Occurrence of multipolar mitoses and association with Aurora-A/-B kinases and p53 mutations in aneuploid esophageal carcinoma cells

Elevated endogenous expression of the dominant negative basic helix-loop-helix protein ID1 correlates with significant centrosome abnormalities in human tumor cells

(2010) Carolin Manthey et al.   BMC CELL BIOLOGY

Stable knockdown of Aurora-A by vector-based RNA interference in human esophageal squamous cell carcinoma cell line inhibits tumor cell proliferation, invasion and enhances apoptosis

(2010) Xiaoxia Wang et al.   CANCER BIOLOGY & THERAPY

Aurora kinase A in Barrett’s carcinogenesis

(2010) Massimo Rugge et al.   HUMAN PATHOLOGY

The Molecular Basis of Carcinogenesis in Barrett’s Esophagus

(2010) Rhonda F. Souza   JOURNAL OF GASTROINTESTINAL SURGERY

Verification and Unmasking of Widely Used Human Esophageal Adenocarcinoma Cell Lines

(2010) Jurjen J. Boonstra et al.   JNCI-Journal of the National Cancer Institute

Aurora Kinase Inhibitors - Rising Stars in Cancer Therapeutics?

(2010) A. A. Dar et al.   MOLECULAR CANCER THERAPEUTICS

Deregulated Aurora-B induced tetraploidy promotes tumorigenesis

(2009) Hao G. Nguyen et al.   FASEB JOURNAL

Aurora A is differentially expressed and regulated in chromosomal and microsatellite instable sporadic colorectal cancers

(2009) Silke Lassmann et al.   MODERN PATHOLOGY

Boveri revisited: chromosomal instability, aneuploidy and tumorigenesis

(2009) Andrew J. Holland et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Structural Biology of the Tumor Suppressor p53

(2008) Andreas C. Joerger et al.   Annual Review of Biochemistry

Concomitant inhibition of Mdm2-p53 interaction and Aurora kinases activates the p53-dependent postmitotic checkpoints and synergistically induces p53-mediated mitochondrial apoptosis along with reduced endoreduplication in acute myelogenous leukemia

(2008) K. Kojima et al.   BLOOD

Prognostic Impact of Array-based Genomic Profiles in Esophageal Squamous Cell Cancer

(2008) Ana Carneiro et al.   BMC CANCER

Frequent overexpression of Aurora Kinase A in upper gastrointestinal adenocarcinomas correlates with potent antiapoptotic functions

(2008) Altaf A. Dar et al.   CANCER

Esophageal adenocarcinoma arising in Barrett esophagus

(2008) Hui Ying Zhang et al.   CANCER LETTERS

Genome-wide analysis of genetic alterations in Barrett's adenocarcinoma using single nucleotide polymorphism arrays

(2008) Thorsten Wiech et al.   LABORATORY INVESTIGATION

Nuclear epidermal growth factor receptor (EGFR) interacts with signal transducer and activator of transcription 5 (STAT5) in activating Aurora-A gene expression

(2008) Liang-Yi Hung et al.   NUCLEIC ACIDS RESEARCH