Article
Biology
Jose A. Parraca, Jose Carmelo Adsuar, Francisco Javier Dominguez-Munoz, Sabina Barrios-Fernandez, Pablo Tomas-Carus
Summary: Strength is essential for maintaining the quality of life in elderly individuals. This study aimed to assess the intra-session reliability of isokinetic dynamometry for measuring lower limb strength in older people. The results showed excellent reliability for peak torque and work in all measures, except for left leg flexors in women, which had good reliability. These findings demonstrate the utility of isokinetic dynamometry for monitoring lower limb maximal muscle strength and work in the elderly.
Article
Neurosciences
Veerle de Rond, Moran Gilat, Nicholas D'Cruz, Femke Hulzinga, Jean-Jacques Orban de Xivry, Alice Nieuwboer
Summary: The test-retest reliability of fNIRS measurements during postural and finger-tapping tasks was investigated in this study. The results showed that the reliability was excellent when the cap was kept on during the measurements, but it reduced when the cap was removed.
Article
Neurosciences
Gang Chen, Daniel S. Pine, Melissa A. Brotman, Ashley R. Smith, Robert W. Cox, Simone P. Haller
Summary: This article discusses the issue of reliability in neuroimaging studies using the test-retest method, highlighting the risk of low reliability in common cognitive tasks. It proposes a hierarchical framework to evaluate reliability, suggesting that traditional intraclass correlation statistics may underestimate reliability and more trials are needed for accurate reliability estimates.
Article
Neurosciences
Hengyi Cao, Anita D. Barber, Jose M. Rubio, Miklos Argyelan, Juan A. Gallego, Todd Lencz, Anil K. Malhotra
Summary: This study investigates the influence of phase encoding direction (PED) on the test-retest reliability of functional connectome in fMRI studies. The results show that PA scans have significantly higher intraclass correlation coefficients (ICCs) for global, nodal, and edge connectivity compared to AP scans. Better temporal signal-to-noise ratio (tSNR) reliability is also observed in PA scans. Averaging the connectivity outcome from both PEDs can increase ICCs, especially at the nodal and edge levels.
Article
Multidisciplinary Sciences
Jiang Zhang, Xinzhi Teng, Xinyu Zhang, Sai-Kit Lam, Zhongshi Lin, Yongyi Liang, Hao Yu, Steven Wai Kwan Siu, Amy Tien Yee Chang, Hua Zhang, Feng-Ming Kong, Ruijie Yang, Jing Cai
Summary: This study compared the impact of repeatable features determined by two methods on the reliability of radiomic models. The findings suggest that image perturbation can achieve similar reliability to test-retest imaging under specific conditions. However, careful consideration is needed when determining the optimal feature repeatability criteria.
SCIENTIFIC REPORTS
(2023)
Article
Psychology, Mathematical
Jessica V. Schaaf, Laura Weidinger, Lucas Molleman, Wouter van den Bos
Summary: It has been suggested that parameter estimates of computational models can help understand individual differences at the process level. Computational psychiatry is a research field that has embraced this approach, known as computational phenotyping. This study investigates the test-retest reliability of reinforcement learning models in two common learning paradigms and finds that while reliability is high for personality and cognitive measures, it is generally poor for the parameter estimates of the models.
BEHAVIOR RESEARCH METHODS
(2023)
Article
Psychology, Mathematical
Hilmar G. Zech, Philip Gable, Wilco W. van Dijk, Lotte F. van Dillen
Summary: The approach-avoidance task (AAT) is an implicit task used to measure people's behavioral tendencies to approach or avoid stimuli in the environment. While it has been successfully used to explain various health problems, recent studies have failed to replicate earlier findings, indicating unreliable measurement of approach-avoidance tendencies. This study examines the reliability of the AAT in a large and diverse sample using a mobile AAT, suggesting the need for multiple measurements in future research.
BEHAVIOR RESEARCH METHODS
(2023)
Article
Neurosciences
Lei Wang, Xiaodan Chen, Yuehua Xu, Miao Cao, Xuhong Liao, Yong He
Summary: The study discovered that functional hubs in the human brain network can be classified into three types (low-frequency, middle-frequency, and high-frequency) based on different frequency bands, with the hubs mainly distributed in regions such as the frontal lobe, parietal lobe, prefrontal cortex, temporal lobe, amygdala, and cerebellum.
NEUROSCIENCE BULLETIN
(2022)
Article
Clinical Neurology
David Morley, Sarah Dummett, Laura Kelly, Crispin Jenkinson
Summary: This study assessed the test-retest reliability of PDQ-Carer. The results indicate that PDQ-Carer demonstrates sound test-retest reliability and can be confidently used in studies of carers of PwP.
PARKINSONISM & RELATED DISORDERS
(2022)
Article
Multidisciplinary Sciences
Yanzhi Bi, Xin Hou, Jiahui Zhong, Li Hu
Summary: This experiment found significant changes in laser-evoked pain perception and brain responses across different sessions, with fair to moderate test-retest reliability. Lower resting-state brain activity and functional connectivity were observed in the second session. This suggests that changes in baseline mental state may influence laser-evoked pain perception and brain responses.
SCIENTIFIC REPORTS
(2021)
Article
Neurosciences
Yun Wang, Walter Hinds, Cristiane S. Duarte, Seonjoo Lee, Catherine Monk, Melanie Wall, Glorisa Canino, Ana Carolina C. Milani, Andrea Jackowski, Marina Griorgi Mamin, Bernd U. Foerster, Jay Gingrich, Myrna M. Weissman, Bradley S. Peterson, David Semanek, Edna Acosta Perez, Eduardo Labat, Ioannisely Berrios Torres, Ivaldo Da Silva, Camila Parente, Nitamar Abdala, Jonathan Posner
Summary: Resting functional MRI studies of the infant brain have shown poor edge-level reliability but moderate-to-good subject-level intra-session reliability for whole-brain, default mode network, and sensorimotor network connectivity. Factors such as run duration, study site, and scanning manufacturer significantly affect reliability estimates, while some ICA-derived networks exhibit strong spatial reproducibility. The study suggests that examining the functional organization of major neural networks in infants is generally reliable, but interpretation of functional connectivity should be done carefully for ongoing success.
Article
Orthopedics
Sara Kardor, Zahra Gorji, Nastaran Ghotbi, Behrouz Attarbashi-Moghadam, Azadeh Shadmehr, Mona Gorji
Summary: This study aimed to assess the relative and absolute test-retest reliability of upper limb power and stability tests in female overhead athletes. The results showed that these tests have acceptable reliability in this population.
JOURNAL OF ORTHOPAEDIC SURGERY AND RESEARCH
(2023)
Article
Physiology
Yue Li, Ning Yu, Cui Zhang, Qipeng Song, Jiangna Wang, Wei Sun
Summary: This study evaluated the test-retest reliability of kinematics and kinetics during single and dual-task stair walking in the elderly. The results showed good test-retest reliability of kinematic and kinetic parameters during stair walking in both single and dual task conditions, except for step length in ascending stairs. These findings can assist researchers in assessing the biomechanics of dual-task stair walking in the elderly and interpreting the effects of interventions in this population.
FRONTIERS IN PHYSIOLOGY
(2023)
Article
Chemistry, Analytical
Andreas Loukovitis, Efthymios Ziagkas, Dimitrios Xypolias Zekakos, Alexandros Petrelis, George Grouios
Summary: Gait analysis is an important tool for quantifying human locomotion, and PODOSmart(R) insoles are designed to provide accurate measurements for this purpose. A recent study confirmed the excellent repeatability of PODOSmart(R) in capturing various gait parameters, making it a reliable tool for research and clinical settings.
Article
Substance Abuse
Justin C. Strickland, Olga A. Vsevolozhskaya, William W. Stoops
Summary: This study compares different methods of operationalizing e-cigarette purchases and finds that the puff version has the largest effect size correlations. The results suggest that puffs as an experimental commodity may offer flexibility in studying e-cigarette demand and could be effective in researching demand among different populations.
NICOTINE & TOBACCO RESEARCH
(2021)
Article
Geriatrics & Gerontology
Serena Sabatini, Anthony Martyr, Laura D. Gamble, Ian R. Jones, Rachel Collins, Fiona E. Matthews, Christina R. Victor, Catherine Quinn, Claire Pentecost, Jeanette M. Thom, Linda Clare
Summary: This study explored the social, cultural, and economic capital of spousal carers of people with dementia, and the profiles of carers with different levels of capital. The results showed that carers with lower capital experienced less stress and reported more positive experiences in caring over time. However, compared to carers with better capital, those with poorer capital were more likely to be depressed over time.
AGING & MENTAL HEALTH
(2023)
Article
Clinical Neurology
Andrea Burgess, Leanne Sakzewski, Koa Whittingham, Jane Wotherspoon, Mark D. Chatfield, Robert S. Ware, Roslyn N. Boyd
Summary: This study aimed to describe the development of social function in children with cerebral palsy (CP) and its correlation with the level of communication function. The findings suggest that social function is closely related to the level of communication function in children with CP, highlighting the importance of considering individual differences based on communication function levels in assessing social function in these children.
DEVELOPMENTAL MEDICINE AND CHILD NEUROLOGY
(2023)
Article
Rehabilitation
Anna L. Hatton, Katrina Williams, Mark D. Chatfield, Sheree E. Hurn, Jayishni N. Maharaj, Elise M. Gane, Thomas Cattagni, John Dixon, Keith Rome, Graham Kerr, Sandra G. Brauer
Summary: This study investigated the immediate effects of wearing novel sensory-stimulating textured insoles on balance and gait in people with multiple sclerosis (pwMS). The results showed that wearing textured insoles reduced center of pressure (CoP) movement during standing and did not consistently improve gait compared to smooth insoles or shoes only. Walking barefoot led to poorer gait performance. The study suggests that stimulating the foot with texture could be a potential new treatment option for balance rehabilitation in pwMS, but further research is needed to determine who would benefit the most from textured insoles.
DISABILITY AND REHABILITATION
(2023)
Article
Geriatrics & Gerontology
Connor D. Richardson, Hannah Roscoe, Emma Green, Racheal Brooks, Linda Barnes, Fiona E. Matthews, Carol Brayne
Summary: The prevalence of loneliness among older people has increased during the COVID-19 pandemic compared to before. Factors associated with prevalent loneliness include prior loneliness, living alone, being female, living in a deprived area, separation from family during the pandemic, and frequent pre-pandemic social contact at community groups. Weekly technology-mediated contact using telephone or video calls is associated with lower odds of loneliness.
JOURNAL OF THE AMERICAN GERIATRICS SOCIETY
(2023)
Article
Multidisciplinary Sciences
Deborah L. O. King, Richard Henson, Rogier Kievit, Noham Wolpe, Carol Brayne, Lorraine K. Tyler, James B. A. Rowe, Kamen A. Tsvetanov, Cam-CAN
Summary: Cardiovascular ageing is associated with cognitive impairment, but the specific contributions of different cardiovascular factors to cognitive function are not clear.
SCIENTIFIC REPORTS
(2023)
Article
Public, Environmental & Occupational Health
Serena Sabatini, Anthony Martyr, Laura D. Gamble, Ian R. Jones, Rachel Collins, Fiona E. Matthews, Martin Knapp, Jeanette M. Thom, Catherine Henderson, Christina Victor, Claire Pentecost, Linda Clare, IDEAL Programme Team
Summary: This study describes the levels of social, cultural, and economic capital among people with dementia and examines the differences in personal characteristics and quality of life over time based on different combinations of capital. The results show that people with dementia have relatively lower levels of social, cultural, and economic capital, although they are not significantly lower compared to older adults in the UK. The study identifies four groups of people with dementia based on their capital levels and finds that higher levels of capital are associated with higher quality of life and well-being. Therefore, efforts from the government and society are needed to address the social, cultural, and economic disadvantages among people with dementia.
SOCIAL SCIENCE & MEDICINE
(2023)
Article
Geriatrics & Gerontology
Asri Maharani, David R. Sinclair, Tarani Chandola, Peter Bower, Andrew Clegg, Barbara Hanratty, James Nazroo, Neil Pendleton, Gindo Tampubolon, Chris Todd, Raphael Wittenberg, Terence W. O'Neill, Fiona E. Matthews
Summary: This study investigated the relationship between household wealth and neighborhood deprivation with frailty status, and found that individuals with lower wealth and living in deprived neighborhoods are at a higher risk of frailty.
Article
Clinical Neurology
Mohammed D. Rajab, Emmanuel Jammeh, Teruka Taketa, Carol Brayne, Fiona E. Matthews, Li Su, Paul G. Ince, Stephen B. Wharton, Dennis Wang
Summary: This study applies machine learning approaches to identify critical features of Alzheimer-related pathologies associated with dementia. Results show that Braak neurofibrillary tangle stage, beta-amyloid, and cerebral amyloid angiopathy are the most important features for dementia classification. The best-performing dementia classifier achieved 79% sensitivity, 69% specificity, and 75% precision using the top eight neuropathological features.
ALZHEIMERS RESEARCH & THERAPY
(2023)
Article
Communication
Ahmet Begde, Manisha Jain, Maria Goodwin, Carol Brayne, Linda Barnes, Rachael Brooks, Emma Green, Connor Richardson, Tom Dening, Thomas Wilcockson, Eef Hogervorst
Summary: Technology is seen as a solution for the aging population in the UK to improve independence and health. However, factors such as age, gender, access to technology, and physical health affect older adults' willingness to use memory assistive and ADL supportive technologies. Healthcare providers, policymakers, and technology producers should target older people, females, and those with less access to technology to promote healthy and independent aging.
INFORMATION COMMUNICATION & SOCIETY
(2023)
Article
Clinical Neurology
Anthony Martyr, Madhumathi Ravi, Laura D. Gamble, Robin G. Morris, Jennifer M. Rusted, Claire Pentecost, Fiona E. Matthews, Linda Clare, DEAL study team
Summary: This study compared the trajectories of cognition and instrumental activities of daily living (iADL) in people with dementia. The results showed that cognition and self-rated iADL declined at a similar rate, while informant-rated iADL declined at a significantly higher rate than cognition. This suggests that either cognition and self-rated iADL decline at different rates or informants overestimate iADL difficulties compared to both cognition and self-ratings.
ALZHEIMERS & DEMENTIA
(2023)
Letter
Clinical Neurology
Sebastian Walsh, Richard Merrick, Carol Brayne
Article
Geriatrics & Gerontology
Emma Nichols, Richard Merrick, Simon Hay, Dibya Himali, Jayandra J. Himali, Sally Hunter, Hannah A. D. Keage, Caitlin S. Latimer, Matthew R. Scott, Jaimie Steinmetz, Jamie M. Walker, Stephen B. Wharton, Crystal Wiedner, Paul K. Crane, Dirk Keene, Lenore J. Launer, Fiona E. Matthews, Julie Schneider, Sudha Seshadri, Lon White, Carol Brayne, Theo Vos
Summary: This study aimed to harmonise neuropathology measures across multiple community-based autopsy cohorts and assess the prevalence, correlation, and co-occurrence of neuropathologies in the ageing population. The results showed that the co-occurrence of neuropathologies in older adults was strongly associated with dementia status, highlighting the complexity of underlying brain pathologies. Rating: 9 out of 10.
LANCET HEALTHY LONGEVITY
(2023)
Letter
Clinical Neurology
Sebastian Walsh, Richard Merrick, Carol Brayne