Article
Cardiac & Cardiovascular Systems
Gianluca Di Bella, Giovanni Donato Aquaro, Jan Bogaert, Paolo Piaggi, Antonio Micari, Fausto Pizzino, Giovanni Camastra, Scipione Carerj, Mariapaola Campisi, Antonio Bracco, Maria Ludovica Carerj, Michele Emdin, Bijoy K. Khandheria, Alessandro Pingitore
Summary: Cardiovascular magnetic resonance imaging allows assessment of myocardial fibrosis and contractile function in patients with previous myocardial infarction. The presence of fibrotic myocardium showing contractile activity is associated with better patient survival in addition to other CMR imaging parameters.
JOURNAL OF CARDIOVASCULAR MAGNETIC RESONANCE
(2021)
Article
Multidisciplinary Sciences
Elizabeth K. K. Costello, Daniel B. B. DiGiulio, Anna Robaczewska, Laura Symul, Ronald J. J. Wong, Gary M. M. Shaw, David K. K. Stevenson, Susan P. P. Holmes, Douglas S. S. Kwon, David A. A. Relman
Summary: Childbirth leads to vaginal inflammation and a decrease in Lactobacillus dominance, which continues to affect women for up to one year postpartum. Only 49.4% of women were able to recover from this disturbance by the end of the first postpartum year, indicating a significant impact on women's health and future pregnancies.
NATURE COMMUNICATIONS
(2023)
Article
Neurosciences
Sharad B. Ghatge, Nirmal Surya, Dhaval Modi
Summary: This study retrospectively analyzed data of patients who underwent carotid stenting and found that some patients showed rapid neurological recovery from subacute to chronic ischemic stroke. These patients demonstrated significant improvement in both neurological and cognitive functions after the procedure.
Article
Radiology, Nuclear Medicine & Medical Imaging
Eyesha Hashim, Darren A. Yuen, Anish Kirpalani
Summary: Quantification of renal flow using IVIM-DWI has the potential to serve as a surrogate measure of IRI severity to estimate the degree of and recovery from DGF. Study results show that IVIM-DWI parameters are negatively correlated with the time to recovery related to MRI.
JOURNAL OF MAGNETIC RESONANCE IMAGING
(2021)
Article
Multidisciplinary Sciences
Chris Mays, Stephen McLoughlin, Tracy D. Frank, Christopher R. Fielding, Sam M. Slater, Vivi Vajda
Summary: The study shows that harmful algal and bacterial blooms are increasingly frequent in lakes and rivers due to deforestation, soil loss, and global warming. These blooms have consistently followed warming-related extinction events, inhibiting the recovery of freshwater ecosystems for millennia.
NATURE COMMUNICATIONS
(2021)
Article
Marine & Freshwater Biology
Michelle EH. Fournet, Erik Stabenau, Shyam Madhusudhana, Aaron N. Rice
Summary: This study assessed the impacts of human activities on ecological disturbance events in Florida Bay, finding that seagrass die offs have affected the composition and behavior of aquatic organisms. Analysis of acoustic data showed that the occurrence of certain species' calls and behaviors were significantly lower at the disturbed site compared to the undisturbed site. The results suggest that acoustic communities can serve as reliable indicators for evaluating ecosystem health and restoration success.
ESTUARINE COASTAL AND SHELF SCIENCE
(2022)
Article
Radiology, Nuclear Medicine & Medical Imaging
Mohsen Afarideh, Kai Jiang, Christopher M. Ferguson, John R. Woollard, James F. Glockner, Lilach O. Lerman
Summary: Magnetization transfer imaging is a novel noninvasive tool for detecting kidney fibrosis, and in this study, it was used to predict kidney recovery after PTRA in a swine model of renovascular disease. The results showed that STK-MTR is sensitive to hemodynamic changes after PTRA and can predict post-PTRA kidney perfusion, RBF, and fibrosis noninvasively. STK-MTR may be a valuable tool to predict renal hemodynamic and functional recovery, as well as residual kidney fibrosis after revascularization in RVD.
INVESTIGATIVE RADIOLOGY
(2021)
Article
Clinical Neurology
Yan-Ying Fan, Yu Li, Xiao-Ying Tian, Ying-Jing Wang, Jing Huo, Bao-Lu Guo, Ru Chen, Cai-Hong Yang, Yan Li, Hui-Feng Zhang, Bao-Long Niu, Ming-Sheng Zhang
Summary: This study found that acidic postconditioning can have neuroprotective effects during the acute phase of stroke. The effects of delayed chronic acidic postconditioning (DCAPC) during the subacute phase or other acute brain injuries were investigated. The results showed that DCAPC significantly promoted motor functional recovery and brain tissue repair, suggesting its therapeutic potential for stroke treatment.
TRANSLATIONAL STROKE RESEARCH
(2023)
Article
Surgery
Konstantinos Stavroulakis, Nikolaos Tsilimparis, Athanasios Saratzis, Barbara Rantner, Jan Stana, Anand Dayama, Mark G. Davies, Ryan Gouveia E. Melo
Summary: This study compared the risk of adverse renal events following endovascular revascularization (ER) or open surgery (OS) in patients with chronic limb-threatening ischemia (CLTI) and chronic kidney disease (CKD). The results showed that the incidence of postprocedural kidney injury or failure within 30 days was comparable between ER and OS. ER had significant benefits in terms of the primary outcome and renal failure, but not renal injury. Lower rates of major adverse cardiac and cerebrovascular events, target lesion revascularization, and readmissions were observed after ER.
JOURNAL OF ENDOVASCULAR THERAPY
(2023)
Article
Cardiac & Cardiovascular Systems
Shih-Sheng Chang, Chiung-Ray Lu, Ke-Wei Chen, Zhe-Wei Kuo, Shao-Hua Yu, Shih-Yi Lin, Hong-Mo Shi, Hei-Tung Yip, Chia-Hung Kao
Summary: This study investigated the prognostic differences between elderly patients with ST-elevation myocardial infarction (STEMI) and non-ST-elevation myocardial infarction (NSTEMI) by analyzing data from the Longitudinal Health Insurance Database in Taiwan. The results showed that there was no difference in cardiovascular and all-cause mortality between STEMI and NSTEMI in patients who received revascularization. However, in patients who did not receive revascularization, NSTEMI was associated with a higher risk of all-cause death. Moreover, there was no difference in major bleeding between STEMI and NSTEMI patients aged ≥65 years old.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2022)
Article
Physiology
Ciaran Deely, Jamie Tallent, Ross Bennett, Alex Woodhead, Stuart Goodall, Kevin Thomas, Glyn Howatson
Summary: The aim of this study was to profile the etiology and recovery time-course of neuromuscular function in professional academy soccer players. The researchers found that strenuous training led to a decrease in muscle strength and contractile function, but did not significantly affect mood, perceptual measures, or cognitive function.
FRONTIERS IN PHYSIOLOGY
(2022)
Article
Medicine, Research & Experimental
Alexandra Gratl, Dominik Pesta, Leonhard Gruber, Fiona Speichinger, Ben Raude, Safwan Omran, Andreas Greiner, Jan Paul Frese
Summary: This study found that revascularization procedures have significant effects on mitochondrial function and content in ischemic muscles, with no significant changes in non-ischemic muscles. This indicates that revascularization can promote mitochondrial recovery in affected muscle regions.
JOURNAL OF TRANSLATIONAL MEDICINE
(2021)
Article
Agriculture, Dairy & Animal Science
Shin-Ho Lee, Jae-Hyeon Cho, Chung-Hui Kim, Dongbin Lee
Summary: This study aims to collect objective data using walking analysis and digital thermal imaging to aid recovery from potential pain, inflammation, and lameness resulting from delayed rehabilitation after tibial plateau leveling osteotomy. The dog did not receive rehabilitation until 42 hours post-surgery, and gait analysis revealed insufficient weight support and an increase in relative body heat within the medial stifle joint. Cold treatment, transcutaneous electrical nerve stimulation, and treadmill exercise were applied to promote recovery. Despite its ability to enhance a dog's quality of life, veterinary rehabilitation is often neglected post-surgery.
Article
Cardiac & Cardiovascular Systems
H. Sophia Chen, Lenard M. Voortman, Conny van Munsteren, Lambertus J. Wisse, Bawer J. Tofig, Steen B. Kristiansen, Claire A. Glashan, Marco C. Deruiter, Katja Zeppenfeld, Monique R. M. Jongbloed
Summary: A novel method for quantifying nerve density and heterogeneity in large transmural biopsy sections has been developed. In the chronic phase after MI-R, alternating innervation patterns were identified within the same biopsy section. Persistent innervation heterogeneity, particularly in the border zone biopsy sections, may contribute to late arrhythmogenicity.
JACC-CLINICAL ELECTROPHYSIOLOGY
(2023)
Article
Cardiac & Cardiovascular Systems
Yong Hoon Kim, Ae-Young Her, Myung Ho Jeong, Byeong-Keuk Kim, Sung-Jin Hong, Seung-Jun Lee, Chul-Min Ahn, Jung-Sun Kim, Young-Guk Ko, Donghoon Choi, Myeong-Ki Hong, Yangsoo Jang
Summary: In the era of newer-generation DES, EI and DI strategies showed comparable major clinical outcomes in patients with NSTEMI and CKD during a 2-year follow-up period.
Editorial Material
Cardiac & Cardiovascular Systems
Martin Ugander
JACC-CARDIOVASCULAR IMAGING
(2020)
Article
Radiology, Nuclear Medicine & Medical Imaging
Alexander Fyrdahl, Joao G. Ramos, Maria J. Eriksson, Kenneth Caidahl, Martin Ugander, Andreas Sigfridsson
MAGNETIC RESONANCE IN MEDICINE
(2020)
Article
Cardiac & Cardiovascular Systems
Maren Maanja, Todd T. Schlegel, Rebecca Kozor, Magnus Lundin, Bjorn Wieslander, Timothy C. Wong, Erik B. Schelbert, Martin Ugander
JOURNAL OF ELECTROCARDIOLOGY
(2020)
Article
Cardiac & Cardiovascular Systems
Yanan Zong, Maren Maanja, Roza Chaireti, Todd T. Schlegel, Martin Ugander, Jovan P. Antovic
JOURNAL OF ELECTROCARDIOLOGY
(2020)
Article
Radiology, Nuclear Medicine & Medical Imaging
Magnus Lundin, Peder Sorensson, Eva Maret, Jonas Jenner, Goran Abdula, Jannike Nickander, Raquel Themudo, Kenneth Caidahl, Peter Kellman, Andreas Sigfridsson, Martin Ugander
Summary: Cardiovascular magnetic resonance can identify diffuse cardiac lesions not detected by late gadolinium enhancement. This study found that 8% of clinical cohort with heart disease had increased myocardial extracellular volume fraction (ECV), and 60% of these patients lacked focal lesions. Left ventricular size was independently associated with increased ECV, while systolic dysfunction was independently associated with late gadolinium enhancement.
JOURNAL OF THORACIC IMAGING
(2022)
Article
Radiology, Nuclear Medicine & Medical Imaging
Alexander Fyrdahl, Karen Holst, Kenneth Caidahl, Martin Ugander, Andreas Sigfridsson
Summary: The proposed novel double golden-angle profile ordering method successfully reduced the angular step while maintaining image uniformity. Simulations indicated a gradual degradation in image quality with decreasing angular steps and increasing physiological bins. Phantom images demonstrated improved image uniformity and robustness to off-resonance, with in vivo imaging confirming these findings.
MAGNETIC RESONANCE MATERIALS IN PHYSICS BIOLOGY AND MEDICINE
(2021)
Article
Cardiac & Cardiovascular Systems
Brett D. Atwater, Kasper Emerek, Zainab Samad, Edward Sze, Eric Black-Maier, Zak Loring, Martin Ugander, Lawrence Liao, Joseph Kisslo, Peter Sogaard, Daniel J. Friedman
AMERICAN JOURNAL OF CARDIOLOGY
(2020)
Article
Cardiac & Cardiovascular Systems
Ythan H. Goldberg, David Megyessi, Mischa Flam, Daniel M. Spevack, Martin G. Sundqvist, Martin Ugander
CARDIOVASCULAR ULTRASOUND
(2020)
Article
Cardiac & Cardiovascular Systems
Joao G. Ramos, Alexander Fyrdahl, Bjoern Wieslander, Simon Thalen, Gert Reiter, Ursula Reiter, Ning Jin, Eva Maret, Maria Eriksson, Kenneth Caidahl, Peder Soerensson, Andreas Sigfridsson, Martin Ugander
JACC-CARDIOVASCULAR IMAGING
(2020)
Article
Cardiac & Cardiovascular Systems
Martin G. Sundqvist, Anders Sahlen, Zee Pin Ding, Martin Ugander
CARDIOVASCULAR ULTRASOUND
(2020)
Article
Physiology
Katarina Steding-Ehrenborg, Erik Hedstrom, Marcus Carlsson, Elira Maksuti, Michael Broome, Martin Ugander, Martin Magnusson, J. Gustav Smith, Hakan Arheden
Summary: The hydraulic force generated by blood moving the atrioventricular plane is a novel mechanism of diastolic function, where the net hydraulic force aids in cardiac filling. Pathological remodeling may impact this mechanism negatively, exacerbating diastolic dysfunction in heart failure with preserved ejection fraction, while it may have a favorable effect in patients with dilated ventricles, such as heart failure with reduced ejection fraction.
JOURNAL OF APPLIED PHYSIOLOGY
(2021)
Article
Cardiac & Cardiovascular Systems
Thomas S. S. Hansen, Kristen J. J. Bubb, Gabriele G. G. Schiattarella, Martin Ugander, Timothy C. C. Tan, Gemma A. A. Figtree
Summary: This study evaluated the diagnostic performance of tricuspid annular plane systolic excursion (TAPSE), RV peak systolic myocardial velocity (s'), RV myocardial performance index (MPI), and RV fractional area change (FAC) in a mouse model of pulmonary hypertension. The results showed that these measures can be consistently measured in mice and are sensitive and specific indicators of pulmonary pressure and RV function.
JOURNAL OF THE AMERICAN HEART ASSOCIATION
(2022)
Review
Cardiac & Cardiovascular Systems
Thomas Lindow, Scott Quadrelli, Martin Ugander
Summary: Quantification of pulmonary edema and congestion is crucial for the diagnosis, risk stratification, and evaluation of new therapies in heart failure. Noninvasive imaging modalities, including chest x-ray, lung ultrasound, CT, nuclear medicine imaging methods, and MRI, have been validated and shown clinical utility in this setting. LUS is a useful bedside modality, while fully quantitative methods (CT, MRI, PET) are likely to provide more accurate evaluation of new heart failure therapies and can be used in conjunction with cardiac imaging. Further research is needed on pulmonary congestion during stress. Overall, noninvasive imaging of pulmonary congestion has both clinical and research utility, and improving methodologic accuracy, validation, and workflow can increase its broader clinical adoption.
JACC-CARDIOVASCULAR IMAGING
(2023)
Article
Cardiac & Cardiovascular Systems
Thomas Lindow, Aristomenis Manouras, Per Lindqvist, Daniel Manna, Bjorn Wieslander, Rebecca Kozor, Geoff Strange, David Playford, Martin Ugander
Summary: The estimation of pulmonary artery wedge pressure (PAWP) using echocardiography (ePAWP) has prognostic value beyond diastolic dysfunction grading.
EUROPEAN HEART JOURNAL-CARDIOVASCULAR IMAGING
(2023)
Article
Critical Care Medicine
Susanne Rysz, Johan Lundberg, Per Nordberg, Helen Eriksson, Bjorn Wieslander, Magnus Lundin, Alexander Fyrdahl, John Pernow, Martin Ugander, Therese Djarv, Malin Jonsson Fagerlund