Optimisation of an immunohistochemistry method for the determination of androgen receptor expression levels in circulating tumour cells

Discovery of AZD3514, a small-molecule androgen receptor downregulator for treatment of advanced prostate cancer

(2013) Robert H. Bradbury et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Method validation of circulating tumour cell enumeration at low cell counts

(2013) Jeffrey Cummings et al.   BMC CANCER

AZD3514: A Small Molecule That Modulates Androgen Receptor Signaling and Function In Vitro and In Vivo

(2013) S. A. Loddick et al.   MOLECULAR CANCER THERAPEUTICS

Small-molecule androgen receptor downregulators as an approach to treatment of advanced prostate cancer

(2011) Robert H. Bradbury et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Detection of circulating tumour cells with a hybrid (epithelial/mesenchymal) phenotype in patients with metastatic non-small cell lung cancer

(2011) A Lecharpentier et al.   BRITISH JOURNAL OF CANCER

A pilot study to explore circulating tumour cells in pancreatic cancer as a novel biomarker

(2011) L Khoja et al.   BRITISH JOURNAL OF CANCER

Application of the β-expectation tolerance interval to method validation of the M30 and M65 ELISA cell death biomarker assays

(2011) Jeffrey Cummings et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

PC3 is a cell line characteristic of prostatic small cell carcinoma

(2011) Sheng Tai et al.   PROSTATE

The Use of Immunohistochemistry for Biomarker Assessment—Can It Compete with Other Technologies?

(2011) Robert W. Dunstan et al.   TOXICOLOGIC PATHOLOGY

Cytopathologic Detection of Circulating Tumor Cells Using the Isolation by Size of Epithelial Tumor Cell Method

(2010) Véronique J. Hofman et al.   AMERICAN JOURNAL OF CLINICAL PATHOLOGY

Fit-for-purpose biomarker method validation for application in clinical trials of anticancer drugs

(2010) J Cummings et al.   BRITISH JOURNAL OF CANCER

External quality assurance of circulating tumor cell enumeration using the CellSearch® system: A feasibility study

(2010) Jaco Kraan et al.   CYTOMETRY PART B-CLINICAL CYTOMETRY

Fit-for-purpose biomarker method validation in anticancer drug development

(2010) Jeffrey Cummings et al.   DRUG DISCOVERY TODAY

Partners in crime: deregulation of AR activity and androgen synthesis in prostate cancer

(2010) Karen E. Knudsen et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Statistical Considerations for Assessment of Bioanalytical Incurred Sample Reproducibility

(2009) David Hoffman   AAPS Journal

Workshop Report and Follow-Up—AAPS Workshop on Current Topics in GLP Bioanalysis: Assay Reproducibility for Incurred Samples—Implications of Crystal City Recommendations

(2009) Douglas M. Fast et al.   AAPS Journal

Do we see what we think we see? The complexities of morphological assessment

(2009) Peter W Hamilton et al.   JOURNAL OF PATHOLOGY

Circulating tumour cells as prognostic markers in progressive, castration-resistant prostate cancer: a reanalysis of IMMC38 trial data

(2009) Howard I Scher et al.   LANCET ONCOLOGY

Significance of Circulating Tumor Cells Detected by the CellSearch System in Patients with Metastatic Breast Colorectal and Prostate Cancer

(2009) M. Craig Miller et al.   Journal of Oncology

Circulating Tumor Cells Predict Survival Benefit from Treatment in Metastatic Castration-Resistant Prostate Cancer

(2008) J. S. de Bono et al.   CLINICAL CANCER RESEARCH

Do we truly see what we think we see? The role of cognitive bias in pathological interpretation

(2008) TM Fandel et al.   JOURNAL OF PATHOLOGY

Twisted epithelial–mesenchymal transition blocks senescence

(2008) Robert A. Weinberg   NATURE CELL BIOLOGY

Biomarker method validation in anticancer drug development

(2007) J Cummings et al.   BRITISH JOURNAL OF PHARMACOLOGY