Article
Health Care Sciences & Services
Chun-Kai Chang, Jia-In Lee, Chu-Fen Chang, Yung-Chin Lee, Jhen-Hao Jhan, Hsun-Shuan Wang, Jung-Tsung Shen, Yao-Hsuan Tsao, Shu-Pin Huang, Jiun-Hung Geng
Summary: Betel nut chewing is associated with an increased risk of kidney stone disease, particularly among individuals who chew more than 30 quids per day.
JOURNAL OF PERSONALIZED MEDICINE
(2022)
Article
Construction & Building Technology
Zhijie Tang, Youwei Gan, Ting Yu, Chuangmin Li
Summary: This study investigated the effects of alkali-treated BNF on the water stability performance of asphalt mixtures using response surface methodology (RSM). The optimal solution showed improved low-temperature flexural strength and water stability, promoting the application of BNF in road construction. The prediction model demonstrated good reliability with test results within the 95% confidence interval.
CASE STUDIES IN CONSTRUCTION MATERIALS
(2022)
Article
Biochemical Research Methods
Adrian A. Franke, Xingnan Li, Thaddeus A. Herzog, Yvette C. Paulino, Grazyna Badowski, Lynne R. Wilkens, Jennifer F. Lai
Summary: The study analyzed saliva biomarker levels to verify the effectiveness of an intervention trial for quitting chewing betel nut. The results showed that saliva biomarker levels aligned with self-reported chewing status, suggesting that they can be used to objectively evaluate compliance and program effectiveness.
DRUG TESTING AND ANALYSIS
(2023)
Article
Nutrition & Dietetics
Yu-Tsung Chou, Zih-Jie Sun, Wei-Chen Shen, Yi-Ching Yang, Feng-Hwa Lu, Chih-Jen Chang, Chung-Yi Li, Jin-Shang Wu
Summary: Betel quid chewing is associated with liver fibrosis, and metabolic syndrome increases the risk of liver fibrosis.
FRONTIERS IN NUTRITION
(2022)
Article
Nutrition & Dietetics
Ya-Chin Huang, Jiun-Hung Geng, Pei-Yu Wu, Jiun-Chi Huang, Szu-Chia Chen, Jer-Ming Chang, Hung-Chun Chen
Summary: The habit of betel nut chewing in Taiwan is significantly associated with metabolic syndrome (MetS) and its components, and long-term betel nut chewing is related to the development of MetS.
Article
Plant Sciences
Huaiwen Zhang, Xue Zhao, Xianmei Cao, Latif Ullah Khan, Ruibai Zhao, Hongxing Wang, Xi Huang
Summary: This study demonstrates that APV1 is the causal agent of YLD in betel palm and is transmitted by Ferrisia virgata and Pseudococcus cryptus mealybugs. APV1 was detected in various parts of the mealybug vectors. However, it was not transmitted from female F. virgata to their offspring. This research fills important knowledge gaps in velarivirus transmission and has implications for YLD management.
Review
Dentistry, Oral Surgery & Medicine
Jun Yang, Zi-Yu Wang, Long Huang, Tao-Lin Yu, Shu-Qian Wan, Juan Song, Bing-Liang Zhang, Ming Hu
Summary: The study found a significant association between betel quid and areca nut chewing with poor prognosis in patients with oral cancer, indicating a higher risk of mortality among chewers compared to non-chewers.
Article
Multidisciplinary Sciences
Li Ying, Yunjia Yang, Jun Zhou, Hairong Huang, Guankui Du
Summary: The study found that betel nut chewing can decrease microbial diversity in the gut, leading to changes in specific bacterial families. While betel nut chewing may have positive effects on the gut microbiota by increasing beneficial microbes, it can also increase the abundance of disease-related microbes.
Review
Pharmacology & Pharmacy
Alan L. Myers
Summary: Areca nut is a widely self-administered psychoactive substance consumed by millions of people for its therapeutic and psychoactive effects. However, its use is associated with various oral and systemic side effects. The major pharmacological effects of areca nut are believed to be caused by its alkaloids, with arecoline being the most abundant and toxic alkaloid. The mechanisms of these alkaloids' elimination in humans are poorly documented. This review provides an in-depth analysis of the pharmacokinetics of areca alkaloids in biological systems, discussing their metabolism and toxicological relevance. Understanding the metabolism of areca alkaloids can help predict potential drug interactions.
DRUG METABOLISM REVIEWS
(2022)
Article
Biotechnology & Applied Microbiology
Yu-Hong Liu, Wei-Liang Chen
Summary: The study found a higher likelihood of diverticulosis in male betel nut chewers, particularly when combined with smoking and drinking. Obesity and elderly males showed higher adjusted odds ratios in the association between betel nut chewing and diverticulosis.
BIOMED RESEARCH INTERNATIONAL
(2021)
Review
Cell Biology
Liping Wang, Zhangui Tang
Summary: Oral submucous fibrosis (OSF) is a chronic, progressive, scarring, premalignant disease of the oral mucosa, with complex pathogenic factors including areca nut chewing, nutrition, genetics, and immune factors. Immune factors have recently become the focus of medical research on OSF, with attention on how they play a role in the disease's pathogenesis and treatment. OSF is characterized by significant changes in the immune microenvironment, prompting studies on the role of immune cells and substances in the disease.
JOURNAL OF LEUKOCYTE BIOLOGY
(2022)
Review
Endocrinology & Metabolism
Bashir Ahmad Laway, Mohammad Salem Baba
Summary: Sheehan syndrome caused by postpartum hemorrhage leads to pituitary hormone deficiency, resulting in various abnormalities including lipid and glucose abnormalities, increased body fat, insulin resistance, coagulation abnormalities, increased leptin concentration, low-grade inflammation, and endothelial dysfunction. Replacement with growth hormone in addition to standard hormone replacement improves the cardiometabolic profile of patients with Sheehan syndrome.
FRONTIERS IN ENDOCRINOLOGY
(2023)
Review
Oncology
Hui-Ching Chuang, Ming-Hsien Tsai, Yu-Tsai Lin, Ming-Huei Chou, Kun-Lin Yang, Chih-Yen Chien
Summary: The major predisposing factors of developing oral cancer include smoking, alcohol drinking, and betel quid chewing. Betel quid chewing could cause oral mucosa damage and lead to precancerous lesions and trismus. Betel quid-related oral cancer patients also have more systemic diseases than those without this habit. More attention should be paid to pretreatment evaluation, treatment strategy, and posttreatment follow-up among betel quid chewers.
TECHNOLOGY IN CANCER RESEARCH & TREATMENT
(2022)
Review
Endocrinology & Metabolism
Gaston L. Cluzel, Paul M. Ryan, Florence M. Herisson, Noel M. Caplice
Summary: This review describes and compares porcine models of metabolic syndrome, which is expected to be the greatest challenge to healthcare providers and policy makers in the future. Although no porcine model perfectly recapitulates the human metabolic syndrome, the Ossabaw miniature swine model is a highly translatable model.
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
(2022)
Review
Biochemistry & Molecular Biology
Pei-Feng Liu, Yung-Fu Chang
Summary: This review article highlights the traditional uses of Areca nut (AN) in herbal medicine and social activities, as well as its toxicological effects. The dual effects of AN, with both pharmacological and toxicological effects, are summarized. Perspectives and challenges in removing or modifying toxic compounds in AN extractions for future therapeutic applications are discussed.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Immunology
Kiran I. Masood, Shahid Pervez, Martin E. Rottenberg, Beena Umar, Zahra Hasan
JOURNAL OF MICROBIOLOGY IMMUNOLOGY AND INFECTION
(2016)
Meeting Abstract
Oncology
Z. A. Ahmed, S. Pervez, T. Moatter
JOURNAL OF THORACIC ONCOLOGY
(2016)
Article
Biochemistry & Molecular Biology
Tafheem Malik, Sheema Hasan, Shahid Pervez, Tasneem Fatima, Darakhshan Jabeen Haleem
NEUROCHEMICAL RESEARCH
(2016)
Review
Oncology
Zubair Ahmad, Romana Idrees, Saira Fatima, Huma Arshad, Nasir-ud Din, Aisha Memon, Khurram Minhas, Arsalan Ahmed, Syeda Samia Fatima, Muhammad Arif, Rashida Ahmed, Saroona Haroon, Shahid Pervez, Sheema Hassan, Naila Kayani
ASIAN PACIFIC JOURNAL OF CANCER PREVENTION
(2014)
Article
Oncology
Zeeshan Ansar Ahmed, Tariq Moatter, Areeba Siddiqui, Shahid Pervez
ASIAN PACIFIC JOURNAL OF CANCER PREVENTION
(2014)
Article
Nuclear Science & Technology
Kanwar Liaqat Ali, Akhlaque Ahmad Khan, Ahmad Mushtaq, Farhan Imtiaz, Maratab Ali Ziai, Amir Gulzar, Muhammad Farooq, Nazar Hussain, Nisar Ahmed, Shahid Pervez, Jamshed Hussain Zaidi
NUCLEAR ENGINEERING AND DESIGN
(2013)
Article
Oncology
Tariq Moatter, Muniba Aban, Waseem Iqbal, Shahid Pervez
PATHOLOGY & ONCOLOGY RESEARCH
(2015)
Article
Multidisciplinary Sciences
Shahida Tasneem, Muhammad Tahir Sarwar, Muhammad Rizwan Bashir, Hamid Hussain, Jawad Ahmed, Shahid Pervez
Article
Multidisciplinary Sciences
Shumaila M. Bilgrami, Sohail A. Qureshi, Shahid Pervez, Farhat Abbas
Article
Hematology
Nina Prokoph, Nicola A. Probst, Liam C. Lee, Jack M. Monahan, Jamie D. Matthews, Huan-Chang Liang, Klaas Bahnsen, Ivonne A. Montes-Mojarro, Elif Karaca-Atabay, Geeta G. Sharma, Vikas Malik, Hugo Larose, Sorcha D. Forde, Stephen P. Ducray, Cosimo Lobello, Qi Wang, Shi-Lu Luan, Sarka Pospisilova, Carlo Gambacorti-Passerini, G. A. Amos Burke, Shahid Pervez, Andishe Attarbaschi, Andrea Janikova, Helene Pacquement, Judith Landman-Parker, Anne Lambilliotte, Gudrun Schleiermacher, Wolfram Klapper, Ralf Jauch, Wilhelm Woessmann, Gilles Vassal, Lukas Kenner, Olaf Merkel, Luca Mologni, Roberto Chiarle, Laurence Brugieres, Birgit Geoerger, Isaia Barbieri, Suzanne D. Turner
Article
Multidisciplinary Sciences
Namrah Anwar, Shahid Pervez, Qurratulain Chundriger, Sohail Awan, Tariq Moatter, Tazeen Saeed Ali
Article
Infectious Diseases
Nuzhat Sultana, Walayat Shah, Waheed Iqbal, Shahid Pervez, Ikramullah Khan, Mohammad Hanif, Imran Khan
JOURNAL OF INFECTION IN DEVELOPING COUNTRIES
(2020)
Article
Medicine, General & Internal
Syed Muhammad Ishaque, Muhammad Sadiq Achackzai, Zia Ud Din, Shahid Pervez
Summary: This study aimed to determine the frequency of esophageal malignancy in Balochistan and evaluate its correlation with predisposing and dietary factors. The results showed that esophageal cancer was mainly associated with high-risk factors such as intake of spicy/salted food, hot beverages, drugs, quid, and tobacco smoking, as well as low intake of fruits and vegetables, lack of awareness, and low socioeconomic status.
PAKISTAN JOURNAL OF MEDICAL SCIENCES
(2022)
Proceedings Paper
Engineering, Aerospace
Mansoor Tariq, Zahida Najmi, Maria Firdous, Farah Saleem, Shahid Pervez, Farzeen Riaz
2019 SIXTH INTERNATIONAL CONFERENCE ON AEROSPACE SCIENCE AND ENGINEERING (ICASE)
(2019)
Article
Medicine, General & Internal
Nasir-Ud-Din, Arsalan Ahmed, Shahid Pervez, Rashida Ahmed, Naila Kayani
JCPSP-JOURNAL OF THE COLLEGE OF PHYSICIANS AND SURGEONS PAKISTAN
(2014)