Article
Virology
Elena Percivalle, Irene Cassaniti, Mattia Calzolari, Davide Lelli, Fausto Baldanti
Summary: Phleboviruses transmitted by sandflies in the Mediterranean basin, such as TOSV and SFVs, can cause a range of symptoms in humans from asymptomatic to neuro-invasive infections. Despite gaps in knowledge, the infections are often underestimated by physicians. Further research and increased awareness of these viruses is crucial for effective diagnosis and treatment.
Article
Medicine, General & Internal
Muluemebet Kassa Mezen, Getasew Assefa Lemlem, Yemisrach Belete Biru, Abebaw Mengesha Yimer
Summary: This population-based study conducted in the North Wollo zone of Ethiopia found that the civil war led to the destruction of healthcare facilities and resulted in nearly 60% of children in the area being undervaccinated or unvaccinated. Stakeholders should collaborate to address the humanitarian crisis and improve the accessibility of healthcare services.
Article
Public, Environmental & Occupational Health
Novel Teklemuz, Mekonnen Sisay, Lemlem Daniel Baffa, Berhanu Mengistu, Azeb Atenafu
Summary: Utilization of growth monitoring and promotion services in children younger than 2 years in the West Armachiho district was low, with a utilization rate of 13.7%. Factors such as maternal educational status, institutional delivery, family size, access to health facility, and maternal knowledge were significantly associated with the utilization of these services.
FRONTIERS IN PUBLIC HEALTH
(2023)
Article
Microbiology
Zhengyi Zhu, Qi Yu, Ganggang Qi, Jufei Yang, Yinghua Ni, Wenhua Ruan, Luo Fang
Summary: This study assessed tooth discoloration in patients <8 years old after exposure to tigecycline, a derivative of tetracycline. It found that two patients developed yellow discoloration. However, due to the small sample size and inadequate follow-up period, the incidence and extent of tigecycline-associated dental adverse events remain unclear.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
(2021)
Article
Medicine, General & Internal
Flor M. Munoz, Lawrence D. Sher, Charu Sabharwal, Alejandra Gurtman, Xia Xu, Nicholas Kitchin, Stephen Lockhart, Robert Riesenberg, Joanna M. Sexter, Hanna Czajka, Grant C. Paulsen, Yvonne Maldonado, Emmanuel B. Walter, Kawsar R. Talaat, Janet A. Englund, Uzma N. Sarwar, Caitlin Hansen, Martha Iwamoto, Chris Webber, Luke Cunliffe, Benita Ukkonen, Silvina N. Martinez, Barbara A. Pahud, Iona Munjal, Joseph B. Domachowske, Kena A. Swanson, Hua Ma, Kenneth Koury, Susan Mather, Claire Lu, Jing Zou, Xuping Xie, Pei-Yong Shi, David Cooper, Oezlem Tuereci, Ugur Sahin, Kathrin U. Jansen, William C. Gruber
Summary: This study investigated the safety, immunogenicity, and efficacy of the BNT162b2 vaccine in children aged 6 months to 11 years. The results demonstrated that a three-dose series of 3-μg BNT162b2 was safe, immunogenic, and effective in children aged 6 months to 4 years.
NEW ENGLAND JOURNAL OF MEDICINE
(2023)
Letter
Medicine, General & Internal
Michael Fang, Elizabeth Selvin
Summary: This study utilizes 2021 National Health Interview Survey data to investigate the extent to which insulin rationing is prevalent among adults under the age of 65 in the United States, focusing on demographic characteristics.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
(2023)
Article
Medicine, General & Internal
Pier Mannuccio Mannucci, Alessia Antonella Galbussera, Barbara D'Avanzo, Mauro Tettamanti, Giuseppe Remuzzi, Ida Fortino, Olivia Leoni, Sergio Harari, Alessandro Nobili
Summary: Using the administrative database of Lombardy Welfare directorate, this study compared the first and subsequent waves of COVID-19 in the region. The results showed an increasing trend in the number of infected cases and a decreasing trend in the crude mortality rate. The study confirms a significant decline in public health and healthcare outcomes across the four waves in Lombardy.
INTERNAL AND EMERGENCY MEDICINE
(2023)
Article
Gastroenterology & Hepatology
Dominic King, Tom Thomas, Joht Singh Chandan, Nij Bhala, Nicola J. Adderley, Krishnarajah Nirantharakumar, Nigel Trudgill
Summary: The study indicates that there is an association between achalasia and autoimmune conditions as well as atopic conditions, particularly in patients under 40 years of age. These findings support an autoimmune etiology in achalasia and also suggest a potential atopic etiology, especially in younger subjects.
AMERICAN JOURNAL OF GASTROENTEROLOGY
(2021)
Article
Infectious Diseases
Tommaso Stroffolini, Alessia Ciancio, Alessandro Federico, Rosa G. Benigno, Guido Colloredo, Anna Lombardi, Rosa Cotugno, Gabriella Verucchi, Luigina Ferrigno, Federico Gioli, Massimo Marignani, Yulia Troshina, Mario Romeo, Francesco Di Costanzo, Grazia Anna Niro, Lorenzo Badia
Summary: Few reports have evaluated pneumococcal vaccination status in cirrhotic patients and there is no available data for European countries. A study conducted in Italy found that the vaccination coverage for cirrhotic patients was generally low, with lack of information being the main reason for not getting vaccinated.
EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES
(2023)
Article
Medicine, General & Internal
Daniela Penz, Elisabeth Waldmann, Monika Hackl, Lena Jiricka, Lisa-Maria Rockenbauer, Irina Gessl, Jasmin Zessner-Spitzenberg, Arnulf Ferlitsch, Michael Trauner, Monika Ferlitsch
Summary: The incidence of colorectal cancer is increasing among younger adults. This study analyzed data from a national screening colonoscopy registry in Austria to examine the prevalence of precursor lesions and the incidence of colorectal cancer in different age groups. The results showed an increase in the prevalence of adenomas and advanced adenomas in all age groups, while the incidence of colorectal cancer decreased among individuals older than 50 years.
Article
Radiology, Nuclear Medicine & Medical Imaging
R. Edward Hendrick, Mark A. Helvie, Debra L. Monticciolo
Summary: Breast cancer mortality rates among U.S. women have been declining since 1989, but the decline has stopped for women under 40 since 2010. The rapid increase in distant-stage breast cancer rates may be a contributing factor to the change in mortality trends for women under 40.
Review
Oncology
Sergio M. Lucchini, Agustin Esteban, Mariana A. Nigra, Ana T. Palacios, Juan P. Alzate-Granados, Hernan F. Borla
Summary: A systematic review of 661 patients from 38 studies found that patients with endometrial cancer who underwent hysteroscopic resection followed by progestogens agent treatment had better complete response, higher pregnancy rates, and lower rates of hysterectomies.
GYNECOLOGIC ONCOLOGY
(2021)
Article
Oncology
Qi Liu, Ruoxin Zhang, Qingguo Li, Xinxiang Li
Summary: The study found that non-biological factors (NBFs) are associated with the prognosis of colorectal cancer patients under 45 years old, with county-level median household income, marital status, and insurance status showing significant correlation with cause-specific survival.
FRONTIERS IN ONCOLOGY
(2021)
Article
Orthopedics
Chun-Jui Weng, Cheng-Pang Yang, Wen-Ling Yeh, Kuo-Yao Hsu, Shih-Sheng Chang, Chih-Hao Chiu, Alvin Chao-Yu Chen, Yi-Sheng Chan
Summary: This study compared the outcomes of ACL reconstruction between patients over 50 years and patients under 30 years old. The results showed comparable clinical and functional outcomes in both age groups, with a high rate of return to sports activity and a low rate of complications at the two-year follow-up. The younger group had a higher Tegner score after the surgery.
ORTHOPAEDIC JOURNAL OF SPORTS MEDICINE
(2022)
Article
Multidisciplinary Sciences
Jana Kozakova, Pavla Krizova, Marek Maly
Summary: The study analyzed the impact of PCV vaccination on the incidence of IPD in children under 5 years old in the Czech Republic. Results showed a significant decrease in IPD incidence after PCV vaccination, but ongoing surveillance is important to monitor for potential serotype replacement.