BIMELis a key effector molecule in oxidative stress-mediated apoptosis in acute myeloid leukemia cells when combined with arsenic trioxide and buthionine sulfoximine

Combination Therapy with Arsenic Trioxide for Hematological Malignancies

(2012) Shinichiro Takahashi   Anti-Cancer Agents in Medicinal Chemistry

Carbonyl Reductase 1 Offers a Novel Therapeutic Target to Enhance Leukemia Treatment by Arsenic Trioxide

(2012) Miran Jang et al.   CANCER RESEARCH

Ethacrynic Acid and a Derivative Enhance Apoptosis in Arsenic Trioxide-Treated Myeloid Leukemia and Lymphoma Cells: The Role of Glutathione S-Transferase P1-1

(2012) R. Wang et al.   CLINICAL CANCER RESEARCH

Therapeutic targets in the ASK1-dependent stress signaling pathways

(2012) Ryoichi HAYAKAWA et al.   PROCEEDINGS OF THE JAPAN ACADEMY SERIES B-PHYSICAL AND BIOLOGICAL SCIENCES

Mechanisms and clinical significance of BIM phosphorylation in chronic lymphocytic leukemia

(2011) A. Paterson et al.   BLOOD

Distribution of Bim determines Mcl-1 dependence or codependence with Bcl-xL/Bcl-2 in Mcl-1-expressing myeloma cells

(2011) A. A. Morales et al.   BLOOD

Apoptosis and oncogenesis: give and take in the BCL-2 family

(2011) Fabien Llambi et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Identification of 3H-Naphtho[1,2,3-de]quinoline-2,7-diones as Inhibitors of Apoptosis Signal-Regulating Kinase 1 (ASK1)

(2011) Galyna P. Volynets et al.   JOURNAL OF MEDICINAL CHEMISTRY

BH3-only proteins: Orchestrators of apoptosis

(2010) Aisha Shamas-Din et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Role of Bim in diallyl trisulfide-induced cytotoxicity in human cancer cells

(2010) Byeong-Chel Lee et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Apoptosis and autophagy: BIM as a mediator of tumour cell death in response to oncogene-targeted therapeutics

(2009) Annette S. Gillings et al.   FEBS Journal

Stepwise Activation of BAX and BAK by tBID, BIM, and PUMA Initiates Mitochondrial Apoptosis

(2009) Hyungjin Kim et al.   MOLECULAR CELL

Redox control of cell fate by MAP kinase: physiological roles of ASK1-MAP kinase pathway in stress signaling

(2008) Atsushi Matsuzawa et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Acute promyelocytic leukemia: from highly fatal to highly curable

(2008) Z.-Y. Wang et al.   BLOOD

Multisite Phosphorylation Regulates Bim Stability and Apoptotic Activity

(2008) Anette Hübner et al.   MOLECULAR CELL

BAX activation is initiated at a novel interaction site

(2008) Evripidis Gavathiotis et al.   NATURE