Next-generation DNA sequencing-based assay for measuring allelic expression imbalance (AEI) of candidate neuropsychiatric disorder genes in human brain

Alzheimer's disease

(2011) Clive Ballard et al.   LANCET

Genetic Vulnerability and Susceptibility to Substance Dependence

(2011) Laura Jean Bierut   NEURON

Dopamine Transporter Gene Variant Affecting Expression in Human Brain is Associated with Bipolar Disorder

(2011) Julia K Pinsonneault et al.   NEUROPSYCHOPHARMACOLOGY

Schizophrenia Genetics: Where Next?

(2011) Y. Kim et al.   SCHIZOPHRENIA BULLETIN

Genome-wide assessment of imprinted expression in human cells

(2011) Lisanne Morcos et al.   GENOME BIOLOGY

High-throughput analysis of candidate imprinted genes and allele-specific gene expression in the human term placenta

(2010) Caroline Daelemans et al.   BMC GENETICS

Genetic validation of whole-transcriptome sequencing for mapping expression affected by cis-regulatory variation

(2010) Tomas Babak et al.   BMC GENOMICS

Nicotinic α5 receptor subunit mRNA expression is associated with distant 5′ upstream polymorphisms

(2010) Ryan M Smith et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

RNA sequencing reveals the role of splicing polymorphisms in regulating human gene expression

(2010) E. Lalonde et al.   GENOME RESEARCH

Effects of cis-regulatory variation differ across regions of the adult human brain

(2010) F. Buonocore et al.   HUMAN MOLECULAR GENETICS

Allele-specific DNA methylation: beyond imprinting

(2010) B. Tycko   HUMAN MOLECULAR GENETICS

Whole-genome association mapping of gene expression in the human prefrontal cortex

(2010) C Liu et al.   MOLECULAR PSYCHIATRY

Understanding mechanisms underlying human gene expression variation with RNA sequencing

(2010) Joseph K. Pickrell et al.   NATURE

Genome-wide allele-specific analysis: insights into regulatory variation

(2010) Tomi Pastinen   NATURE REVIEWS GENETICS

The Genetics of Alzheimer Disease: Back to the Future

(2010) Lars Bertram et al.   NEURON

Heritable Individual-Specific and Allele-Specific Chromatin Signatures in Humans

(2010) R. McDaniell et al.   SCIENCE

Genetic Control of Human Brain Transcript Expression in Alzheimer Disease

(2009) Jennifer A. Webster et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Allele-specific expression assays using Solexa

(2009) Bradley J Main et al.   BMC GENOMICS

Detection, Validation, and Downstream Analysis of Allelic Variation in Gene Expression

(2009) D. C. Ciobanu et al.   GENETICS

Genome-wide analysis of allelic expression imbalance in human primary cells by high-throughput transcriptome resequencing

(2009) Graham A. Heap et al.   HUMAN MOLECULAR GENETICS

Multiple Functional Variants in cis Modulate PDYN Expression

(2009) C. C. Babbitt et al.   MOLECULAR BIOLOGY AND EVOLUTION

Global patterns of cis variation in human cells revealed by high-density allelic expression analysis

(2009) Bing Ge et al.   NATURE GENETICS

Digital RNA allelotyping reveals tissue-specific and allele-specific gene expression in human

(2009) Kun Zhang et al.   NATURE METHODS

Genetics of human gene expression: mapping DNA variants that influence gene expression

(2009) Vivian G. Cheung et al.   NATURE REVIEWS GENETICS

New insights into the genetics of addiction

(2009) Ming D. Li et al.   NATURE REVIEWS GENETICS

Mapping complex disease traits with global gene expression

(2009) William Cookson et al.   NATURE REVIEWS GENETICS

Narrowing the Boundaries of the Genetic Architecture of Schizophrenia

(2009) N. R. Wray et al.   SCHIZOPHRENIA BULLETIN

A Robust Approach to Identifying Tissue-Specific Gene Expression Regulatory Variants Using Personalized Human Induced Pluripotent Stem Cells

(2009) Je-Hyuk Lee et al.   PLoS Genetics

Targeted screening of cis-regulatory variation in human haplotypes

(2008) D. J. Verlaan et al.   GENOME RESEARCH

A HapMap harvest of insights into the genetics of common disease

(2008) Teri A. Manolio et al.   JOURNAL OF CLINICAL INVESTIGATION

Genome-wide analysis of transcript isoform variation in humans

(2008) Tony Kwan et al.   NATURE GENETICS

Identification of genetic variants using bar-coded multiplexed sequencing

(2008) David W Craig et al.   NATURE METHODS

Mapping and quantifying mammalian transcriptomes by RNA-Seq

(2008) Ali Mortazavi et al.   NATURE METHODS

Psychiatric genetics: progress amid controversy

(2008) Margit Burmeister et al.   NATURE REVIEWS GENETICS

RNA-Seq: a revolutionary tool for transcriptomics

(2008) Zhong Wang et al.   NATURE REVIEWS GENETICS

A GSTM3 polymorphism associated with an etiopathogenetic mechanism in Alzheimer disease

(2008) Olivier C. Maes et al.   NEUROBIOLOGY OF AGING

A Functional Haplotype Implicated in Vulnerability to Develop Cocaine Dependence is Associated with Reduced PDYN Expression in Human Brain

(2008) Vadim Yuferov et al.   NEUROPSYCHOPHARMACOLOGY

Polymorphisms affecting gene transcription and mRNA processing in pharmacogenetic candidate genes: detection through allelic expression imbalance in human target tissues

(2008) Andrew D. Johnson et al.   Pharmacogenetics and Genomics

Differential Allelic Expression in the Human Genome: A Robust Approach To Identify Genetic and Epigenetic Cis-Acting Mechanisms Regulating Gene Expression

(2008) David Serre et al.   PLoS Genetics