PIK3CA mutation is a favorable prognostic factor in esophageal cancer: molecular profile by next-generation sequencing using surgically resected formalin-fixed, paraffin-embedded tissue

PIK3CA gene mutations in Northwest Chinese esophageal squamous cell carcinoma

(2017) Shi-Yuan Liu et al.   WORLD JOURNAL OF GASTROENTEROLOGY

Genomic Landscape of Esophageal Squamous Cell Carcinoma in a Japanese Population

(2016) Genta Sawada et al.   GASTROENTEROLOGY

Prospective Analysis of Oncogenic Driver Mutations and Environmental Factors: Japan Molecular Epidemiology for Lung Cancer Study

(2016) Tomoya Kawaguchi et al.   JOURNAL OF CLINICAL ONCOLOGY

The efficacy of uracil DNA glycosylase pretreatment in amplicon-based massively parallel sequencing with DNA extracted from archived formalin-fixed paraffin-embedded esophageal cancer tissues

(2015) Masakuni Serizawa et al.   Cancer Genetics

Epidermal Growth Factor Receptor Is a Prognosis Predictor in Patients With Esophageal Squamous Cell Carcinoma

(2014) Wencheng Zhang et al.   ANNALS OF THORACIC SURGERY

Establishment and characterization of esophageal squamous cell carcinoma patient-derived xenograft mouse models for preclinical drug discovery

(2014) Jingchuan Zhang et al.   LABORATORY INVESTIGATION

Identification of genomic alterations in oesophageal squamous cell cancer

(2014) Yongmei Song et al.   NATURE

Genetic landscape of esophageal squamous cell carcinoma

(2014) Yi-Bo Gao et al.   NATURE GENETICS

PIK3CA Gene Mutations and Overexpression: Implications for Prognostic Biomarker and Therapeutic Target in Chinese Esophageal Squamous Cell Carcinoma

(2014) Lin Wang et al.   PLoS One

PIK3CA hypomethylation plays a key role in activation of the PI3K/AKT pathway in esophageal cancer in Chinese patients

(2013) Wei-feng Wang et al.   ACTA PHARMACOLOGICA SINICA

Physiological expression of the PI3K-activating mutationPik3caH1047Rcombines withApcloss to promote development of invasive intestinal adenocarcinomas in mice

(2013) Lauren M. Hare et al.   BIOCHEMICAL JOURNAL

PIK3CA Mutation Is Associated with a Favorable Prognosis among Patients with Curatively Resected Esophageal Squamous Cell Carcinoma

(2013) H. Shigaki et al.   CLINICAL CANCER RESEARCH

Reducing Sequence Artifacts in Amplicon-Based Massively Parallel Sequencing of Formalin-Fixed Paraffin-Embedded DNA by Enzymatic Depletion of Uracil-Containing Templates

(2013) H. Do et al.   CLINICAL CHEMISTRY

Frequency, characterization, and prognostic analysis of PIK3CA gene mutations in Chinese esophageal squamous cell carcinoma

(2013) Jun Hou et al.   HUMAN PATHOLOGY

Epidemiology of Esophageal Cancer in Japan and China

(2013) Yingsong Lin et al.   JOURNAL OF EPIDEMIOLOGY

Clinical Validation of a Next-Generation Sequencing Screen for Mutational Hotspots in 46 Cancer-Related Genes

(2013) Rajesh R. Singh et al.   JOURNAL OF MOLECULAR DIAGNOSTICS

PIK3CA and APC mutations are synergistic in the development of intestinal cancers

(2013) D A Deming et al.   ONCOGENE

Prognostic Role of PIK3CA Mutation in Colorectal Cancer: Cohort Study and Literature Review

(2012) X. Liao et al.   CLINICAL CANCER RESEARCH

Clinicopathologic and biological analysis of PIK3CA mutation in ovarian clear cell carcinoma

(2012) Munmun Rahman et al.   HUMAN PATHOLOGY

Performance comparison of benchtop high-throughput sequencing platforms

(2012) Nicholas J Loman et al.   NATURE BIOTECHNOLOGY

Preoperative Chemoradiotherapy for Esophageal or Junctional Cancer

(2012) P. van Hagen et al.   NEW ENGLAND JOURNAL OF MEDICINE

High-Throughput Genotyping in Metastatic Esophageal Squamous Cell Carcinoma Identifies Phosphoinositide-3-Kinase and BRAF Mutations

(2012) Chi Hoon Maeng et al.   PLoS One

Long-term Outcome of 2920 Patients With Cancers of the Esophagus and Esophagogastric Junction

(2011) Ralf Gertler et al.   ANNALS OF SURGERY

A Randomized Trial Comparing Postoperative Adjuvant Chemotherapy with Cisplatin and 5-Fluorouracil Versus Preoperative Chemotherapy for Localized Advanced Squamous Cell Carcinoma of the Thoracic Esophagus (JCOG9907)

(2011) Nobutoshi Ando et al.   ANNALS OF SURGICAL ONCOLOGY

Effects of KRAS, BRAF, NRAS, and PIK3CA mutations on the efficacy of cetuximab plus chemotherapy in chemotherapy-refractory metastatic colorectal cancer: a retrospective consortium analysis

(2010) Wendy De Roock et al.   LANCET ONCOLOGY

Cycleave polymerase chain reaction method is practically applicable for V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog (KRAS)/V-raf murine sarcoma viral oncogene homolog B1 (BRAF) genotyping in colorectal cancer

(2010) Tomoya Yokota et al.   Translational Research

PIK3CA Mutations Predict Local Recurrences in Rectal Cancer Patients

(2009) Y. He et al.   CLINICAL CANCER RESEARCH

PIK3CA Mutation Associates with Improved Outcome in Breast Cancer

(2009) K. Kalinsky et al.   CLINICAL CANCER RESEARCH

PIK3CAMutation Is Associated With Poor Prognosis Among Patients With Curatively Resected Colon Cancer

(2009) Shuji Ogino et al.   JOURNAL OF CLINICAL ONCOLOGY

PIK3CA Mutation Status in Japanese Esophageal Squamous Cell Carcinoma

(2008) Ryota Mori et al.   JOURNAL OF SURGICAL RESEARCH

Class I PI3K in oncogenic cellular transformation

(2008) L Zhao et al.   ONCOGENE