DNA microarray profiling of genes differentially regulated by the histone deacetylase inhibitors vorinostat and LBH589 in colon cancer cell lines

Gene microarray analysis of human renal cell carcinoma: The effects of HDAC inhibition and retinoid treatment

(2010) Trisha S. Tavares et al.   CANCER BIOLOGY & THERAPY

Aurora A, Aurora B and survivin are novel targets of transcriptional regulation by histone deacetylase inhibitors in non-small cell lung cancer

(2010) Xu-Hui Zhang et al.   CANCER BIOLOGY & THERAPY

The role of histone deacetylases in prostate cancer

(2010) Ata Abbas et al.   Epigenetics

Connective tissue growth factor: Context-dependent functions and mechanisms of regulation

(2009) Iwona Cicha et al.   BIOFACTORS

Development of vorinostat: Current applications and future perspectives for cancer therapy

(2009) Victoria M. Richon et al.   CANCER LETTERS

Development of the pan-DAC inhibitor panobinostat (LBH589): Successes and challenges

(2009) Peter Atadja   CANCER LETTERS

A Phase I, Pharmacokinetic and Pharmacodynamic Study on Vorinostat in Combination with 5-Fluorouracil, Leucovorin, and Oxaliplatin in Patients with Refractory Colorectal Cancer

(2009) M. G. Fakih et al.   CLINICAL CANCER RESEARCH

Dual Degradation of Aurora A and B Kinases by the Histone Deacetylase Inhibitor LBH589 Induces G2-M Arrest and Apoptosis of Renal Cancer Cells

(2009) T.-L. Cha et al.   CLINICAL CANCER RESEARCH

Protein Acetylation and Histone Deacetylase Expression Associated with Malignant Breast Cancer Progression

(2009) J. Suzuki et al.   CLINICAL CANCER RESEARCH

Downregulation of connective tissue growth factor by three-dimensional matrix enhances ovarian carcinoma cell invasion

(2009) Maria V. Barbolina et al.   INTERNATIONAL JOURNAL OF CANCER

Histone deacetylase inhibitors suppress thymidylate synthase gene expression and synergize with the fluoropyrimidines in colon cancer cells

(2009) William Fazzone et al.   INTERNATIONAL JOURNAL OF CANCER

The histone deacetylase inhibitor LBH589 inhibits expression of mitotic genes causing G2/M arrest and cell death in head and neck squamous cell carcinoma cell lines

(2009) Michael B Prystowsky et al.   JOURNAL OF PATHOLOGY

Histone Deacetylase Inhibitor Romidepsin Enhances Anti-Tumor Effect of Erlotinib in Non-small Cell Lung Cancer (NSCLC) Cell Lines

(2009) Wei Zhang et al.   Journal of Thoracic Oncology

The proteasome inhibitor bortezomib interacts synergistically with the histone deacetylase inhibitor suberoylanilide hydroxamic acid to induce T-leukemia/lymphoma cells apoptosis

(2009) Q-L Zhang et al.   LEUKEMIA

Vorinostat and bortezomib exert synergistic antiproliferative and proapoptotic effects in colon cancer cell models

(2009) T. M. Pitts et al.   MOLECULAR CANCER THERAPEUTICS

Phosphatidylinositol 3-kinase signaling in proliferating cells maintains an anti-apoptotic transcriptional program mediated by inhibition of FOXO and non-canonical activation of NFκB transcription factors

(2008) Jolyon Terragni et al.   BMC CELL BIOLOGY

Histone deacetylase inhibitors: Mechanisms of cell death and promise in combination cancer therapy

(2008) Jennifer S. Carew et al.   CANCER LETTERS

Inhibition of Fibroblast Growth Factor 19 Reduces Tumor Growth by Modulating  -Catenin Signaling

(2008) R. Pai et al.   CANCER RESEARCH

An Inactivating Mutation in HDAC2 Leads to Dysregulation of Apoptosis Mediated by APAF1

(2008) Christin L. Hanigan et al.   GASTROENTEROLOGY

Prognostic significance of the therapeutic targets histone deacetylase 1, 2, 6 and acetylated histone H4 in cutaneous T-cell lymphoma

(2008) L Marquard et al.   HISTOPATHOLOGY

CCAAT box is required for the induction of human thrombospondin‐1 gene by trichostatin A

(2008) Jung‐Hoon Kang et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Metallothionein 1G acts as an oncosupressor in papillary thyroid carcinoma

(2008) Cristina Ferrario et al.   LABORATORY INVESTIGATION

HDAC4 Promotes Growth of Colon Cancer Cells via Repression of p21

(2008) Andrew J. Wilson et al.   MOLECULAR BIOLOGY OF THE CELL

Novel opportunities for thymidylate metabolism as a therapeutic target

(2008) P. M. Wilson et al.   MOLECULAR CANCER THERAPEUTICS

Regulation of human dUTPase gene expression and p53-mediated transcriptional repression in response to oxaliplatin-induced DNA damage

(2008) Peter M. Wilson et al.   NUCLEIC ACIDS RESEARCH

Combination therapy of established cancer using a histone deacetylase inhibitor and a TRAIL receptor agonist

(2008) A. J. Frew et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Histone deacetylase 3 localizes to the mitotic spindle and is required for kinetochore-microtubule attachment

(2008) S. Ishii et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA