A new computational strategy for predicting essential genes

Duplication and Retention Biases of Essential and Non-Essential Genes Revealed by Systematic Knockdown Analyses

(2013) Shane Woods et al.   PLoS Genetics

Younger Genes Are Less Likely to Be Essential than Older Genes, and Duplicates Are Less Likely to Be Essential than Singletons of the Same Age

(2012) W.-H. Chen et al.   MOLECULAR BIOLOGY AND EVOLUTION

Prioritizing candidate disease genes by network-based boosting of genome-wide association data

(2011) I. Lee et al.   GENOME RESEARCH

eggNOG v3.0: orthologous groups covering 1133 organisms at 41 different taxonomic ranges

(2011) S. Powell et al.   NUCLEIC ACIDS RESEARCH

OGEE: an online gene essentiality database

(2011) Wei-Hua Chen et al.   NUCLEIC ACIDS RESEARCH

The Pfam protein families database

(2011) M. Punta et al.   NUCLEIC ACIDS RESEARCH

The Global Transcriptional Response of Fission Yeast to Hydrogen Sulfide

(2011) Xu Jia et al.   PLoS One

Defining the Role of Essential Genes in Human Disease

(2011) Jonathan E. Dickerson et al.   PLoS One

Identifying essential genes in bacterial metabolic networks with machine learning methods

(2010) Kitiporn Plaimas et al.   BMC Systems Biology

Analysis of a genome-wide set of gene deletions in the fission yeast Schizosaccharomyces pombe

(2010) Dong-Uk Kim et al.   NATURE BIOTECHNOLOGY

Investigating the predictability of essential genes across distantly related organisms using an integrative approach

(2010) Jingyuan Deng et al.   NUCLEIC ACIDS RESEARCH

Dynamic Transcriptional and Metabolic Responses in Yeast Adapting to Temperature Stress

(2010) Katrin Strassburg et al.   OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY

Genotype to Phenotype: A Complex Problem

(2010) R. D. Dowell et al.   SCIENCE

New Genes in Drosophila Quickly Become Essential

(2010) S. Chen et al.   SCIENCE

Creation of a Bacterial Cell Controlled by a Chemically Synthesized Genome

(2010) D. G. Gibson et al.   SCIENCE

Towards the prediction of essential genes by integration of network topology, cellular localization and biological process information

(2009) Marcio L Acencio et al.   BMC BIOINFORMATICS

Computational prediction of essential genes in an unculturable endosymbiotic bacterium, Wolbachia of Brugia malayi

(2009) Alexander G Holman et al.   BMC MICROBIOLOGY

The universal distribution of evolutionary rates of genes and distinct characteristics of eukaryotic genes of different apparent ages

(2009) Y. I. Wolf et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The complex relationship of gene duplication and essentiality

(2009) Takashi Makino et al.   TRENDS IN GENETICS

Are essential genes really essential?

(2009) Michael A. D’Elia et al.   TRENDS IN MICROBIOLOGY

Topological properties of protein interaction networks from a structural perspective

(2008) Attila Gursoy et al.   BIOCHEMICAL SOCIETY TRANSACTIONS