Journal
JOURNAL OF CLINICAL MICROBIOLOGY
Volume 53, Issue 9, Pages 3039-3041Publisher
AMER SOC MICROBIOLOGY
DOI: 10.1128/JCM.01457-15
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Funding
- Ministry of Health, Labor, and Welfare, Japan
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The impact of the HCV genotype 1b core amino acid (aa) 70 mutant on the cumulative rate of hepatocellular carcinoma following eradication of HCV RNA by antiviral therapy was investigated with the Q-Invader assay. Multivariate analysis based on 649 patients indicated that a core aa70 Q-Invader mutant level >= 20% is a predictor of hepatocellular carcinoma.
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