Article
Dermatology
Sharon Baum, Itai Atar, Dan Coster, Sara Dovrat, Michal Solomon, Eli Sprecher, Tal Zeeli, Aviv Barzilai
Summary: This retrospective cohort study aimed to compare the characteristics of pemphigus vulgaris patients with positive and negative herpes simplex virus. The results showed that patients with positive herpes simplex virus had significantly elevated levels of inflammatory markers and disease activity. Routine testing for herpes simplex virus in pemphigus vulgaris patients is necessary.
ACTA DERMATO-VENEREOLOGICA
(2022)
Article
Ophthalmology
Elif Akbas Ulman, Ozlem Barut Selver, Elif Demirkilinc Biler, Melis Palamar
Summary: The aim of this study was to assess the clinical features, recurrence rates, and effects on visual acuity in pediatric herpes simplex virus keratitis. Records of pediatric patients with herpes simplex virus keratitis between January 2012 and September 2021 were evaluated. The study found that stromal keratitis is the most common corneal manifestation in childhood and is often associated with corneal scarring, residual astigmatism, and amblyopia. The recurrence rate increases in the presence of immunosuppression.
Article
Oncology
Hyunjung Lee, Gopal K. Singh, Ahmedin Jemal, Farhad Islami
Summary: In this nationally representative study in the United States, adults living alone were found to have a higher risk of cancer death in several sociodemographic groups.
Article
Clinical Neurology
Yinong Young-Xu, Ethan Powell, Gabrielle M. Zwain, Mona T. Yazdi, Jiang Gui, Brian Shiner
Summary: This study investigated the association between symptomatic herpes simplex virus infection and dementia risk in a large US Veteran population and found that HSV infection was not associated with an increased risk of dementia. However, the use of antiherpetic medication was found to be significantly associated with a reduced risk of developing dementia, suggesting a potential protective effect. Further prospective studies are needed to confirm and explore this effect.
Letter
Medicine, Research & Experimental
Peter Bond
Summary: Pathogen burden is higher in Hispanic whites and black populations, as well as the poor and those without higher education, in the USA. The most frequent pathogen measured is Herpes simplex virus type 1 (HSV-1), which can weaken the immune system and damage the blood brain barrier. Prophylactic treatment targeting HSV-1 could be crucial in fighting against COVID-19.
MEDICAL HYPOTHESES
(2021)
Article
Immunology
Michael A. Hansen, Rodrigo Hasbun
Summary: Herpes simplex encephalitis (HSE) readmissions are relatively common, particularly among older and sicker individuals. Early signs and symptoms of neurological disease at index were correlated with encephalopathic specific readmissions.
CLINICAL INFECTIOUS DISEASES
(2022)
Article
Critical Care Medicine
Lina Jeantin, Claire Dupuis, Geoffroy Vellieux, Pierre Jaquet, Etienne de Montmollin, Jean-Francois Timsit, Romain Sonneville
Summary: The presence of absence of EEG reactivity to auditory/noxious stimuli is an independent predictor of poor functional outcome in severe herpes simplex encephalitis.
ANNALS OF INTENSIVE CARE
(2023)
Article
Medicine, General & Internal
Yonghong Li, Carmen H. Tong, Lance A. Bare, James J. Devlin
Summary: In this cohort study, SARS-CoV-2 seropositivity was not associated with low levels of vitamin D independently of other risk factors.
Article
Geriatrics & Gerontology
Beatriz Prado Noronha, Juliana Vaz de Melo Mambrini, Karen Cecilia Lima Torres, Olindo Assis Martins-Filho, Andrea Teixeira-Carvalho, Maria Fernanda Lima-Costa, Sergio Viana Peixoto
Summary: The study identified a high prevalence of CMV and HSV-1 infections in older adults, with different chemokines associated with antibody titers for each infection. Higher concentrations of certain chemokines were linked to lower or higher antibody titers for CMV, while intermediate levels of other chemokines were associated with higher antibody titers for both CMV and HSV-1.
EXPERIMENTAL GERONTOLOGY
(2021)
Article
Critical Care Medicine
Rajat Suri, James Macinko, Moira Inkelas, Jack Needleman
Summary: This study examines the impact of insurance status and the Affordable Care Act (ACA) on asthma outcomes for low-income adults aged 18 to 64. The results show that having health insurance is associated with improved asthma outcomes, and this relationship is mediated by cost barriers to medication and physician visits. While the ACA resulted in changes in insurance status, it did not significantly affect asthma outcomes. Cost barriers to medication and physician visits still persist in the insured population, which may explain the lack of improvement in asthma control at the population level.
Article
Infectious Diseases
Laura Vandervore, Eugenie Van Mieghem, Vicky Nowe, Sofie Schouwers, Charlotte Steger, Pascale Abrams, Jozef Van Schaeren, Anissa Meskal, Timon Vandamme
Summary: Differentiating COVID-19 from other causes of viral pneumonia can be complicated by immunoassay interference. The study found a significant correlation between HSV IgM positivity and SARS-CoV-2 IgM/IgG positivity. The addition of polyvinylpyrrolidone can reduce interference.
DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE
(2022)
Article
Immunology
Anna Jakobsen, Marie Thaarup Skov, Lykke Larsen, Pelle Trier Petersen, Christian Brandt, Lothar Wiese, Birgitte Ronde Hansen, Hans Rudolf Luettichau, Malte Mose Tetens, Jannik Helweg-Larsen, Merete Storgaard, Henrik Nielsen, Jacob Bodilsen
Summary: This study investigates the clinical presentation and prognostic factors of HSV-2 meningitis using a database from departments of infectious diseases in Denmark from 2015 to 2020. The results show that meningitis is common in younger women and unfavorable outcome at discharge is common, but it is not associated with sex, age, immunocompromise, or cerebrospinal fluid leukocyte count.
CLINICAL INFECTIOUS DISEASES
(2022)
Article
Sport Sciences
Billy Michael Ray, Kyle J. Kelleran, James E. Eubanks, Nan Nan, Changxing Ma, Derek Miles
Summary: This study aimed to assess the relationship between physical activity (PA) and pain, and also examine the prevalence of pain, PA levels, health care seeking behaviors, and impact of pain on daily activities and work. The results showed that individuals who met the PA guidelines had lower odds of reporting pain and engagement in PA decreased with higher pain frequency.
MEDICINE & SCIENCE IN SPORTS & EXERCISE
(2023)
Article
Immunology
Chad Poloni, Moshe Szyf, David Cheishvili, Christos M. Tsoukas
Summary: Age is a risk factor for infectious disease susceptibility and poor vaccine responses. Our findings suggest that CMV status plays a role in compromised immunity in older adults, as indicated by differences in epigenetic age and immune dysregulation.
JOURNAL OF INFECTIOUS DISEASES
(2022)
Article
Endocrinology & Metabolism
Gaoxiang Wang, Ze-Bin Fang, De-Liang Liu, Shu-Fang Chu, Hui-Lin Li, Heng-Xia Zhao
Summary: The study found that there was no significant association between caffeine intake and lumbar BMD overall, but significant correlations were observed in participants aged 30-39 and 40-49. In females, there was a positive correlation between lumbar BMD and higher coffee consumption, while in males aged 40-49, there was a negative correlation between coffee consumption and lumbar BMD.
FRONTIERS IN ENDOCRINOLOGY
(2022)
Article
Public, Environmental & Occupational Health
Ayden I. Scheim, Amaya G. Perez-Brumer, Greta R. Bauer
LANCET PUBLIC HEALTH
(2020)
Editorial Material
Public, Environmental & Occupational Health
Greta R. Bauer, Daniel J. Lizotte
AMERICAN JOURNAL OF PUBLIC HEALTH
(2021)
Article
Health Care Sciences & Services
Ayden Scheim, Greta R. Bauer, Joao L. Bastos, Tonia Poteat
Summary: This study aims to evaluate and validate the InDI in English and Spanish to determine whether attributions should be included. By using qualitative and quantitative research methods, bilingual measures of discrimination will be provided for multiple health disparity populations.
JMIR RESEARCH PROTOCOLS
(2021)
Review
Public, Environmental & Occupational Health
Greta R. Bauer, Siobhan M. Churchill, Mayuri Mahendran, Chantel Walwyn, Daniel Lizotte, Alma Angelica Villa-Rueda
Summary: A characterization of quantitative research applications of intersectionality from 1989 to mid-2020 revealed challenges in applying intersectionality theoretical frameworks in quantitative research, with about one in four articles failing to define intersectionality and about one in six including intersectional position components not reflective of social power. Quantitative methods were found to be simplistic and often misapplied or misinterpreted, highlighting the need for further work in understanding key features of quantitative intersectionality analyses and improving reporting practices.
SSM-POPULATION HEALTH
(2021)
Article
Pediatrics
Greta R. Bauer, Margaret L. Lawson, Daniel L. Metzger
Summary: Although the hypothesis of rapid onset gender dysphoria was proposed based on parental data, the results from adolescent clinical data did not support this hypothesis.
JOURNAL OF PEDIATRICS
(2022)
Review
Psychiatry
Greta R. Bauer, Mayuri Mahendran, Chantel Walwyn, Mostafa Shokoohi
Summary: In this study, the researchers reviewed English-language quantitative studies that explicitly stated an intersectional approach and used clustering methods, identifying 16 eligible studies out of 782. The methods primarily used latent class analysis, latent profile analysis, and clustering methods to describe social differences between groups or predict outcomes. It was noted that the rationales for method choices included both theoretical/intersectional and statistical arguments.
SOCIAL PSYCHIATRY AND PSYCHIATRIC EPIDEMIOLOGY
(2022)
Editorial Material
Medicine, General & Internal
Greta Bauer
Summary: Most biomedical research is flawed, but resources to highlight the strengths of weak studies are lacking. The BOGUS initiative aims to address this gap by providing guidelines for reporting underwhelming studies more accurately and effectively, ultimately improving the overall quality of research reporting.
BMJ-BRITISH MEDICAL JOURNAL
(2021)
Letter
Pediatrics
Greta R. Bauer, Margaret L. Lawson, Daniel L. Metzger
JOURNAL OF PEDIATRICS
(2022)
Article
Public, Environmental & Occupational Health
Mayuri Mahendran, Daniel Lizotte, Greta R. Bauer
Summary: Intersectionality recognizes that individual's multiple social positions or identities can interact to affect health outcomes. This study aimed to advance methods in intersectional estimation of binary outcomes in descriptive health disparities research. The results support the adoption of an intersectional approach to descriptive epidemiology.
SSM-POPULATION HEALTH
(2022)
Article
Health Care Sciences & Services
Jose M. Navarro, Ayden Scheim, Greta R. Bauer
Summary: This study examines the factors associated with postpandemic virtual care preferences in transgender and nonbinary communities. The results show that age, chronic health conditions, and level of support for gender identity or expression are associated with preferences for virtual or in-person care. The findings highlight the complexity of virtual care preferences and suggest the need for flexibility in meeting the specific health needs of transgender and nonbinary patients.
JOURNAL OF MEDICAL INTERNET RESEARCH
(2022)
Article
Public, Environmental & Occupational Health
Monica A. Ghabrial, Ayden I. Scheim, Caiden Chih, Heather Santos, Noah James Adams, Greta R. Bauer
Summary: Due to structural transphobia, TNB individuals were vulnerable to the negative effects of social isolation and financial instability resulting from COVID-19. The study found that change in finances and access to TNB peer gatherings interacted with baseline depression scores to predict depression symptoms during the pandemic. Therefore, multifaceted programs and services, including financial support and meaningful TNB community engagement, are needed to address health equity barriers posed by gender oppression.
Article
Urology & Nephrology
Jason Hallarn, Greta R. Bauer, Emery Potter, Hannah Wilcox, Jacy Newfeld, Yonah Krakowsky, Jacques Ravel, Jessica L. Prodger
Summary: This study aimed to describe gynecological concerns and vaginal care practices among transfeminine individuals who have undergone vaginoplasty. The results showed that transfeminine individuals reported a range of gynecological concerns outside of the surgical healing period. Various genital practices/exposures were identified, but no clear associations between practices/exposures and symptoms were found.
JOURNAL OF SEXUAL MEDICINE
(2023)
Article
Public, Environmental & Occupational Health
Greta R. Bauer, Mayuri Mahendran, Jessica Braimoh, Sejutie Alam, Siobhan Churchill
CANADIAN JOURNAL OF PUBLIC HEALTH-REVUE CANADIENNE DE SANTE PUBLIQUE
(2020)
Article
Public, Environmental & Occupational Health
Rebecca Gormley, Sally Y. Lin, Allison Carter, Valerie Nicholson, Kath Webster, Ruth Elwood Martin, M-J Milloy, Neora Pick, Terry Howard, Lu Wang, Alexandra de Pokomandy, Mona Loutfy, Angela Kaida
Article
Social Sciences, Interdisciplinary
Allison Carter, Sophie Patterson, Mary Kestler, Alexandra de Pokomandy, Catherine Hankins, Becky Gormley, Valerie Nicholson, Melanie Lee, Lu Wang, Saara Greene, Mona Loutfy, Angela Kaida
SEXUALITY RESEARCH AND SOCIAL POLICY
(2020)