Article
Multidisciplinary Sciences
Izabela Steinka, Jadwiga Stankiewicz, Anita Kuku Lowicz, Aleksandra Wilczynska
Summary: This study assessed the inhibitory effects of macerates and juices derived from Viola tricolor and T. patula flower petals on Staphylococcus aureus. The results showed a low degree of inhibition, except for a synergistic effect observed when using both species' petals in the disc diffusion method.
Article
Food Science & Technology
Alicia Freitag, MacDonald Cluff, Arina C. Hitzeroth, Lize van Wyngaardt, Arno Hugo, Celia J. Hugo
Summary: The study found that gradually lowering salt content in certain food products may have a negative impact on food safety and shelf-life. Experimental results showed that potassium chloride treatment was more effective in controlling the growth of microbial communities compared to treatments with no added salt. Higher salt content may reduce the functional diversity of microbial communities and E. coli in Boerewors.
LWT-FOOD SCIENCE AND TECHNOLOGY
(2021)
Article
Microbiology
Sabina T. Kenesheva, Setshaba Taukobong, Sergey V. Shilov, Tatyana V. Kuznetsova, Ardak B. Jumagaziyeva, Tatyana A. Karpenyuk, Oleg N. Reva, Aleksandr I. Ilin
Summary: The antimicrobial activity of iodine-containing complexes may be influenced by the organic moiety of the complex, such as amino acids. Gene regulation and metabolic alterations were observed in multidrug-resistant microorganisms treated with iodine-containing complexes, suggesting disruption of cell wall integrity, DNA damage, and oxidative stress. The results shed light on the mechanisms and potential applications of iodine-containing complexes against antibiotic-resistant pathogens.
Article
Public, Environmental & Occupational Health
Khaled A. Noaman, Naiyf S. Alharbi, Jamal M. Khaled, Shine Kadaikunnan, Ahmed S. Alobaidi, Abeer O. Almazyed, Mohammed S. Aldosary, Saeed Al Rashedi
Summary: This study investigated the ability of gentamicin to induce small colony variants (SCVs) in E. coli ATCC 25922 and compared the genotypic and phenotypic changes and stress tolerance of these SCVs with clinical SCV E. coli and normal clinical E. coli isolates. The results showed that gradual exposure to sub-minimum inhibitory concentration (MIC) of gentamicin can induce mutation responsible for SCV formation and the evolution of multidrug-resistant (MDR) E. coli strains. The mutated SCVs exhibited high-level aminoglycoside resistance and developed resistance to cephalosporin antibiotics and aztreonam.
JOURNAL OF INFECTION AND PUBLIC HEALTH
(2023)
Article
Biochemistry & Molecular Biology
Yeseul Kim, Sanghun Kim, Kiu-Hyung Cho, Jin-Hyung Lee, Jintae Lee
Summary: Bacterial biofilm formation can be effectively inhibited by cinnamaldehyde and its derivatives, especially 4-nitrocinnamaldehyde. These compounds exhibit strong antibiofilm activities against UPEC and S. aureus, making them promising candidates for the treatment of biofilm-associated diseases.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Agriculture, Multidisciplinary
Zhang Hui-lin, Zhao Yi-yang, Zhou Zi-chong, Ding Huan-zhong
Summary: In this study, the susceptibility breakpoints of cefquinome against E. coli and S. aureus in pigs were determined, with low resistance rates observed. Pharmacokinetic/pharmacodynamic cut-off values were established, providing guidance for effective treatment of infections caused by these bacteria strains. Adjustment of dosing regimen showed increased effectiveness for S. aureus infections, highlighting the importance of surveillance and dosage guidance for cefquinome in pigs.
JOURNAL OF INTEGRATIVE AGRICULTURE
(2021)
Article
Microbiology
Ilya S. Korotetskiy, Sergey V. Shilov, Tatyana V. Kuznetsova, Aleksandr I. Ilin, Monique Joubert, Setshaba Taukobong, Oleg N. Reva
Summary: Iodine has been used as an antimicrobial agent with no reported resistance. Recent studies on iodine-containing nano-micelles show promising results against antibiotic-resistant pathogens. This study analyzed gene regulation in multi-drug-resistant reference strains treated with sublethal concentrations of iodine-containing drug FS-1, revealing species-specific alterations in gene expression profiles influenced by growth phase. The study sheds light on unexplored bioactivities of iodine and its antibacterial mechanisms, aiding in the future design of new drugs against antibiotic-resistant infections.
Article
Biochemistry & Molecular Biology
Viktoria Rungelrath, Frank R. DeLeo
Summary: Staphylococcus aureus is a major cause of bacterial infections worldwide, with resistance to antibiotics and the ability to evade host defenses. Research has identified certain virulence molecules of S. aureus as therapeutic targets. Treatment options for methicillin-resistant S. aureus are limited, highlighting the need for further research to develop new therapies.
ANTIOXIDANTS & REDOX SIGNALING
(2021)
Article
Materials Science, Multidisciplinary
C. Guerra, A. Ringuede, M. I. Azocar, M. Walter, C. Galarce, F. Bedioui, M. Cassir, M. Sancy
Summary: AISI 430 stainless steel is an attractive material for use in the healthcare industry, but shows clear signs of corrosion after two weeks of exposure in a sterile medium.
Article
Food Science & Technology
Hong Yan, Yingying Lu, Xin Li, Yanglei Yi, Xin Wang, Yuanyuan Shan, Bianfang Liu, Yuan Zhou, Xin Lu
Summary: Bacteriocin BM1829 has antimicrobial activity against both Gram-positive and Gram-negative bacteria, and exhibits good stability against various environmental factors. It can disrupt membrane integrity, arrest the cell cycle, and reduce bacterial populations during food storage, suggesting its potential as a food preservative or antibacterial agent.
Review
Microbiology
Vanessa Silva, Sara Araujo, Andreia Monteiro, Jose Eira, Jose Eduardo Pereira, Luis Maltez, Gilberto Igrejas, Teresa Semedo Lemsaddek, Patricia Poeta
Summary: Animal production involves the use of antimicrobial agents to promote growth and treat diseases, but it also leads to the emergence of antibiotic-resistant strains such as methicillin-resistant Staphylococcus aureus (MRSA). MRSA poses a significant threat to public health and animal welfare. Livestock-associated MRSA (LA-MRSA) was initially restricted to a specific clonal complex (CC398), but its diversity has increased over time, accompanied by multidrug resistance. This review summarizes the main clonal lineages of MRSA associated with different animals, including swine, cattle, rabbits, and poultry, and highlights the multidrug resistance patterns.
Article
Materials Science, Ceramics
Jose Domingo Trujillo-Casarreal, Jesus Morales-Jimenez, V Rodriguez-Gonzalez
Summary: Metallic nanoparticles (NPs) with size and morphology that enable a large surface-to-volume ratio exhibit antibacterial properties. The surface functionalization of copper sulfide NPs on mesoporous SiO2 spheres (PMSi) was successfully achieved. The antibacterial activity of PMSi loaded with sulfamethoxazole (SMX) against Escherichia coli and Staphylococcus aureus was studied. CuS and Cu functionalized on PMSi exhibited a good spectrum of antimicrobial activity against Gram-positive (S. aureus) and Gram-negative (E. coli) bacteria.
JOURNAL OF NON-CRYSTALLINE SOLIDS
(2023)
Article
Engineering, Environmental
Li-Ting Yen, Chih-Huang Weng, Nhu Anh Thi Than, Jing-Hua Tzeng, Astrid R. Jacobson, Kesinee Iamsaard, Van Dien Dang, Yao-Tung Lin
Summary: This study characterized the mode of inactivation of S. aureus and E. coli via biocalcium oxide (BCO) using various microscopy and spectroscopy techniques. The results demonstrated that BCO altered bacterial cell permeability, leading to sustained inactivation. BCO exhibited superior disinfection capacity compared to other shell-derived disinfectants, making it a cost-effective option for pathogen control.
CHEMICAL ENGINEERING JOURNAL
(2022)
Article
Pharmacology & Pharmacy
Aiman Batool, Mercy Bore, Jingwen Wu, Chaoyu Li, Hongjuan Zeng
Summary: The combination of silver nanoparticles and cefazolin can enhance the antibacterial effectiveness of cefazolin, exhibiting strong antibacterial activity against Escherichia coli and Staphylococcus aureus.
JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY
(2023)
Article
Microbiology
Yaoying Zeng, Qian Yu, Shujun Cheng
Summary: In this study, the biological pesticide Liangguoan demonstrated antibacterial activity against Staphylococcus aureus and Escherichia coli, with minimum inhibitory concentrations of 20 mg/mL and 40 mg/mL, respectively. The bactericide was found to inhibit the bacteria by disrupting cell structure and metabolism.
ARCHIVES OF MICROBIOLOGY
(2021)