY
(2020)
Review
Anesthesiology
Jordan R. H. Hoffman, Kelly C. Higa, Yihan Lin, T. Brett Reece, Joseph C. Cleveland, Muhammad Aftab, Jessica Y. Rove
Summary: Cardiac surgery is continuously progressing and has been influenced by guidelines for coronary revascularization and the ongoing pandemic. Advances in organ procurement and dissection care have benefitted from improved understanding and technology.
SEMINARS IN CARDIOTHORACIC AND VASCULAR ANESTHESIA
(2022)
Meeting Abstract
Cardiac & Cardiovascular Systems
Yuki Ikeno, Christian V. Ghincea, Gavriel Roda, Linling Cheng, Muhammad Aftab, Xianzhong Meng, Michael Weyant, Joseph Cleveland, David A. Fullerton, Thomas B. Reece
Article
Anesthesiology
Christian V. Ghincea, T. Brett Reece, Muhammad Aftab, Joseph C. Cleveland, Jay D. Pal
SEMINARS IN CARDIOTHORACIC AND VASCULAR ANESTHESIA
(2020)
Meeting Abstract
Cardiac & Cardiovascular Systems
Andrew Nickel, Jamaluddin Moloo, Muhammad Aftab, Ryan Aleong, Matthew Zipse
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
(2020)