In vitro and in vivo effects of geranylgeranyltransferase I inhibitor P61A6 on non-small cell lung cancer cells

Targeting GGTase-I Activates RHOA, Increases Macrophage Reverse Cholesterol Transport, and Reduces Atherosclerosis in Mice

(2013) Omar M. Khan et al.   CIRCULATION

Functional Interaction of Tumor Suppressor DLC1 and Caveolin-1 in Cancer Cells

(2012) X. Du et al.   CANCER RESEARCH

Geranylgeranyltransferase type I (GGTase-I) deficiency hyperactivates macrophages and induces erosive arthritis in mice

(2011) Omar M. Khan et al.   JOURNAL OF CLINICAL INVESTIGATION

Identification and Characterization of Mechanism of Action of P61-E7, a Novel Phosphine Catalysis-Based Inhibitor of Geranylgeranyltransferase-I

(2011) Lai N. Chan et al.   PLoS One

In vivo antitumor effect of a novel inhibitor of protein geranylgeranyltransferase-I

(2009) J. Lu et al.   MOLECULAR CANCER THERAPEUTICS

Inhibition of Tumor Growth and Metastasis by Non–Small Cell Lung Cancer Cells Transfected With Cyclin D1–Targeted siRNA

(2009) Hu Huang et al.   OLIGONUCLEOTIDES

p120Ras-GAP binds the DLC1 Rho-GAP tumor suppressor protein and inhibits its RhoA GTPase and growth-suppressing activities

(2009) X-Y Yang et al.   ONCOGENE

The anandamide analog, Met-F-AEA, controls human breast cancer cell migration via the RHOA/RHO kinase signaling pathway

(2008) C. Laezza et al.   ENDOCRINE-RELATED CANCER

Rho GTPases in cancer cell biology

(2008) Francisco M. Vega et al.   FEBS LETTERS

DLC1 is a chromosome 8p tumor suppressor whose loss promotes hepatocellular carcinoma

(2008) W. Xue et al.   GENES & DEVELOPMENT

DLC1: a significant GAP in the cancer genome

(2008) A. Lahoz et al.   GENES & DEVELOPMENT

Inhibitors of Protein Geranylgeranyltransferase I and Rab Geranylgeranyltransferase Identified from a Library of Allenoate-derived Compounds

(2008) Masaru Watanabe et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

DLC-1 suppresses non-small cell lung cancer growth and invasion by RhoGAP-dependent and independent mechanisms

(2007) Kevin D. Healy et al.   MOLECULAR CARCINOGENESIS