Striking reduction of amyloid plaque burden in an Alzheimer's mouse model after chronic administration of carmustine

Effect of Immunotherapy With Bapineuzumab on Cerebrospinal Fluid Biomarker Levels in Patients With Mild to Moderate Alzheimer Disease

(2012) Henrik Zetterberg   ARCHIVES OF NEUROLOGY

A mutation in APP protects against Alzheimer’s disease and age-related cognitive decline

(2012) Thorlakur Jonsson et al.   NATURE

Accelerated cortical atrophy in cognitively normal elderly with high  -amyloid deposition

(2012) G. Chetelat et al.   NEUROLOGY

ApoE-Directed Therapeutics Rapidly Clear  -Amyloid and Reverse Deficits in AD Mouse Models

(2012) P. E. Cramer et al.   SCIENCE

2011 Alzheimer’s disease facts and figures

(2011)   Alzheimers & Dementia

The CC genotype of transforming growth factor-β1 increases the risk of late-onset Alzheimer's disease and is associated with AD-related depression

(2011) Filippo Caraci et al.   EUROPEAN NEUROPSYCHOPHARMACOLOGY

Growth arrest-specific 1 binds to and controls the maturation and processing of the amyloid-β precursor protein

(2011) Julien Chapuis et al.   HUMAN MOLECULAR GENETICS

Robust Central Reduction of Amyloid-  in Humans with an Orally Available, Non-Peptidic  -Secretase Inhibitor

(2011) P. C. May et al.   JOURNAL OF NEUROSCIENCE

The worldwide societal costs of dementia: Estimates for 2009

(2010) Anders Wimo et al.   Alzheimers & Dementia

Amyloid-β associated cortical thinning in clinically normal elderly

(2010) J. Alex Becker et al.   ANNALS OF NEUROLOGY

What Can Be Inferred from the Interruption of the Semagacestat Trial for Treatment of Alzheimer's Disease?

(2010) Jeffrey Cummings   BIOLOGICAL PSYCHIATRY

Gamma-secretase activating protein is a therapeutic target for Alzheimer’s disease

(2010) Gen He et al.   NATURE

Alzheimer's failure raises questions about disease-modifying strategies

(2010) Andy Extance   NATURE REVIEWS DRUG DISCOVERY

 -Secretase-dependent amyloid-  is increased in Niemann-Pick type C: A cross-sectional study

(2010) N. Mattsson et al.   NEUROLOGY

Metallothionein Induction Reduces Caspase-3 Activity and Tnfα Levels with Preservation of Cognitive Function and Intact Hippocampal Neurons in Carmustine-Treated Rats

(2010) Gouda K. Helal et al.   Oxidative Medicine and Cellular Longevity

Homotaurine: A failed drug for Alzheimer’s disease and now a nutraceutical for memory protection

(2009) Michael T. Swanoski   AMERICAN JOURNAL OF HEALTH-SYSTEM PHARMACY

Long-Term Follow-Up of Patients Immunized with AN1792: Reduced Functional Decline in Antibody Responders

(2009) Bruno Vellas et al.   Current Alzheimer Research

Inhibition of acyl-coenzyme A: cholesterol acyl transferase modulates amyloid precursor protein trafficking in the early secretory pathway

(2009) Henri J. Huttunen et al.   FASEB JOURNAL

A fragment of the scaffolding protein RanBP9 is increased in Alzheimer’s disease brains and strongly potentiates amyloid-β peptide generation

(2009) Madepalli K. Lakshmana et al.   FASEB JOURNAL

Effect of Tarenflurbil on Cognitive Decline and Activities of Daily Living in Patients With Mild Alzheimer DiseaseA Randomized Controlled Trial

(2009) Robert C. Green   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Novel Role of RanBP9 in BACE1 Processing of Amyloid Precursor Protein and Amyloid β Peptide Generation

(2009) Madepalli K. Lakshmana et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Zinc Inhibits Amyloid β Production from Alzheimer's Amyloid Precursor Protein in SH-SY5Y Cells

(2009) Jinu Lee et al.   KOREAN JOURNAL OF PHYSIOLOGY & PHARMACOLOGY

Cancer linked to Alzheimer disease but not vascular dementia

(2009) C. M. Roe et al.   NEUROLOGY

β-Amyloid, Blood Vessels, and Brain Function

(2009) Eric E. Smith et al.   STROKE

Clinical activity of laromustine (Onrigin™) in hematologic malignancies

(2009) Yesid Alvarado et al.   Expert Review of Hematology