A cyclopalladated complex interacts with mitochondrial membrane thiol-groups and induces the apoptotic intrinsic pathway in murine and cisplatin-resistant human tumor cells

Gene Therapy against Murine Melanoma B16F10-Nex2 Using IL-13Rα2-Fc Chimera and Interleukin 12 in Association with a Cyclopalladated Drug

(2014) Flavia Hebeler-Barbosa et al.   Translational Oncology

Advances in Platinum Chemotherapeutics

(2010) Benjamin W. Harper et al.   CHEMISTRY-A EUROPEAN JOURNAL

Synthesis of chiral β-aminoalcohol palladium complexes exhibiting cytotoxic properties

(2010) Fabien Accadbled et al.   DALTON TRANSACTIONS

Antimycobacterial and antitumor activities of Palladium(II) complexes containing isonicotinamide (isn): X-ray structure of trans-[Pd(N3)2(isn)2]

(2010) Rodrigo A. de Souza et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Evaluation of in vitro cytotoxicity and hepatotoxicity of platinum(II) and palladium(II) oxalato complexes with adenine derivatives as carrier ligands

(2010) Radim Vrzal et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Targeting mitochondria for cancer therapy

(2010) Simone Fulda et al.   NATURE REVIEWS DRUG DISCOVERY

Calcium and cell death signaling in neurodegeneration and aging

(2009) Soraya Smaili et al.   ANAIS DA ACADEMIA BRASILEIRA DE CIENCIAS

Systemic Therapy for Cutaneous Melanoma

(2009) Jonathan Treisman et al.   CLINICS IN PLASTIC SURGERY

Mechanisms of Tumor Cell Necrosis

(2009) Sergey Proskuryakov et al.   CURRENT PHARMACEUTICAL DESIGN

The mechanism of action of platinum anticancer agents—what do we really know about it?

(2009) Dan Gibson   DALTON TRANSACTIONS

Mitochondrial gateways to cancer

(2009) Lorenzo Galluzzi et al.   MOLECULAR ASPECTS OF MEDICINE

Palladacycles catalyse the oxidation of critical thiols of the mitochondrial membrane proteins and lead to mitochondrial permeabilization and cytochromecrelease associated with apoptosis

(2008) Débora P. Santana et al.   BIOCHEMICAL JOURNAL

Necroptosis: A Specialized Pathway of Programmed Necrosis

(2008) Lorenzo Galluzzi et al.   CELL

Pre-clinical antitumour evaluation of Biphosphinic Palladacycle Complex in human leukaemia cells

(2008) Carlos R. Oliveira et al.   CHEMICO-BIOLOGICAL INTERACTIONS

The Role of Cellular Accumulation in Determining Sensitivity to Platinum-Based Chemotherapy

(2007) Matthew D. Hall et al.   Annual Review of Pharmacology and Toxicology