Inhibition by curcumin of multiple sites of the transforming growth factor-beta1 signalling pathway ameliorates the progression of liver fibrosis induced by carbon tetrachloride in rats

Anti-fibrogenic strategies and the regression of fibrosis

(2011) Tatiana Kisseleva et al.   BEST PRACTICE & RESEARCH IN CLINICAL GASTROENTEROLOGY

Mechanisms of hepatic fibrogenesis

(2011) Ursula E. Lee et al.   BEST PRACTICE & RESEARCH IN CLINICAL GASTROENTEROLOGY

TGF-β in progression of liver disease

(2011) Steven Dooley et al.   CELL AND TISSUE RESEARCH

Increases in p53 expression induce CTGF synthesis by mouse and human hepatocytes and result in liver fibrosis in mice

(2011) Takahiro Kodama et al.   JOURNAL OF CLINICAL INVESTIGATION

IL-13 Induces Connective Tissue Growth Factor in Rat Hepatic Stellate Cells via TGF- -Independent Smad Signaling

(2011) Y. Liu et al.   JOURNAL OF IMMUNOLOGY

A polymeric nanoparticle formulation of curcumin (NanoCurc™) ameliorates CCl4-induced hepatic injury and fibrosis through reduction of pro-inflammatory cytokines and stellate cell activation

(2011) Savita Bisht et al.   LABORATORY INVESTIGATION

Curcumin protects mice against concanavalin A-induced hepatitis by inhibiting intrahepatic intercellular adhesion molecule-1 (ICAM-1) and CXCL10 expression

(2011) Chuan-tao Tu et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Taking aim at the extracellular matrix: CCN proteins as emerging therapeutic targets

(2011) Joon-Il Jun et al.   NATURE REVIEWS DRUG DISCOVERY

Curcumin Inhibits Transforming Growth Factor-β Activity via Inhibition of Smad Signaling in HK-2 Cells

(2010) Ying Hu et al.   AMERICAN JOURNAL OF NEPHROLOGY

Connective tissue growth factor: a fibrogenic master switch in fibrotic liver diseases

(2010) Olav A. Gressner et al.   LIVER INTERNATIONAL

Perspectives on Chemopreventive and Therapeutic Potential of Curcumin Analogs in Medicinal Chemistry

(2010) S. Padhye et al.   MINI-REVIEWS IN MEDICINAL CHEMISTRY

Evolving challenges in hepatic fibrosis

(2010) Scott L. Friedman   Nature Reviews Gastroenterology & Hepatology

Pharmacological actions of curcumin in liver diseases or damage

(2009) Yadira Rivera-Espinoza et al.   LIVER INTERNATIONAL

Targeted disruption of Smad3 confers resistance to the development of dimethylnitrosamine-induced hepatic fibrosis in mice

(2009) Giovanni Latella et al.   LIVER INTERNATIONAL

Curcumin prevents and reverses cirrhosis induced by bile duct obstruction or CCl4in rats: role of TGF- modulation and oxidative stress

(2008) Karina Reyes-Gordillo et al.   FUNDAMENTAL & CLINICAL PHARMACOLOGY

Mechanisms of Hepatic Fibrogenesis

(2008) Scott L. Friedman   GASTROENTEROLOGY

Potential therapeutic effects of curcumin, the anti-inflammatory agent, against neurodegenerative, cardiovascular, pulmonary, metabolic, autoimmune and neoplastic diseases

(2008) Bharat B. Aggarwal et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Multi-targeted therapy by curcumin: how spicy is it?

(2008) Ajay Goel et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Curcumin inhibits connective tissue growth factor gene expression in activated hepatic stellate cellsin vitroby blocking NF-κB and ERK signalling

(2007) A Chen et al.   BRITISH JOURNAL OF PHARMACOLOGY