Valproic acid sensitizes pancreatic cancer cells to natural killer cell-mediated lysis by upregulating MICA and MICB via the PI3K/Akt signaling pathway

Valproic Acid Upregulates NKG2D Ligand Expression through an ERK-dependent Mechanism and Potentially Enhances NK Cell-mediated Lysis of Myeloma

(2015) Xiaosong Wu et al.   NEOPLASIA

Chimeric NKG2D CAR-Expressing T Cell-Mediated Attack of Human Ovarian Cancer Is Enhanced by Histone Deacetylase Inhibition

(2013) De-Gang Song et al.   HUMAN GENE THERAPY

Akt1 Enhances CA916798 Expression through mTOR Pathway

(2013) Yu-Liang Wang et al.   PLoS One

Engineering lymph node homing of ex vivo-expanded human natural killer cells via trogocytosis of the chemokine receptor CCR7

(2012) S. S. Somanchi et al.   BLOOD

Melanoma cells become resistant to NK-cell-mediated killing when exposed to NK-cell numbers compatible with NK-cell infiltration in the tumor

(2012) Mirna Balsamo et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

HER2/HER3 Signaling Regulates NK Cell-Mediated Cytotoxicity via MHC Class I Chain-Related Molecule A and B Expression in Human Breast Cancer Cell Lines

(2012) R. Okita et al.   JOURNAL OF IMMUNOLOGY

3, 3′-Diindolylmethane Exhibits Antileukemic Activity In Vitro and In Vivo through a Akt-Dependent Process

(2012) Ning Gao et al.   PLoS One

Body mass index, abdominal fatness and pancreatic cancer risk: a systematic review and non-linear dose–response meta-analysis of prospective studies

(2011) D. Aune et al.   ANNALS OF ONCOLOGY

Global cancer statistics

(2011) Ahmedin Jemal et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Human Ovarian Tumor Cells Escape γδ T Cell Recognition Partly by Down Regulating Surface Expression of MICA and Limiting Cell Cycle Related Molecules

(2011) Jingwei Lu et al.   PLoS One

Induction of a CD8+ T-cell response to the MAGE cancer testis antigen by combined treatment with azacitidine and sodium valproate in patients with acute myeloid leukemia and myelodysplasia

(2010) O. Goodyear et al.   BLOOD

Radiosensitization of Epidermal Growth Factor Receptor/HER2-Positive Pancreatic Cancer Is Mediated by Inhibition of Akt Independent of Ras Mutational Status

(2010) R. J. Kimple et al.   CLINICAL CANCER RESEARCH

Clinical significance of the immunostimulatory MHC class I chain-related molecule A and NKG2D receptor on NK cells in pancreatic cancer

(2010) Xiaohui Duan et al.   MEDICAL ONCOLOGY

p21 Downregulation is an important component of PAX3/FKHR oncogenicity and its reactivation by HDAC inhibitors enhances combination treatment

(2010) R M Hecker et al.   ONCOGENE

Hydroxyurea upregulates NKG2D ligand expression in myeloid leukemia cells synergistically with valproic acid and potentially enhances susceptibility of leukemic cells to natural killer cell-mediated cytolysis

(2009) Xuzhang Lu et al.   CANCER SCIENCE

HDAC2 mediates therapeutic resistance of pancreatic cancer cells via the BH3-only protein NOXA

(2009) P Fritsche et al.   GUT

Effective in vivo induction of NKG2D ligands in acute myeloid leukaemias by all-trans-retinoic acid or sodium valproate

(2009) A Poggi et al.   LEUKEMIA

ATM-ATR-dependent up-regulation of DNAM-1 and NKG2D ligands on multiple myeloma cells by therapeutic agents results in enhanced NK-cell susceptibility and is associated with a senescent phenotype

(2008) A. Soriani et al.   BLOOD

Hypoxia Increases Tumor Cell Shedding of MHC Class I Chain-Related Molecule: Role of Nitric Oxide

(2008) D. R. Siemens et al.   CANCER RESEARCH

Decreased Dicer expression elicits DNA damage and up-regulation of MICA and MICB

(2008) Kai-Fu Tang et al.   JOURNAL OF CELL BIOLOGY