☆ 4.5 Article

Cognitive impairment in patients with Fibromyalgia syndrome as assessed by the Mini-Mental State Examination

BMC MUSCULOSKELETAL DISORDERS (2009)

Journal

BMC MUSCULOSKELETAL DISORDERS

Volume 10, Issue -, Pages -

Publisher

BMC

DOI: 10.1186/1471-2474-10-162

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Categories

Orthopedics Rheumatology

Funding

Pfizer Espana

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Reagent

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Abstract

Background: This study evaluated the frequency of cognitive impairment in patients with Fibromyalgia syndrome (FMS) using the Mini Mental State Examination (MMSE). Methods: We analyzed baseline data from all 46 patients with FMS and 92 age- and sex-matched controls per diagnosis of neuropathic (NeP) or mixed pain (MP) selected from a larger prospective study. Results: FMS had a slight but statistically significant lower score in the adjusted MMSE score (26.9; 95% CI 26.7-27.1) than either NeP (27.3; 95% CI 27.2-27.4) or MP (27.3; 27.2-27.5). The percentage of patients with congnitive impairment (adjusted MMSE <= 26) was numerically higher in FMS (15%; 95% CI 6.3-29) compared with NeP (5%; 95% CI 1.8-12.2) or MP (5%; 95% CI 1.8-12.2) and higher than in the same age stratum of the general population (0.05%). Conclusions: Compared with the population reference value, patients with FMS showed high frequency of cognitive impairment.

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