Article
Agriculture, Dairy & Animal Science
N. R. B. Consolo, V. L. M. Buarque, J. Silva, M. D. Poleti, L. C. G. S. Barbosa, A. Higuera-Padilla, J. F. M. Gomez, L. A. Colnago, D. E. Gerrard, A. Saran Netto, S. L. Silva
Summary: This study investigated metabolite profiling in liver and muscle of Nellore males with low or high residual feed intake to identify physiological changes. Results showed that different metabolic compounds in liver and muscle correlated with energy, protein, and fat metabolism, affecting residual feed intake and carcass traits in the animals.
ANIMAL FEED SCIENCE AND TECHNOLOGY
(2021)
Article
Agriculture, Dairy & Animal Science
Ludmilla C. Brunes, Fernando Baldi, Fernando B. Lopes, Raysildo B. Lobo, Rafael Espigolan, Marcos F. O. Costa, Nedenia B. Stafuzza, Claudio U. Magnabosco
Summary: A weighted single-step genome-wide association study in Nellore cattle identified candidate genes and functional pathways related to feed efficiency traits. These genes are involved in various metabolic and physiological pathways, contributing to a better understanding of the genetic and physiological mechanisms regulating feed efficiency in Nellore cattle.
JOURNAL OF ANIMAL BREEDING AND GENETICS
(2021)
Article
Biotechnology & Applied Microbiology
Kai Wang, Shujie Wang, Xiang Ji, Dong Chen, Qi Shen, Yang Yu, Weihang Xiao, Pingxian Wu, Jun Yuan, Yiren Gu, Guoqing Tang
Summary: This study conducted a genome-wide association study for feed conversion ratio (FCR) and residual feed intake (RFI) in Yorkshire pigs using whole-genome sequencing data. They identified novel SNPs associated with FCR and RFI and identified candidate genes related to these traits.
Article
Agriculture, Dairy & Animal Science
M. H. Lidauer, E. Negussie, E. A. Mantysaari, P. Mantysaari, S. Kajava, T. Kokkonen, A. Chegini, T. Mehtio
Summary: In this study, a new metric called regression on expected feed intake (ReFI) was introduced to evaluate the efficiency of feed utilization in dairy cows. Compared to other metrics such as residual feed intake (RFI) and genetic residual feed intake (gRFI), ReFI showed higher genetic variation and heritability in measuring feed efficiency. Selection based on ReFI breeding values resulted in higher milk production and a greater increase in efficiency compared to selection based on RFI or gRFI values.
Article
Multidisciplinary Sciences
Leandro Sannomiya Sakamoto, Luana Lelis Souza, Sarah Bernardes Gianvecchio, Matheus Henrique Vargas de Oliveira, Josineudson Augusto I. I. de Vasconcelos Silva, Roberta Carrilho Canesin, Renata Helena Branco, Melissa Baccan, Alexandre Berndt, Lucia Galvao de Albuquerque, Maria Eugenia Zerlotti Mercadante
Summary: The study evaluated the relationship between performance, residual feed intake (RFI), and enteric methane emissions in growing Nellore cattle. It was found that more efficient animals consumed less dry matter and emitted less methane, but the emissions per unit of consumed dry matter and the percentage of gross energy lost as methane were higher for more efficient animals.
Article
Agriculture, Dairy & Animal Science
Thales de Lima Silva, Cedric Gondro, Pablo Augusto de Souza Fonseca, Delvan Alves da Silva, Giovana Vargas, Haroldo Henrique de Rezende Neves, Ivan Carvalho Filho, Caio de Souza Teixeira, Lucia Galvao de Albuquerque, Roberto Carvalheiro
Summary: Testicular hypoplasia (TH) leads to economic losses and decreased efficiency in meat production systems. A genome-wide association study and functional analysis identified candidate genes, such as KHDRBS3, GPX5, STAR, and ERLIN2, that may play important roles in spermatogenesis, steroid synthesis, and lipid metabolism.
JOURNAL OF ANIMAL BREEDING AND GENETICS
(2023)
Article
Veterinary Sciences
Yue Liu, Hao Wu, Wanbao Chen, Chang Liu, Qingxiang Meng, Zhenming Zhou
Summary: This study investigated the relationships among rumen bacteria, rumen metabolites, and the residual feed intake (RFI) phenotype of beef cattle. The results showed that there were differences in the rumen bacterial composition and metabolites between different RFI phenotypes, which are potentially important for improving beef cattle feed efficiency.
FRONTIERS IN VETERINARY SCIENCE
(2022)
Article
Agriculture, Dairy & Animal Science
Kerry Houlahan, Flavio S. Schenkel, Dagnachew Hailemariam, Jan Lassen, Morten Kargo, John B. Cole, Erin E. Connor, Silvia Wegmann, Oliveira Junior, Filippo Miglior, Allison Fleming, Tatiane C. S. Chud, Christine F. Baes
Summary: This study demonstrates that direct selection on residual feed intake can improve feed efficiency in dairy cattle, leading to higher economic response and more favorable selection responses for production and feed efficiency. As selection pressure on residual feed intake increases over time, the selection responses for production, health, and fertility traits may become less favorable.
Article
Agriculture, Dairy & Animal Science
Pamela C. C. Machado, Luiz F. F. Brito, Rafaela Martins, Luis Fernando B. Pinto, Marcio R. R. Silva, Victor B. B. Pedrosa
Summary: This study investigated the associations between single nucleotide polymorphism and visual score traits in beef cattle. By analyzing genomic data and candidate genes, the researchers identified novel genomic regions and candidate genes associated with body conformation, precocity, and muscularity. The findings contribute to a better understanding of the molecular mechanisms involved in Zebu cattle growth and provide valuable information for selecting and breeding beef cattle with desired traits.
Article
Microbiology
Xiaonan Zhou, Ying Ma, Chaoyun Yang, Zhiyan Zhao, Yanling Ding, Yanfeng Zhang, Pengfei Wang, Lei Zhao, Chenglong Li, Zonghua Su, Xiaowei Wang, Wenxun Ming, Ling Zeng, Xiaolong Kang
Summary: A metagenome methodology was used to explore the characteristics of the rumen and fecal microbiota in beef cattle with different RFI. Bacteroidetes and Firmicutes were the dominant phyla in the rumen and feces. Prevotella was identified as a potential biomarker in the rumen of the low RFI group, while Turicibacter and Prevotella were potential biomarkers in the feces of the high RFI and low RFI groups, respectively. Functional annotation revealed differences in the ability of rumen microbiota to utilize dietary polysaccharides and dietary protein between the high RFI and low RFI groups. Association analysis showed significant correlations between rumen microbes and differentially expressed genes regulating RFI. The study suggests that microbial differences may play a critical role in regulating feed efficiency in beef cattle.
Article
Microbiology
Yue Liu, Chang Liu, Hao Wu, Qingxiang Meng, Zhenming Zhou
Summary: This study investigates the relationships among bacterial populations, microbial metabolites, and residual feed intake (RFI) phenotypes in the small intestine of beef cattle. The results reveal microbial and metabolite differences between different RFI groups, and identify several microorganisms that are associated with feed efficiency.
FRONTIERS IN MICROBIOLOGY
(2022)
Article
Agriculture, Dairy & Animal Science
R. Martins, L. F. Brito, P. C. Machado, L. F. B. Pinto, M. R. Silva, F. S. Schenkel, V. B. Pedrosa
Summary: This study identified genomic regions associated with fatness in Nellore cattle and elucidated metabolic pathways related to phenotypic expression. Twenty genes related to fatness were found on 11 chromosomes, explaining 12.96% of total additive genetic variance. Additionally, novel candidate genes were detected, which could provide further knowledge on genetic regions associated with carcass fatness in beef cattle.
Article
Biotechnology & Applied Microbiology
Lucio F. M. Mota, Samuel W. B. Santos, Gerardo A. Fernandes Junior, Tiago Bresolin, Maria E. Z. Mercadante, Josineudson A. V. Silva, Joslaine N. S. G. Cyrillo, Fabio M. Monteiro, Roberto Carvalheiro, Lucia G. Albuquerque
Summary: Multi-trait weighted GWAS and meta-analysis identified genomic regions associated with feed efficiency-related traits in beef cattle, highlighting the importance of physiological mechanisms related to energy metabolism and hypothalamus signaling.
Article
Agriculture, Dairy & Animal Science
Antonio M. Silvestre, Ana Carolina J. Pinto, Werner F. Schleifer, Lidiane S. Miranda, Leandro A. F. Silva, Daniel M. Casali, Katia L. R. Souza, Vanessa G. L. Gasparini, Gustavo D. Cruz, Garret Suen, Danilo D. Millen
Summary: This study examined the relationship between rumen microbial community, rumen morphometrics, feeding behavior, feedlot performance, and carcass characteristics of Nellore cattle classified by residual feed intake (RFI). The results showed that the ruminal microbial community was not affected by different levels of RFI, suggesting that the differences in feed efficiency of Nellore cattle are associated with other factors.
Article
Fisheries
Wenchao Yu, Shihai Gong, Yisha Lu, Yawei Shen, Junyu Liu, Zekun Huang, Xuan Luo, Weiwei You, Caihuan Ke
Summary: In this study, a genome-wide association study (GWAS) was conducted to explore the genetic basis of feed efficiency (FE) traits in Pacific abalone. Significant SNPs associated with feed efficiency ratio (FER) and residual feed intake (RFI) were identified, and candidate genes involved in biological processes related to FER and RFI were identified. Furthermore, an overlapped gene associated with RFI was identified through comparative transcriptomic analyses. This study provides valuable insights into the genetics of abalone FE and offers potential SNPs for molecular marker selection and breeding.
Article
Veterinary Sciences
Guilherme Henrique Gebim Polizel, Rafael Espigolan, Paulo Fantinato-Neto, Ricardo de Francisco Strefezzi, Raissa Braido Rangel, Cynthia de Carli, Aricia Christofaro Fernandes, Evandro Fernando Ferreira Dias, Roberta Cavalcante Cracco, Miguel Henrique de Almeida Santana
Summary: This study examined the impact of different prenatal nutrition approaches on reproductive and nutrigenetic traits of male offspring during the finishing phase. The findings suggest a genotype-environment interaction among the different prenatal treatments, with the FP treatment showing a higher incidence of major sperm defects compared to the NP treatment.
VETERINARY RESEARCH COMMUNICATIONS
(2023)
Article
Chemistry, Applied
Leandro Neodini Remedio, Vitor Augusto dos Santos Garcia, Arina Lazaro Rochetti, Andresa Aparecida Berretta, Cristiana Maria Pedroso Yoshida, Heidge Fukumasu, Fernanda Maria Vanin, Rosemary Aparecida de Carvalho
Summary: The effect of incorporating green propolis ethanol extract (GPEE) into hydroxypropyl methylcellulose (HPMC) using the printing technique was evaluated in this study. The properties of the printed films were characterized and the results showed that the number of printed layers affected the film properties. The films with GPEE exhibited anti-inflammatory activity.
FOOD HYDROCOLLOIDS
(2023)
Article
Multidisciplinary Sciences
Laercio R. Porto-Neto, Pamela A. Alexandre, Nicholas J. Hudson, John Bertram, Sean M. McWilliam, Andre W. L. Tan, Marina R. S. Fortes, Michael R. McGowan, Ben J. Hayes, Antonio Reverter
Summary: Worldwide, the identification and selection of fertile bulls plays a crucial role in beef production. In this study, fertility-related phenotypes and high-density DNA genotypes were collected for thousands of bulls from six tropical breeds, revealing both genetic correlations and the importance of breed representation for accurate genomic estimated breeding values. Several candidate genes associated with bull fertility traits were identified, contributing to early-life selection and genetic improvement strategies. This study also enhances our knowledge of the molecular basis of male fertility in mammals.
Article
Agriculture, Dairy & Animal Science
Beatriz Batista Trigo, Natalia Fonseca Alves, Marco Milanesi, Jose Fernando Garcia, Endashaw Terefe, Olivier Hanotte, Abdulfatai Tijjani, Yuri Tani Utsunomiya
Summary: A structural variant (SV1) in the agouti signaling protein gene (ASIP) has been found to be strongly associated with hair coat darkness in specific regions of zebu cattle from the Nellore breed. Analysis of whole-genome sequences of zebu and taurine cattle revealed that ASIP-SV1 is commonly found in 45.9% of zebu cattle and 6.3% of taurine cattle, with the taurine cattle showing zebu introgression or being from crossbreeding. This study provides evidence of the widespread presence of ASIP-SV1 in both zebu populations and taurine cattle with zebu admixture.
Article
Biotechnology & Applied Microbiology
Felipe E. Carvalho, Jose Bento S. Ferraz, Victor B. Pedrosa, Elisangela C. Matos, Joanir P. Eler, Marcio R. Silva, Jose D. Guimaraes, Fernando O. Bussiman, Barbara C. A. Silva, Fernando A. Cancado, Henrique A. Mulim, Rafael Espigolan, Luiz F. Brito
Summary: Given the economic importance of fertility and reproductive traits in the beef cattle industry, understanding their genetic background and developing effective breeding strategies are crucial. This study estimated variance components, heritability, and genetic correlations for fertility, female precocity, and semen production and quality traits in Nellore cattle using genomic information. The findings highlight the heritability and genetic relationships among these traits, providing valuable information for breeding programs to improve reproductive performance in Nellore cattle.
Review
Oncology
Andrigo Barboza De Nardi, Cristina de Oliveira Massoco Salles Gomes, Carlos Eduardo Fonseca-Alves, Felipe Noleto de Paiva, Lais Calazans Menescal Linhares, Gabriel Joao Unger Carra, Rodrigo dos Santos Horta, Felipe Augusto Ruiz Sueiro, Paulo Cesar Jark, Adriana Tomoko Nishiya, Carmen Helena de Carvalho Vasconcellos, Rodrigo Ubukata, Karen Batschinski, Renata Afonso Sobral, Simone Crestoni Fernandes, Luiz Roberto Biondi, Ricardo De Francisco Strefezzi, Julia Maria Matera, Marcelo Monte Mor Rangel, Denner Santos dos Anjos, Carlos Henrique Maciel Brunner, Renee Laufer-Amorim, Karine Germano Cadrobbi, Juliana Vieira Cirillo, Mauro Caldas Martins, Nazilton de Paula Reis Filho, Diego Fernando Silva Lessa, Roberta Portela, Carolina Scarpa Carneiro, Silvia Regina Ricci Lucas, Heidge Fukumasu, Marcus Antonio Rossi Feliciano, Juliany Gomes Quitzan, Maria Lucia Zaidan Dagli
Summary: Hemangiosarcoma is a malignant tumor that originates in the endothelial cells of blood vessels. It can be classified as non-visceral and visceral types based on the location of origin. This article provides data on the epidemiology, etiology, diagnosis, staging, therapeutic modalities, and prognosis of canine hemangiosarcoma based on a consensus meeting organized by the Brazilian Association of Veterinary Oncology (ABROVET) in September 2022.
Article
Agriculture, Dairy & Animal Science
Joedson Dantas Goncalves, Jose Bento Sterman Ferraz, Flavio Vieira Meirelles, Ricardo Perecin Nociti, Maria Emilia Franco Oliveira
Summary: Our study compared the mechanisms of cervical dilation in sheep and cows in different phases of the reproductive cycle. We found differences in gene expression between the follicular and luteal phases in both species. The PI3K/Akt pathway was identified as an important mechanism in cervical relaxation.
Article
Biochemistry & Molecular Biology
Guilherme Henrique Gebim Polizel, Aricia Christofaro Fernandes, Edison Furlan, Barbara Carolina Teixeira Prati, Jose Bento Sterman Ferraz, Miguel Henrique de Almeida Santana
Summary: This study examined how maternal nutrition affects the plasma metabolome of Nellore bulls during the rearing and finishing phases, as well as the metabolic differences between these phases. Three nutritional approaches were used for 126 cows during pregnancy. Blood samples were collected from male offspring during the rearing and finishing phases. Targeted metabolome analysis was performed on the plasma samples. Significant metabolites were identified between treatments and over time. No significant metabolic pathways were found in the finishing phase, but significant pathways were found in the rearing phase. Therefore, prenatal nutrition has an impact on the plasma metabolome of bulls, and different production stages affect the metabolic levels of bulls.
Article
Agriculture, Dairy & Animal Science
Thiago Kan Nishimura, Amanda Guimaraes da Silva, Gabriela Abitante, Carl Robertson Dahlen, Rodrigo Silva Goulart, German Dario Ramirez Zamudio, Saulo Luz Silva, Miguel Henrique de Almeida Santana, Arlindo Saran Netto, Paulo Roberto Leme, Guilherme Pugliesi
Summary: This study evaluated the effects of early weaning on body composition, hormone concentrations, metabolites, and reproductive performance of Nelore cows. The results showed that early weaning at 150 days can successfully recover the cow's body condition and improve the pregnancy success rate in the next breeding season, regardless of the cow's parity order.
JOURNAL OF ANIMAL SCIENCE
(2023)
Article
Physics, Multidisciplinary
S. Athira, Saulo L. L. Silva, Probal Nag, Sushma Lakshmi, C. Sharath Kumar, Debendra Prasad Panda, Sayan Das, Sarita Rajput, Andrews P. Alex, A. Sundaresan, Sivaranjana Reddy Vennapusa, T. Maitra, D. Jaiswal-Nagar
Summary: In this paper, the authors used the distance between the states as a theoretical measure to determine the bipartite entanglement in a one-dimensional magnetic dimer system. The calculation was compared with the concurrence, a well-known entanglement measure, and found to be the same. Experimental verification was done on single crystals of copper acetate, showing the existence of bipartite entanglement even at room temperature. Characterization and calculations revealed the weak intermolecular interactions and low probability of direct Cu-Cu exchange in copper acetate.
NEW JOURNAL OF PHYSICS
(2023)
Article
Agriculture, Dairy & Animal Science
Mario L. Santana, Annaiza B. Bignardi, Rodrigo J. Pereira, Gerson A. Oliveira Junior, Anielly P. Freitas, Roberto Carvalheiro, Joanir P. Eler, Jose B. S. Ferraz, Joslaine N. S. G. Cyrillo, Maria E. Z. Mercadante
Summary: The prenatal environment can affect the performance of cattle. The offspring of cows in a better gestation environment show better productive and reproductive performances. Genetic merit can vary depending on the gestational environment. Genomic regions that affect economic traits in cattle were identified. Breeders should consider the genotype by prenatal environment interaction and provide proper care for pregnant cows.
Article
Biochemistry & Molecular Biology
Caroline Procopio de Oliveira, Barbara Maria Frigieri, Heidge Fukumasu, Luiz Gustavo de Almeida Chuffa, Adriana Alonso Novais, Debora Aparecida Pires de Campos Zuccari
Summary: Melatonin shows a protective effect in the clinical treatment of canine mammary tumors by modulating EV-mediated signaling.
Article
Veterinary Sciences
Roberta Cavalcante Cracco, Isabela Modolo Ruy, Guilherme Henrique Gebim Polizel, Aricia Christofaro Fernandes, Edison Furlan, Geovana Camila Baldin, Gianluca Elmi Chagas Santos, Miguel Henrique de Almeida Santana
Summary: This study examined the effects of different prenatal nutrition treatments on pregnant cows and their calves. The results showed minimal impact of prenatal nutrition on the calves' weaning weight and growth rates.
VETERINARY SCIENCES
(2023)
Article
Biotechnology & Applied Microbiology
David Astudillo-Barraza, Romulo Oses, Carlos Henriquez-Castillo, Clemente Michael Vui Ling Wong, Jose M. Perez-Donoso, Cristina Purcarea, Heidge Fukumasu, Natalia Fierro-Vasquez, Pablo A. A. Perez, Paris Lavin
Summary: The Antarctic Streptomyces fildesensis produces ethyl acetate extract (EAE) fractions with antimicrobial activity against foodborne bacteria and multi-resistant strains. These fractions contain actinomycin-like compounds that exhibit antiproliferative activity against human tumor cell lines. The compounds induce apoptosis and alter cell morphology, indicating their potential as novel anticancer agents.
FERMENTATION-BASEL
(2023)
