Article
Gastroenterology & Hepatology
Fabiana Zingone, Erica Secchettin, Ilaria Marsilio, Flavio Valiante, Valerio Zorzetto, Giovanni Cataudella, Anna D'Odorico, Cristina Canova
Summary: The study aimed to describe the profiles of adult patients with newly diagnosed celiac disease (CeD) and their association with quality of life and psychological symptoms. Results showed that symptomatic presentation, diagnostic delay, and gender may affect quality of life and psychological disorders in CeD patients.
DIGESTIVE AND LIVER DISEASE
(2021)
Article
Nutrition & Dietetics
Claudia Chaves, Antonio Raposo, Renata Puppin Zandonadi, Eduardo Yoshio Nakano, Fernando Ramos, Edite Teixeira-Lemos
Summary: The aim of this study was to evaluate the quality of life (QoL) perception of Portuguese celiac patients. A cross-sectional study was conducted using an online self-administered celiac disease quality of life questionnaire (CDQ). The results showed that the Portuguese CDQ was reliable and responsive in assessing the QoL of Portuguese celiac patients. Factors such as age at diagnosis, educational level, compliance with a gluten-free diet, and use of antidepressants had an impact on different domains of QoL. This data is essential for developing strategies to improve the physical, emotional, and social well-being of celiac patients, and for future comparative research among celiac populations from different countries.
Article
Nutrition & Dietetics
Ana Luisa Falcomer, Priscila Farage, Claudia B. Pratesi, Riccardo Pratesi, Lenora Gandolfi, Eduardo Yoshio Nakano, Antonio Raposo, Renata Puppin Zandonadi
Summary: The study revealed that during the COVID-19 pandemic, the quality of life (QoL) of Brazilian individuals with celiac disease (CD) was more affected by gastrointestinal aspects, but overall the pandemic did not have a negative impact on their QoL. Individuals not following a gluten-free diet and those using antidepressants experienced a larger burden and diminished QoL. Further research is needed to understand how the duration of the pandemic will affect celiac individuals and compare outcomes to periods before and after COVID-19.
Article
Health Care Sciences & Services
Azza A. El-Housseiny, Farah A. Alsadat, Najlaa M. Alamoudi, Osama M. Felemban, Rana H. Mosli, Omar Saadah
Summary: This study assessed the oral health-related quality of life (OHRQoL) in children with celiac disease (CD) compared to healthy controls. The results showed that children with CD had poorer OHRQoL, with a significant association between OHRQoL scores and recurrent aphthous stomatitis (RAS), as well as lower parental income and education.
QUALITY OF LIFE RESEARCH
(2022)
Editorial Material
Medicine, General & Internal
James O'Connell, Joseph A. Murray, Katri Kaukinen
Summary: This article discusses a patient presenting with heartburn symptoms and a family history of celiac disease, offering different viewpoints on whether to recommend a gluten-free diet.
NEW ENGLAND JOURNAL OF MEDICINE
(2021)
Review
Public, Environmental & Occupational Health
Zhaoli Tang, Almea Matanock, Seonghye Jeon, Andrew J. Leidner
Summary: This study reviewed the literature and developed pooled quality-adjusted life-year (QALY) estimates associated with pneumococcal disease states. The findings indicated disparities in QOL estimates associated with pneumococcal disease in the literature. Pooled estimates provide a consistent source for future modeling efforts.
JOURNAL OF PUBLIC HEALTH
(2022)
Article
Medicine, General & Internal
Eyayaw Ashete Belachew, Gashaw Sisay Chanie, Eshetie Gizachew, Ashenafi Kibret Sendekie
Summary: This study assessed the health-related quality of life (HRQoL) and its determinants among patients with psoriasis. The results showed that several factors including gender, use of alternative therapy, duration of disease, duration on medication, presence of comorbidity, and income were significantly associated with poor HRQoL. In conclusion, psoriasis patients have reduced HRQoL and interventions targeting these factors are essential to preserve their HRQoL.
FRONTIERS IN MEDICINE
(2023)
Review
Gastroenterology & Hepatology
Benjamin Lebwohl, Alberto Rubio-Tapia
Summary: The incidence of celiac disease is increasing due to both improved recognition and a real increase of the disorder. The reasons for this true rise are unclear, but may be related to environmental factors. Early-life gluten exposure is a major focus of prevention efforts.
Article
Gastroenterology & Hepatology
Pasquale Mansueto, Gabriele Spagnuolo, Silvia Calderone, Carmela Cinzia D'Agate, Salvatore Cosenza, Giuseppe Leonardi, Salvatore Camilleri, Mirco Pistone, Giovanna Seminara, Carlo Alaimo, Maurizio Soresi, Antonio Carroccio, Serena Garufi
Summary: This study retrospectively evaluated the data of 369 patients with CD from the Sicilian Network and found that non-classical CD presentation was more common, there was a diagnostic delay of approximately 9 years, most patients did not undergo multiple duodenal biopsies, and 59.9% of the patients received unrecommended CD serology assays.
DIGESTIVE AND LIVER DISEASE
(2022)
Article
Health Care Sciences & Services
Zeinab Nikniaz, Mohammad Asghari Jafarabadi, Mahdieh Abbasalizad Farhangi, Masood Shirmohammadi, Leila Nikniaz
Summary: The study using SEM found that in Iranian patients with celiac disease, HRQOL was influenced by age, education level, adherence to a gluten-free diet, and GSRS score. Additionally, occupation and disease duration were associated with HRQOL only in women and men respectively.
HEALTH AND QUALITY OF LIFE OUTCOMES
(2021)
Article
Gastroenterology & Hepatology
Fahdah F. Al-sunaid, Maha M. Al-homidi, Rawan M. Al-qahtani, Reema A. Al-ashwal, Ghada A. Mudhish, Mahitab A. Hanbazaza, Abeer S. Al-zaben
Summary: The study found that a significant proportion of individuals with CD adhere to a gluten-free diet, but also face food insecurity. There is a significant association between adherence to a gluten-free diet and food insecurity, and food insecurity can impact the mental and emotional health of individuals with CD.
BMC GASTROENTEROLOGY
(2021)
Article
Health Care Sciences & Services
Monique M. Germone, Merlin Ariefdjohan, Marisa Stahl, Mary Shull, Pooja Mehta, Sadie Nagle, Sally Tarbell, Edwin Liu
Summary: This study evaluates the impact of celiac disease (CD) and the gluten-free diet (GFD) on the health-related quality of life (HRQoL) in children with CD in the United States. The results show that CD significantly affects the HRQoL of both children and their caregivers. Screening for HRQoL in this population can help identify patients and families in need of additional support.
QUALITY OF LIFE RESEARCH
(2022)
Article
Multidisciplinary Sciences
Shahid Shah, Ghulam Abbas, Ayesha Aslam, Fawad Ahmad Randhawa, Faiz Ullah Khan, Haris Khurram, Usman Rashid Chand, Muhammad Hammad Butt, Tauqeer Hussain Mallhi, Yusra Habib Khan
Summary: This study aimed to assess the health-related quality of life (HRQoL) of patients with obesity, hypertension (HTN) and type 2 diabetes (T2D), individually and in combination. A questionnaire-based cross-sectional study was conducted in Punjab, Pakistan. The findings showed that these diseases individually reduced HRQoL, and the presence of multiple diseases had a more detrimental impact on HRQoL.
Article
Endocrinology & Metabolism
Daniel Weiman, Farid H. Mahmud, Antoine B. M. Clarke, Esther Assor, Charlotte McDonald, Fred Saibil, Heather A. Lochnan, Zubin Punthakee, Margaret A. Marcon
Summary: This study found that the adoption of a GFD in T1D patients with asymptomatic CD did not significantly affect HRQoL and SPW, but worsened with symptom onset and increased HbA(1c). The findings suggest that the transition to a GFD can be successfully made in this population without adversely impacting quality of life.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
(2021)
Article
Nursing
Harith Eranga Yapa, Louise Purtell, Shirley Chambers, Ann Bonner
Summary: This study aimed to compare symptoms and health-related quality of life in chronic kidney disease patients and found that as kidney function deteriorated, symptoms worsened and health-related quality of life decreased. Early identification and proactive management by nurses are crucial for reducing symptom burden and improving quality of life in these patients.
JOURNAL OF CLINICAL NURSING
(2021)
Article
Pediatrics
Fredrik Norstrom, Fredinah Namatovu, Annelie Carlsson, Lotta Hogberg, Anneli Ivarsson, Anna Myleus
Summary: The study found no significant associations between parents' education level and occupation with coeliac disease prevalence, suggesting that parental socioeconomic status is not a reliable indicator for identifying children at higher risk of coeliac disease.
Article
Clinical Neurology
Ryan G. Wagner, Fredrik Norstrom, Melanie Y. Bertram, Stephen Tollman, Lars Forsgren, Charles R. Newton, Lars Lindholm
Summary: The study analyzed the cost-effectiveness of deploying community health workers to improve epilepsy treatment adherence in rural South Africa using a Markov model. The results showed that this intervention was cost-effective and had the potential to reduce the treatment gap for epilepsy in rural areas of South Africa.
Article
Gastroenterology & Hepatology
Fredrik Norstrom, Anna Myleus, Katrina Nordyke, Annelie Carlsson, Lotta Hogberg, Olof Sandstrom, Lars Stenhammar, Anneli Ivarsson, Lars Lindholm
Summary: Research indicates that conducting mass screening for coeliac disease can effectively lower diagnosis delay, and is cost-effective at a threshold of 50,000 Euro per gained QALY.
BMC GASTROENTEROLOGY
(2021)
Article
Geriatrics & Gerontology
Magnus Zingmark, Fredrik Norstrom
Summary: Baseline distributions and transitions over time between levels of dependency among older persons after being granted social care in a Swedish municipality were described descriptively and analysed with survival analysis. Older people in Sweden being allocated home help are at high risk for decline towards higher levels of dependency, especially those at mild or moderate dependency levels at baseline. It is important for municipalities to implement cost-effective preventative interventions for older people at an early stage before a decline toward increasing levels of dependency.
Article
Pediatrics
Olof Sandstrom, Fredrik Norstrom, Annelie Carlsson, Lotta Hogberg, Maria van der Palz, Lars Stenhammar, Charlotta Webb, Anneli Ivarsson, Anna Myleus
Summary: The study found a high risk of conversion to coeliac disease among those with potential disease within 5 years, while individuals with a negative serological screening had a very low risk of being clinically diagnosed during the follow-up period.
ARCHIVES OF DISEASE IN CHILDHOOD
(2022)
Review
Cardiac & Cardiovascular Systems
Panduleni Penipawa Shimanda, Stefan Soderberg, Scholastika Ndatinda Iipinge, Ebba Mwalundouta Neliwa, Fenny Fiindje Shidhika, Fredrik Norstrom
Summary: This study aimed to estimate the prevalence of rheumatic heart disease (RHD) and assess the related healthcare systems in Namibia. The findings suggest a lower prevalence of clinically diagnosed RHD in Namibia, with a higher impact on young people and a concentration of cases in the northeastern regions. The study also identified weaknesses in the healthcare systems, including lack of patient unique identifiers, missing data, and inadequate clinic-based prevention activities.
BMC CARDIOVASCULAR DISORDERS
(2022)
Article
Health Care Sciences & Services
Fredrik Norstrom, Anne Hammarstrom
Summary: The study examines the relationship between unemployment and health, focusing on the sensitivity of estimates based on different measurements of unemployment and statistical models. The results highlight the importance of how unemployment is measured in estimating the relationship between unemployment and health. The choice of statistical model has minimal impact on the estimates, except for the inclusion of a variable measuring health status before becoming unemployed.
BMC MEDICAL RESEARCH METHODOLOGY
(2022)
Article
Psychiatry
Fredrik Norstrom, Lisbeth Slunga Jarvholm, Therese Eskilsson
Summary: This study aimed to explore the healthcare utilization, health-related quality of life, work ability, sick leave level, and psychological measures of patients with stress-induced exhaustion disorder before, during, and after a multi-modal rehabilitation (MMR) program. The results showed an increase in healthcare consumption during MMR, with residual health problems remaining after the program.
Article
Health Care Sciences & Services
Sun Sun, Ling-Hsiang Chuang, Klas-Goran Sahlen, Lars Lindholm, Fredrik Norstrom
Summary: This study aims to establish a value set based on EQ-VT for EQ-5D-5L to support decision-making in Sweden. Various models were tested using c-TTO and DCE data, with the preferred model being the heteroskedastic model based on the c-TTO data. The value set can be used in economic evaluations for reimbursement decision making in Sweden.
HEALTH AND QUALITY OF LIFE OUTCOMES
(2022)
Article
Pediatrics
Mara Cerqueiro Bybrant, Elsa Palmkvist, Hanna Soderstrom, Marie Lindgren, Hans Hildebrand, Fredrik Norstrom, Annelie Carlsson
Summary: This study investigated whether there was a difference in the prevalence of coeliac disease in children with type 1 diabetes born during and after the Swedish coeliac epidemic. The study found no significant difference in the prevalence of coeliac disease among children with type 1 diabetes between the two cohorts.
Article
Public, Environmental & Occupational Health
Fredrik Norstrom, Magnus Zingmark, Anita Pettersson-Stromback, Klas-Goran Sahlen, Malin Ohrling, Karin Bolenius
Summary: This study investigates the relationship between workload, health-related quality of life, and work distribution preferences among home care workers in Sweden. It found that higher workloads were associated with tasks such as responding to personal alarms, running errands, rehabilitation, and help with bathing. Personnel preferred to spend less time responding to personal alarms and more time providing social support.
INTERNATIONAL ARCHIVES OF OCCUPATIONAL AND ENVIRONMENTAL HEALTH
(2023)
Article
Endocrinology & Metabolism
Marie Lindgren, Elsa Palmkvist, Fredrik Norstrom, Mara Cerqueiro Bybrant, Anna Myleus, Ulf Samuelsson, Johnny Ludvigsson, Annelie Carlsson
Summary: In Sweden, there was a fourfold increase in the incidence of celiac disease in young children between 1985 and 1996. It was believed that the timing and amount of gluten introduced during infancy could explain this epidemic. A national register study compared the cumulative incidence of type 1 diabetes in two birth cohorts, and found that children born after the epidemic had a higher incidence of type 1 diabetes compared to those born during the epidemic.
ACTA DIABETOLOGICA
(2023)
Article
Health Care Sciences & Services
Xiaolei Hu, Karolina Jonzen, Olof A. Lindahl, Marcus Karlsson, Fredrik Norstrom, Erik Lundstrom, Katharina Stibrant Sunnerhagen
Summary: The study evaluated the feasibility and acceptability of Rehabkompassen as a digital follow-up tool for stroke patients in outpatient clinical settings. The results showed high feasibility and adherence of the study protocol, as well as high acceptability of Rehabkompassen among patients and physicians, indicating potential for a large definitive RCT.
JMIR HUMAN FACTORS
(2022)
Article
Medicine, Research & Experimental
Hanna Soderstrom, Matti Cervin, Jonatan Dereke, Magnus Hillman, Iren Tiberg, Fredrik Norstrom, Annelie Carlsson
Summary: The study found that children with newly diagnosed T1D showed better glycemic control after following a GFD, suggesting a positive effect of GFD on blood sugar control. However, the GFD group reported poorer quality of life. The findings should be interpreted with caution due to the small sample size and possible confounding effects.
CONTEMPORARY CLINICAL TRIALS COMMUNICATIONS
(2022)
