Nucleotide-binding oligomerization domain containing-like receptor family, caspase recruitment domain (CARD) containing 4 (NLRC4) regulates intrapulmonary replication of aerosolized Legionella pneumophila

NAIP and Ipaf Control Legionella pneumophila Replication in Human Cells

(2014) M. Vinzing et al.   JOURNAL OF IMMUNOLOGY

Cutting Edge: Inflammasome Activation by Alum and Alum's Adjuvant Effect Are Mediated by NLRP3

(2014) H. Li et al.   JOURNAL OF IMMUNOLOGY

An NLRP7-Containing Inflammasome Mediates Recognition of Microbial Lipopeptides in Human Macrophages

(2012) Sonal Khare et al.   IMMUNITY

Global cellular changes induced by Legionella pneumophila infection of bone marrow-derived macrophages

(2011) Anne Fortier et al.   IMMUNOBIOLOGY

Activation of NLRC4 by Flagellated Bacteria Triggers Caspase-1-Dependent and -Independent Responses To Restrict Legionella pneumophila Replication in Macrophages and In Vivo

(2011) M. S. F. Pereira et al.   JOURNAL OF IMMUNOLOGY

The NLRC4 inflammasome receptors for bacterial flagellin and type III secretion apparatus

(2011) Yue Zhao et al.   NATURE

Innate immune recognition of bacterial ligands by NAIPs determines inflammasome specificity

(2011) Eric M. Kofoed et al.   NATURE

Induction of human β-defensin-2 in pulmonary epithelial cells by Legionella pneumophila: involvement of TLR2 and TLR5, p38 MAPK, JNK, NF-κB, and AP-1

(2010) Stefanie Scharf et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

NOD1 and NOD2 regulation of pulmonary innate immunity to Legionella pneumophila

(2010) William R. Berrington et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

The pattern recognition receptors Nod1 and Nod2 account for neutrophil recruitment to the lungs of mice infected with Legionella pneumophila

(2010) Mariana S. Frutuoso et al.   MICROBES AND INFECTION

Caspase-1-induced pyroptosis is an innate immune effector mechanism against intracellular bacteria

(2010) Edward A Miao et al.   NATURE IMMUNOLOGY

Restriction of Legionella pneumophila Replication in Macrophages Requires Concerted Action of the Transcriptional Regulators Irf1 and Irf8 and Nod-Like Receptors Naip5 and Nlrc4

(2009) A. Fortier et al.   INFECTION AND IMMUNITY

Asc and Ipaf Inflammasomes Direct Distinct Pathways for Caspase-1 Activation in Response to Legionella pneumophila

(2009) C. L. Case et al.   INFECTION AND IMMUNITY

The role of biofilms and protozoa inLegionellapathogenesis: implications for drinking water

(2009) H.Y. Lau et al.   JOURNAL OF APPLIED MICROBIOLOGY

Identification of Host Cytosolic Sensors and Bacterial Factors Regulating the Type I Interferon Response to Legionella pneumophila

(2009) Kathryn M. Monroe et al.   PLoS Pathogens

Differential requirement for the activation of the inflammasome for processing and release of IL-1  in monocytes and macrophages

(2008) M. G. Netea et al.   BLOOD

Multiple MyD88-dependent responses contribute to pulmonary clearance ofLegionella pneumophila

(2008) Kristina A. Archer et al.   CELLULAR MICROBIOLOGY

Critical function for Naip5 in inflammasome activation by a conserved carboxy-terminal domain of flagellin

(2008) Karla L Lightfield et al.   NATURE IMMUNOLOGY