Article
Nutrition & Dietetics
Izzah Vasim, Chaudry N. Majeed, Mark D. DeBoer
Summary: Given the strain of the obesity epidemic on public health outcomes, new approaches to weight control are necessary. Intermittent fasting, with its beneficial metabolic effects, is an option to consider for individuals with unhealthy weight gain patterns. However, further research is needed for long-term outcomes and it should be avoided in specific health conditions.
Review
Clinical Neurology
Yuhan Karida Liu, Susan Ling, Leanna M. W. Lui, Felicia Ceban, Maj Vinberg, Lars Vedel Kessing, Roger C. Ho, Taeho Greg Rhee, Hartej Gill, Bing Cao, Rodrigo B. Mansur, Yena Lee, Joshua Rosenblat, Kayla M. Teopiz, Roger S. McIntyre
Summary: This study assessed the prevalence of type 2 diabetes, impaired fasting glucose, general obesity, and abdominal obesity in patients with bipolar disorder. The findings showed that patients with bipolar disorder had a higher prevalence of these conditions compared to the control group.
JOURNAL OF AFFECTIVE DISORDERS
(2022)
Review
Food Science & Technology
Xue Li, Binbin Nian, Ruizhi Li, Xinyu Cao, Yanjun Liu, Yuanfa Liu, Yong-Jiang Xu
Summary: This article conducted a meta-analysis to assess the effects of fasting on patients with metabolic syndrome (MS). The results showed that fasting significantly reduced body weight, BMI, body fat percentage, insulin level, and HOMA-IR in patients with MS, while having no effect on glucose, blood pressure, and lipids profile.
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
(2022)
Article
Nutrition & Dietetics
Josip Vrdoljak, Marko Kumric, Marino Vilovic, Dinko Martinovic, Veljko Rogosic, Josip A. Borovac, Tina Ticinovic Kurir, Josko Bozic
Summary: Metabolic syndrome is a group of metabolic abnormalities that have a high prevalence and economic burden worldwide. Fasting has emerged as a dietary method for controlling metabolic risk factors, although the effects on humans are still unclear. Preclinical studies have shown positive effects on gut microbiota, glucose and insulin metabolism, weight and visceral fat, and lipid metabolism. However, results from human studies are conflicting and more research is needed.
Article
Medicine, General & Internal
Myung Ji Nam, Hyunjin Kim, Yeon Joo Choi, Kyung-Hwan Cho, Seon Mee Kim, Yong-Kyun Roh, Kyungdo Han, Jin-Hyung Jung, Yong-Gyu Park, Joo-Hyun Park, Do-Hoon Kim
Summary: This study investigated the association between obesity indicators and the risk of impaired fasting glucose (IFG) in women, and found that obesity and abdominal obesity were consistently associated with increased odds of developing IFG after 8 years in both pre- and postmenopausal groups, with a stronger association in the premenopausal group. This highlights the need for weight management and lifestyle modification in premenopausal women.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Endocrinology & Metabolism
Domenico Corica, Giorgia Pepe, Tommaso Aversa, Monica Curro, Selenia Curatola, Alessandra Li Pomi, Angela Alibrandi, Riccardo Ientile, Malgorzata Wasniewska
Summary: The study found that postprandial asprosin levels significantly change in non-diabetic children and adolescents with obesity, and are associated with metabolic variables related to diabetes.
FRONTIERS IN ENDOCRINOLOGY
(2022)
Article
Biochemistry & Molecular Biology
Bing Liang, Le Shi, Dongyue Du, Hua Li, Ning Yi, Yue Xi, Jianjiao Cui, Ping Li, Hongbin Kang, Mami Noda, Xuejun Sun, Jiankang Liu, Shucun Qin, Jiangang Long
Summary: This study aims to investigate the effects of hydrogen-rich water on individuals with impaired fasting glucose (IFG) and explore the underlying mechanism involved. The results showed that hydrogen-rich water can slightly improve metabolic abnormalities and gut microbiota dysbiosis, providing a novel target and theoretical basis for the prevention and treatment of blood glucose regulation in patients with IFG.
Article
Cardiac & Cardiovascular Systems
Procolo Di Bonito, Giuliana Valerio, Maria R. Licenziati, Giuseppina Campana, Emanuele M. del Giudice, Anna Di Sessa, Anita Morandi, Claudio Maffeis, Claudio Chiesa, Lucia Pacifico, Marco G. Baroni, Melania Manco
Summary: The study revealed a significant association between uric acid levels and markers of prediabetes, insulin resistance, and insulin sensitivity in overweight/obese youth. Higher uric acid levels were correlated with elevated markers of impaired glucose metabolism, particularly post-challenge conditions.
NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES
(2021)
Article
Endocrinology & Metabolism
Yingting Zuo, Xinsheng Han, Xue Tian, Shuohua Chen, Shouling Wu, Anxin Wang
Summary: The study revealed that individuals without traditional ASCVD risk factors are at increased risk of developing CVD with higher levels of abnormal fasting plasma glucose, underlining the importance of prevention strategies targeting elevated FPG levels in addition to other traditional ASCVD risk factors.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
(2022)
Article
Biochemistry & Molecular Biology
Mauricio Castro-Sepulveda, Beatrice Morio, Mauro Tunon-Suarez, Sebastian Jannas-Vela, Francisco Diaz-Castro, Jennifer Rieusset, Hermann Zbinden-Foncea
Summary: This study aimed to investigate the mitochondrial dynamics response in human peripheral blood mononuclear cells during the metabolic transition from fasting to feeding. The results demonstrated that this transition reduces mitochondria-ER interactions, induces mitochondrial fission, and reduces mitochondrial cristae density in human PBMCs.
Article
Nutrition & Dietetics
Anna Kokkinopoulou, Ioannis Pagkalos, Nikolaos E. Rodopaios, Alexandra-Aikaterini Koulouri, Eleni Vasara, Sousana K. Papadopoulou, Petros Skepastianos, Maria Hassapidou, Anthony G. Kafatos
Summary: The study found that Christian Orthodox Church fasting has a positive effect on metabolic syndrome (MetS) in adults over 50 years old. Fasters had lower waist circumference, cholesterol levels, folic acid levels, and blood pressure compared to non-fasters. They also consumed less calories and fat.
Article
Public, Environmental & Occupational Health
Xin Zhang, Yankun Yue, Shaobo Liu, Xiangfeng Cong, Wenjuan Wang, Jianhong Li
Summary: This study investigates the relationship between BMI and the risk of impaired glucose tolerance (IGT) and impaired fasting glucose (IFG) in Chinese adults. The results show that obesity is an important risk factor for IGT and IFG in China, and the risk of IGT increases during the overweight stage.
Article
Endocrinology & Metabolism
Yue Liu, Huijun Zhuang, Na Han, Yuxing Yang, Qiao Zhang, Nianchun Peng, Ying Hu, Lixin Shi, Hong Li
Summary: This study investigated the incidence of metabolic syndrome (MS) in people over 40 years of age with normal blood glucose levels in Guiyang's urban areas and determined the effective glycemic cutoff value for predicting MS. The results showed a correlation between increased fasting plasma glucose (FPG) and the incidence of MS, even within the normal range. The study suggests that FPG testing can be used not only for diagnosing diabetes but also as a cost-effective screening method for predicting the development of MS in the general Chinese population.
DIABETES METABOLIC SYNDROME AND OBESITY
(2023)
Article
Public, Environmental & Occupational Health
Ibrahim Mahmoud, Nabil Sulaiman
Summary: This study estimates the prevalence of MetS and its associated risk factors in the UAE. The results show a high burden of MetS, particularly among Emirati women and Asian non-Arab men. Aggressive intervention strategies are recommended to prevent the development of cardiovascular diseases.
FRONTIERS IN PUBLIC HEALTH
(2022)
Article
Nutrition & Dietetics
Bo-Ying Zang, Li-Xia He, Ling Xue
Summary: Obesity and diabetes are significant health issues, and moderate weight loss is important for reducing the risk of metabolic diseases. Intermittent fasting (IF) is a popular weight loss strategy, but more research is needed, especially regarding its application in obese and type 2 diabetic patients.
Article
Surgery
Tassia Gomide Braga, Maria das Gracas Coelho de Souza, Priscila Alves Maranhao, Michel Menezes, Ludmilla Dellatorre-Teixeira, Eliete Bouskela, Carel W. Le Roux, Luiz Guilherme Kraemer-Aguiar
Article
Health Care Sciences & Services
Priscila A. Maranhao, Ana Margarida Pereira, Conceicao Calhau, Paula Ravasco, Federico Bozzetti, Alessandro Laviano, Liz Isenring, Elisa V. Bandera, Maureen B. Huhmann, Pedro Vieira-Marques, Ricardo J. Cruz-Correia
JOURNAL OF MEDICAL SYSTEMS
(2020)
Article
Surgery
Tassia Gomide Braga, Maria Das Gracas Coelho de Souza, Michel Menezes, Jose Firmino Nogueira Neto, Ludmilla Dellatorre-Teixeira, Eliete Bouskela, Carel W. le Roux, Luiz Guilherme Kraemer-Aguiar
Summary: The study found that bariatric surgery had a more significant impact on glucose metabolism, gut hormones, and inflammation, resulting in more extensive changes compared to medical treatment.
SURGERY FOR OBESITY AND RELATED DISEASES
(2021)
Article
Medicine, General & Internal
Alessandra Schiappacassa, Priscila A. Maranhao, Maria das Gracas Coelho de Souza, Diogo G. Panazzolo, Jose Firmino Nogueira Neto, Eliete Bouskela, Luiz Guilherme Kraemer-Aguiar
JOURNAL OF CLINICAL MEDICINE
(2020)
Article
Hematology
Maria das Gracas C. de Souza, Fatima Z. G. A. Cyrino, Fernando L. Sicuro, Eliete Bouskela
Summary: The protective effects of Ruscus extract on macromolecular permeability appear to be mediated solely through muscarinic receptors activation and do not require the release of EDRFs. In addition, NOS and COX inhibitors enhance the effect of Ruscus extract on microvascular permeability, suggesting a potential regulatory role for these enzymes in the mechanism of action of Ruscus extract.
CLINICAL HEMORHEOLOGY AND MICROCIRCULATION
(2021)
Article
Endocrinology & Metabolism
Elisabeth A. Machado, Paulo Farinatti, Fernando L. Sicuro, Flavio Rodrigues, Eliete Bouskela, Paulo F. Collett-Solberg
Summary: This study evaluated the association between cardiorespiratory fitness, abdominal obesity, blood pressure, endothelial function, and autonomic modulation in school-age adolescents exhibiting different levels of habitual physical activity and nutritional status. The results showed that poorer cardiorespiratory fitness corresponded to lower reactive hyperemia and vagal modulation, irrespective of the nutritional status. Additionally, endothelial and autonomic dysfunctions were more prevalent among adolescents combining poor cardiorespiratory fitness, reduced levels of daily physical activity, and overweight/obesity.
OBESITY RESEARCH & CLINICAL PRACTICE
(2021)
Article
Hematology
Camillo L. C. Junqueira, Esmeralci Ferreira, Adriana S. M. Junqueira, Fatima Z. G. A. Cyrino, Priscila A. Maranhao, Luiz Guilherme Kraemer-Aguiar, Daniel A. Bottino, Maria das Gracas C. de Souza, Eliete Bouskela
Summary: The study demonstrated that microvascular dysfunction present in the coronary microcirculation of patients with INOCA can also be detected noninvasively in their peripheral circulation, showing correlations with decreased red blood cell velocity, lower blood flow, and levels of biomarkers such as sVCAM-1, ET-1, and CRP.
CLINICAL HEMORHEOLOGY AND MICROCIRCULATION
(2021)
Article
Hematology
Karynne Grutter Lopes, Paulo Farinatti, Daniel Alexandre Bottino, Maria das Gracas Coelho de Souza, Priscila Alves Maranhao, Eliete Bouskela, Roberto Alves Lourenco, Ricardo Brandao de Oliveira
Summary: The study found that older adults classified as sarcopenic had lower muscle mass and strength, with no significant differences in microvascular function and morphology. However, inflammation status, particularly elevated levels of IL-6, appeared to play an important role in the development of sarcopenia.
CLINICAL HEMORHEOLOGY AND MICROCIRCULATION
(2022)
Article
Multidisciplinary Sciences
Fernando L. Sicuro, Luiz Flamarion B. Oliveira, Carla D. Hendges, Carlos Fonseca
Summary: The study in the Brazilian Pantanal confirmed that morphometric-proxies are reliable tools for inferring bite force, with a good correspondence between predicted and actual bite forces. Different capacities to crack food items reduce competition between collared and white-lipped peccaries. The results validate the biomechanical signal captured by morphometric proxies, confirming their utility for ecomorphological and evolutionary inferences.
Article
Surgery
Eline Coan Romagna, Diogo Menezes Ferrazani Mattos, Karynne Grutter Lopes, Luiz Guilherme Kraemer-Aguiar
Summary: This study investigated alcohol use, depressive symptoms, and health-related quality of life (HRQoL) in post-bariatric patients without medical follow-up, and compared these results between different levels of weight regain (RWR) and correlated with surgical outcomes. The findings showed that patients with higher weight regain had poorer health scores in physical functioning, physical role limitations, bodily pain, and vitality. The RWR was inversely correlated to physical/social functioning and vitality in the low RWR group, while positively associated with depressive symptoms and negatively associated with physical functioning and general health perception in the high RWR group.
Article
Nutrition & Dietetics
Karynne Grutter Lopes, Maria das Gracas Coelho de Souza, Eliete Bouskela, Luiz Guilherme Kraemer-Aguiar
Summary: Weight loss after bariatric surgery improves vascular function and metabolic/inflammatory profiles, reducing cardiovascular mortality. However, the effects of weight regain on vascular health are not well understood. This study compared post-bariatric patients with high weight regain to non-surgical controls and found that despite similar vascular function, post-bariatric patients still retained some metabolic/inflammatory benefits.
Article
Endocrinology & Metabolism
Karynne Grutter Lopes, Vicente Lopes da Silva Junior, Fernanda de Azevedo Marques Lopes, Eliete Bouskela, Maria das Gracas Coelho de Souza, Luiz Guilherme Kraemer-Aguiar
Summary: In this study, the biological behavior of ghrelin and glucagon-like peptide-1 (GLP-1) after a standard liquid meal was investigated, and it was found that the changes in ghrelin and GLP-1 were not influenced by body adiposity and glucose homeostasis.
ARCHIVES OF ENDOCRINOLOGY METABOLISM
(2023)
Article
Psychiatry
Karynne Grutter Lopes, Gabriel Pires dos Santos, Eline Coan Romagna, Diogo Menezes Ferrazani Mattos, Tassia Gomide Braga, Carolina Bastos Cunha, Priscila Alves Maranhao, Luiz Guilherme Kraemer-Aguiar
Summary: Long-term changes in appetite and taste were frequent among post-bariatric surgery patients. Different surgery types did not significantly affect sensory changes, with lower rate of weight regain associated with more taste and smell changes. Shorter time since surgery was linked to more frequent changes in appetite, taste, and smell.
EATING AND WEIGHT DISORDERS-STUDIES ON ANOREXIA BULIMIA AND OBESITY
(2022)
Article
Anatomy & Morphology
C. Tavares, F. L. Sicuro, R. M. Piergiorge, A. Vilasboa, K. A. Morelli, F. A. Monteiro, E. M. Costa-Paiva, J. Gusmao
Summary: This study conducted morphometric analysis to identify potential fishing stocks of Xiphopenaeus kroyeri along the Brazilian coast. The results revealed three main groups and indicated that the maritime limits practiced in Brazil align with the observed stock boundaries for Xiphopenaeus kroyeri s.s.
INTERNATIONAL JOURNAL OF MORPHOLOGY
(2021)