Review
Clinical Neurology
Ning Liang, Yaxin Chen, Sihong Yang, Changhao Liang, Lidong Gao, Shang Wang, Yanping Wang, Zhanjun Zhang, Nannan Shi
Summary: This study found that Chinese Herbal Medicine, particularly Ginko leaf extracts, could help prevent cognitive decline and improve cognitive function and ability in daily living activities for individuals with mild cognitive impairment. Although the quality of the included trials was relatively low, these findings are still significant.
FRONTIERS IN NEUROLOGY
(2022)
Review
Chemistry, Medicinal
Mojgan Shavakhi, Amirhossein Sahebkar, Farinaz Shirban, Mohammad Bagherniya
Summary: This review indicates that herbal medicines have significant effects in reducing pain, ulcer size, and healing time in the treatment of recurrent aphthous stomatitis. Few adverse events were reported in the herbal treatment group, suggesting that medicinal plants and phytochemicals are effective and safe agents for RAS treatment.
PHYTOTHERAPY RESEARCH
(2022)
Review
Chemistry, Medicinal
Alireza Heiran, Kamran Bagheri Lankarani, Ryan Bradley, Alireza Simab, Mehdi Pasalar
Summary: Herbal remedies showed better improvement in symptoms and quality of life for patients with functional dyspepsia (FD) compared to placebo, with no significant differences in adverse events. Further high-quality studies are needed to firmly establish the clinical efficacy of herbal remedies.
PHYTOTHERAPY RESEARCH
(2022)
Review
Pharmacology & Pharmacy
Hongliang Xie, Aolin Zhang, Xuan Mou, Tao He, Junwei Li, Chi Chiu Wang, Xiaohui Fan, Lu Li
Summary: This study conducted a systematic review and meta-analysis on the efficacy and safety of Chinese herbal medicine (CHM) for threatened miscarriage. The findings suggested that CHM showed significant effects in maintaining pregnancy, increasing beta-hCG levels, and reducing Traditional Chinese medicine (TCM) syndrome severity. However, caution is needed in interpreting the results due to the low to moderate quality of the available evidence.
FRONTIERS IN PHARMACOLOGY
(2023)
Review
Pharmacology & Pharmacy
Qing Wang, Hui Ye, Qiu-qin Wang, Wei-tong Li, Bei-bei Yu, Ya-mei Bai, Gui-hua Xu
Summary: Chinese herbal medicine combined with chemotherapy shows significant improvements in white blood cell, neutrophil, hemoglobin, and platelet counts, as well as in Karnofsky performance scale score, without severe adverse events observed. High-quality randomized controlled trials with larger sample sizes are needed to further validate the efficacy and safety of this combination therapy for chemotherapy-induced leukopenia.
FRONTIERS IN PHARMACOLOGY
(2021)
Review
Chemistry, Medicinal
Hong Li, Jenny Manuela Kreiner, Ann Rann Wong, Mingdi Li, Yue Sun, Leyao Lu, Jianping Liu, Angela Wei Hong Yang
Summary: This systematic review found that oral Chinese herbal medicine may improve symptoms of allergic rhinitis and have advantages over Western medications in some aspects, but also has limitations. More large, multicenter, well-designed randomized controlled trials are needed in the future to validate the potential of Chinese herbal medicine for treating allergic rhinitis.
PHYTOTHERAPY RESEARCH
(2021)
Review
Integrative & Complementary Medicine
Si-jia Zhu, Rui-ting Wang, Ze-yu Yu, Ruo-xiang Zheng, Chang-hao Liang, You-you Zheng, Min Fang, Mei Han, Jian-ping Liu
Summary: This study reviewed 19 randomized controlled trials and found that 9 Chinese herbal medicines may help improve MG symptoms. Among them, Compound Huangqi may bring additional benefits in patients with MG. The herbal medicine groups had fewer adverse events compared to the control groups.
INTEGRATIVE MEDICINE RESEARCH
(2022)
Review
Pharmacology & Pharmacy
Ying Zhao, Hufang Zhou, Qingxuan Liu, Jialin Liu, Mengwei Wu, Siyuan Yuan, Weiwei Xu, Ying Wang, Kaiyue Wang, Lili Li, Jinmin Liu
Summary: The combination of Chinese Herbal Medicine and antiepileptic drugs can effectively reduce monthly seizure frequency and abnormal rate of electroencephalogram in patients with intractable epilepsy, while improving their quality of life and decreasing the occurrence of adverse events. However, the findings should be interpreted carefully due to the high or uncertain risk of bias in the included trials.
FRONTIERS IN PHARMACOLOGY
(2022)
Review
Pharmacology & Pharmacy
Ming Yang, Si-jia Zhu, Chen Shen, Rui Zhai, Duo-duo Li, Min Fang, Jing-nan Xu, Ye-na Gan, Lu Yang, Zhi-ying Ren, Ruo-xiang Zheng, Nicola Robinson, Jian-ping Liu
Summary: This study provides an overview of the clinical application of Chinese herbal injections in cancer care based on randomized controlled trials, systematic reviews, and meta-analyses. The most consistently reported benefits were observed for Compound Kushen, Shenqi Fuzheng, Aidi, and Kangai for tumor response, quality of life, myelosuppression, and enhancing immunity. Further evidence-based research is needed to inform clinical and policy decision-making in the use of these herbal injections for cancer treatment.
FRONTIERS IN PHARMACOLOGY
(2021)
Review
Plant Sciences
Shadi A. D. Mohammed, Liu Hanxing, Lu Fang, Adnan Mohammed Algradi, Mohammed Alradhi, Mohammed Safi, Liu Shumin
Summary: Integrated Chinese herbal medicine (CHM) and Western Medicine (WM) treatments have been used for primary hypertension (PHTN) patients in China. Randomized control trials (RCTs) have shown that combining Chinese with WM is effective and safe for PHTN, but there is insufficient evidence and no clear information available. This systematic study and meta-analysis aimed to evaluate the effectiveness and safety of CHM combined with WM in reducing blood pressure for patients with PHTN.
JOURNAL OF ETHNOPHARMACOLOGY
(2023)
Review
Pharmacology & Pharmacy
Hongfei Zhu, Mengting Li, Chen Tian, Honghao Lai, Yuqing Zhang, Jiaheng Shi, Nannan Shi, Hui Zhao, Kehu Yang, Hongcai Shang, Xin Sun, Jie Liu, Long Ge, Luqi Huang
Summary: Through a systematic review of randomized controlled trials and observational studies, this study found that Chinese herbal medicine (CHM) treatment is effective and safe for mild/moderate COVID-19 patients. CHM treatment can reduce the conversion rate to severe cases and mortality, shorten the time to symptom resolution, length of hospital stay, and time to viral clearance, and increase the rate of nucleic acid conversion.
FRONTIERS IN PHARMACOLOGY
(2022)
Review
Pharmacology & Pharmacy
Jie Wang, Yuhang Chen, Xinwei Yang, Jianli Huang, Yihua Xu, Wei Wei, Xianbo Wu
Summary: This review evaluated the therapeutic effects and safety of Chinese herbal medicine (CHM) for the treatment of chronic pruritus. Analysis of 24 randomized controlled trials showed that CHM treatment was more effective than Western medicine treatment in relieving symptoms. However, high-quality studies are needed to further validate these findings.
FRONTIERS IN PHARMACOLOGY
(2023)
Review
Integrative & Complementary Medicine
Ying Wang, Mei Han, Christopher E. Pedigo, Zhi-Min Xie, Wei-Jie Wang, Jian-Ping Liu
Summary: Evidence shows that Chinese herbal medicine has a significant beneficial effect on controlling disease activity and reducing glucocorticoid dosage in patients with SLE. Further research with advanced designed RCTs for treating moderate to severe SLE is urgently needed.
CHINESE JOURNAL OF INTEGRATIVE MEDICINE
(2021)
Review
Pharmacology & Pharmacy
Ji Hee Jun, Lin Ang, Tae Young Choi, Hye Won Lee, Myeong Soo Lee
Summary: The study found that integrative medicine, combining herbal medicine with drug therapy, is more effective in treating Behcet's disease, reducing recurrence rate and improving inflammatory markers.
Review
Integrative & Complementary Medicine
Ying Wang, Mei Han, Christopher E. Pedigo, Zhi-Min Xie, Wei-Jie Wang, Jian-Ping Liu
Summary: This study found that Chinese herbal medicine (CHM) has significant benefits in reducing disease activity and decreasing the dose of glucocorticoids among systemic lupus erythematosus (SLE) patients compared to placebo. Future advanced designed randomized controlled trials with multicenter and longer follow-up are urgently needed to further validate its clinical efficacy.
CHINESE JOURNAL OF INTEGRATIVE MEDICINE
(2021)
Review
Integrative & Complementary Medicine
Wen Bin Hou, Wei Jia Sun, Xiao Wen Zhang, Yuan Xi Li, You You Zheng, Yu Xin Sun, Jian Ping Liu, Zhao Lan Liu
Summary: This review assessed the effectiveness and safety of Five-flavor Sophora falvescens enteric-coated capsule (FSEC) for the treatment of ulcerative colitis (UC). The results showed that FSEC may be effective in UC treatment compared to conventional medicine, and its use does not increase the risk of adverse events. However, due to the limited number of clinical trials and low methodological quality, the findings should be interpreted with caution.
EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE
(2022)
Review
Integrative & Complementary Medicine
Bao-Yong Lai, Ai-Jing Chu, Bo-Wen Yu, Li-Yan Jia, Ying-Yi Fan, Jian-Ping Liu, Xiao-Hua Pei
Summary: This study systematically evaluated the effect and safety of compound Kushen injection (CKI) as an add-on treatment for breast cancer. The results showed that CKI plus chemotherapy had significant effects in improving treatment response rate, disease control rate, and quality of life, with a lower risk of adverse drug reactions compared to chemotherapy alone.
EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE
(2022)
Review
Plant Sciences
Ming Yang, Chen Shen, Si-jia Zhu, Yao Zhang, Hong-lin Jiang, Yu-dong Bao, Guo-yan Yang, Jian-ping Liu
Summary: Aidi injection has been shown to have adjuvant benefits in specific cancer treatments, primarily in improving survival rates, enhancing quality of life, and reducing the side effects of chemotherapy/radiotherapy. However, the evaluation of its effectiveness currently faces challenges in terms of methodological and reporting quality.
JOURNAL OF ETHNOPHARMACOLOGY
(2022)
Review
Integrative & Complementary Medicine
Shi-Bing Liang, Wen-Bin Hou, Ruo-Xiang Zheng, Chang-Hao Liang, Li-Jiao Yan, Hao-Nan Wang, Hui-Juan Cao, Mei Han, Nicola Robinson, Jian-Ping Liu
Summary: Compound glycyrrhizin injection may have adjuvant therapeutic effects in improving liver function for children with acute icteric hepatitis, showing superiority in reducing bilirubin, alanine aminotransferase, and aspartate transaminase levels when combined with conventional western medicine treatment. However, the evidence regarding its safety and overall therapeutic effects is currently limited and further well-designed randomized controlled trials are needed for verification.
INTEGRATIVE MEDICINE RESEARCH
(2022)
Review
Health Care Sciences & Services
Ning Dai, Qingyun He, Xuehan Liu, Min Fang, Min Xiong, Xun Li, Duoduo Li, Jianping Liu
Summary: This systematic review of randomized controlled trials (RCTs) found that therapeutic massage/Tuina has significant beneficial effects on functional dyspepsia (FD) patients. Tuina alone or in combination with conventional therapy improved overall symptoms and quality of life in FD patients.
QUALITY OF LIFE RESEARCH
(2023)
Article
Medicine, General & Internal
Guoyan Yang, Xun Li, Nicole Peel, Nerida Klupp, Jian-Ping Liu, Alan Bensoussan, Hosen Kiat, Dennis Chang
Summary: This study aimed to explore participants' perceptions of influential factors on their trial participation and adherence to a Tai Chi intervention within a trial setting. The results showed that internal and external motivation, positive feelings, benefits of Tai Chi, and future practice are important for trial participation and adherence. The role of the Tai Chi instructor(s) was found to be crucial.
PATIENT PREFERENCE AND ADHERENCE
(2022)
Article
Substance Abuse
Jingli Xing, Jianping Liu, Mei Han, Yue Jiang, Jiali Jiang, He Huang
Summary: There has been an upward trend in the number of academic publications on TCM therapy for smoking cessation from 2005 to 2021. China is the most productive country in this field, with Beijing University being the top institution. Wang Y is the dominant author contributing to TCM therapy for smoking cessation, with the highest H-Index. The most frequently cited journals are Evidence-Based Complementary and Alternative Medicines and the Chinese Journal of Clinical Rehabilitation. The keywords 'acupuncture', 'traditional Chinese medicine', 'colitis', 'hypertension', 'chronic obstructive pulmonary disease', 'risk factors', and 'alternative medicine' ranked highest in frequency. The diseases of concern for healthy people mainly include cardiovascular, cancer, diabetes, hypertension, and pregnancy, while the diseases of concern for patients mainly include cancer, diabetes, hematopathy, stroke, cardiovascular, diabetes, lung disease, and hypertension. The treatment methods mainly involve traditional Chinese medicine and acupuncture, and the research methods mainly include multi-center randomized controlled trials that are double-blind.
TOBACCO INDUCED DISEASES
(2022)
Review
Integrative & Complementary Medicine
Xiao-wen Zhang, Jing Li, Wen-bin Hou, Yue Jiang, Ruo-xiang Zheng, De-hao Xu, Chen Shen, Nicola Robinson, Jian-ping Liu
Summary: A systematic review of ten randomized controlled trials involving 732 HIV/AIDS patients found that Chinese herbal medicine (CHM) may improve liver function indices and effective rate for drug-induced liver injury (DILI). However, larger and high-quality trials are needed for further validation.
INTEGRATIVE MEDICINE RESEARCH
(2023)
Article
Integrative & Complementary Medicine
Xiao-Yang Hu, Ru-Yu Xia, Michael Moore, Beth Stuart, Ling-Zi Wen, Bertrand Graz, Lily Lai, Jian-Ping Liu, Yu -Tong Fei, Merlin Willcox
Summary: This study aimed to identify the use of various treatments and their association with the use of antibiotics and patient reported clinical recovery in Chinese adults with acute cough. An online survey was conducted to collect data on sociodemographic and clinical characteristics, treatments received, and perceived changes in symptoms among adults with recent acute cough. The study found a high proportion of inappropriate use of antibiotics for the treatment of simple acute cough.
INTEGRATIVE MEDICINE RESEARCH
(2023)
Article
Integrative & Complementary Medicine
Ruyu Xia, Xiaoyang Hu, Michael Moore, Beth Stuart, Lingzi Wen, Bertrand Graz, Jianping Liu, Merlin Willcox, Yutong Fei
Summary: Anti-microbial resistance is a global public health threat, and promoting effective alternative treatments such as Chinese herbal medicines (CHMs) can help reduce unnecessary antibiotic use. This study in China found that nearly 40% of participants with acute cough used CHMs, and the proportion of those who subsequently needed antibiotics was lower compared to other treatments.
EUROPEAN JOURNAL OF INTEGRATIVE MEDICINE
(2023)
Article
Integrative & Complementary Medicine
Chun-li Lu, Liu-qing Yang, Xue-han Liu, Xin-yan Jin, Fu-xiang Wang, Thomas Friedemann, Nicola Robinson, Sven Schroeder, Hong-zhou Lu, Jian-ping Liu
Summary: This study aims to verify the efficacy and safety of the Chinese herbal medicine Shufeng Jiedu Capsule (SFJD) in patients with mild and moderate COVID-19 infection. The study design is a randomized, blind, placebo control trial, and multiple outcome measures will be assessed including time to symptom alleviation, changes in inflammatory parameters, and lung inflammation.
EUROPEAN JOURNAL OF INTEGRATIVE MEDICINE
(2023)
Article
Integrative & Complementary Medicine
Xinyan Jin, Leqin Xu, Chunli Lu, Xue Xue, Xuehan Liu, Yuzhen Zhou, Xiaoyang Hu, Jianping Liu, Xiaohua Pei
Summary: During the COVID-19 pandemic, healthcare workers faced a heightened risk of infection. Traditional Chinese medicine (TCM) has been recommended as a preventative measure. This survey investigated the use of infection control behaviors, preventative measures, and outcomes among healthcare workers during the surge of Omicron variant infections.
EUROPEAN JOURNAL OF INTEGRATIVE MEDICINE
(2023)
Review
Medicine, General & Internal
Nibras Jasim, Darsiha Balakirishnan, Han Zhang, Genevieve Z. Steiner-Lim, Diana Karamacoska, Guo-Yan Yang
Summary: Tai Chi may have some benefits for people with early-stage dementia, but the effects on neurocognitive outcomes are still inconclusive. Further research is needed to understand the underlying mechanisms of Tai Chi and how it can be applied as an intervention to delay the progression of dementia.
SYSTEMATIC REVIEWS
(2023)
Review
Integrative & Complementary Medicine
Guoyan Yang, Wenyuan Li, Nerida Klupp, Huijuan Cao, Jianping Liu, Alan Bensoussan, Hosen Kiat, Diana Karamacoska, Dennis Chang
Summary: The study suggests that Tai Chi may have positive effects on psychological well-being and quality of life in people with cardiovascular disease and/or cardiovascular risk factors, and is safe for them to practice. However, more well-designed studies are needed to determine the effects and safety of Tai Chi on psychological well-being and quality of life in this population.
BMC COMPLEMENTARY MEDICINE AND THERAPIES
(2022)
