Does prolonged β-lactam infusions improve clinical outcomes compared to intermittent infusions? A meta-analysis and systematic review of randomized, controlled trials

Outcome Reporting Among Drug Trials Registered in ClinicalTrials.gov

(2013) Florence T. Bourgeois   ANNALS OF INTERNAL MEDICINE

Prolonged β-Lactam Infusion for Gram-negative Infections

(2011) Pranita D. Tamma et al.   PEDIATRIC INFECTIOUS DISEASE JOURNAL

Efficacy and safety of intravenous infusion of doripenem versus imipenem in ventilator-associated pneumonia: A multicenter, randomized study*

(2009) Jean Chastre et al.   CRITICAL CARE MEDICINE

A systematic review on clinical benefits of continuous administration of β-lactam antibiotics*

(2009) Jason A. Roberts et al.   CRITICAL CARE MEDICINE

The clinical consequences of antimicrobial resistance

(2009) Louis B Rice   CURRENT OPINION IN MICROBIOLOGY

Outcomes of extended infusion piperacillin/tazobactam for documented Gram-negative infections

(2009) Gita Wasan Patel et al.   DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE

Clinical cure of ventilator-associated pneumonia treated with piperacillin/tazobactam administered by continuous or intermittent infusion

(2009) Leonardo Lorente et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Optimizing bactericidal exposure for β-lactams using prolonged and continuous infusions in the pediatric population

(2009) Joshua D. Courter et al.   PEDIATRIC BLOOD & CANCER

Hospital resource utilization with doripenem versus imipenem in the treatment of ventilator-associated pneumonia

(2008) Sanjay Merchant et al.   CLINICAL THERAPEUTICS

Evaluation of area under the inhibitory curve (AUIC) and time above the minimum inhibitory concentration (T>MIC) as predictors of outcome for cefepime and ceftazidime in serious bacterial infections

(2008) Peggy S. McKinnon et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS