Activation of AKT by hypoxia: a potential target for hypoxic tumors of the head and neck

Biomarkers of Response to Akt Inhibitor MK-2206 in Breast Cancer

(2012) T. Sangai et al.   CLINICAL CANCER RESEARCH

Epidermal Growth Factor Receptor Protein Detection in Head and Neck Cancer Patients: A Many-Faceted Picture

(2012) Juliette Thariat et al.   CLINICAL CANCER RESEARCH

Hypoxia-induced SM22α in A549 cells activates the IGF1R/PI3K/Akt pathway, conferring cellular resistance against chemo- and radiation therapy

(2012) Tae Rim Kim et al.   FEBS LETTERS

Accelerated Radiotherapy With Carbogen and Nicotinamide for Laryngeal Cancer: Results of a Phase III Randomized Trial

(2012) Geert O. Janssens et al.   JOURNAL OF CLINICAL ONCOLOGY

SET protein accumulates in HNSCC and contributes to cell survival: Antioxidant defense, Akt phosphorylation and AVOs acidification

(2012) Andréia M. Leopoldino et al.   ORAL ONCOLOGY

Disruption of the AKT pathway inhibits metastasis in an orthotopic model of head and neck squamous cell carcinoma

(2011) Joseph A. Knowles et al.   LARYNGOSCOPE

Inhibition of STAT-3 results in greater cetuximab sensitivity in head and neck squamous cell carcinoma

(2011) James A. Bonner et al.   RADIOTHERAPY AND ONCOLOGY

HIF-2 -mediated activation of the epidermal growth factor receptor potentiates head and neck cancer cell migration in response to hypoxia

(2010) X. Wang et al.   CARCINOGENESIS

Significance of Interleukin-6 Signaling in the Resistance of Pharyngeal Cancer to Irradiation and the Epidermal Growth Factor Receptor Inhibitor

(2010) Chih-Cheng Chen et al.   INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS

Understanding resistance to EGFR inhibitors—impact on future treatment strategies

(2010) Deric L. Wheeler et al.   Nature Reviews Clinical Oncology

Combination Treatment with MEK and AKT Inhibitors Is More Effective than Each Drug Alone in Human Non-Small Cell Lung Cancer In Vitro and In Vivo

(2010) Jieru Meng et al.   PLoS One

Targeting EGFR resistance networks in head and neck cancer

(2009) Vladimir Ratushny et al.   CELLULAR SIGNALLING

EGFR, HER2, and HER3 Expression in Laryngeal Primary Tumors and Corresponding Metastases

(2008) Qichun Wei et al.   ANNALS OF SURGICAL ONCOLOGY

Epidermal growth factor receptor status and persistent activation of Akt and p44/42 MAPK pathways correlate with the effect of cetuximab in head and neck and colon cancer cell lines

(2008) Takashi Yamatodani et al.   JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY

Activation of the PI3-K/AKT pathway and implications for radioresistance mechanisms in head and neck cancer

(2008) Johan Bussink et al.   LANCET ONCOLOGY

Molecular aspects of tumour hypoxia

(2008) Saskia E. Rademakers et al.   Molecular Oncology

Mechanisms of acquired resistance to cetuximab: role of HER (ErbB) family members

(2008) D L Wheeler et al.   ONCOGENE

Signaling networks assembled by oncogenic EGFR and c-Met

(2008) A. Guo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

High rate of severe radiation dermatitis during radiation therapy with concurrent cetuximab in head and neck cancer: Results of a survey in EORTC institutes

(2008) Christian Giro et al.   RADIOTHERAPY AND ONCOLOGY