Protein dynamics and conformational selection in bidirectional signal transduction

Molecular dynamics simulations and drug discovery

(2011) Jacob D Durrant et al.   BMC BIOLOGY

How do dynamic cellular signals travel long distances?

(2011) Ruth Nussinov   Molecular BioSystems

In Silico Elucidation of the Recognition Dynamics of Ubiquitin

(2011) Dong Long et al.   PLoS Computational Biology

Protein kinases: evolution of dynamic regulatory proteins

(2010) Susan S. Taylor et al.   TRENDS IN BIOCHEMICAL SCIENCES

Amplification of signaling via cellular allosteric relay and protein disorder

(2009) B. Ma et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Conformational selection and induced fit mechanism underlie specificity in noncovalent interactions with ubiquitin

(2009) T. Wlodarski et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Origin of Allosteric Functional Modulation: Multiple Pre-existing Pathways

(2009) Antonio del Sol et al.   STRUCTURE

Structural Plasticity of Eph Receptor A4 Facilitates Cross-Class Ephrin Signaling

(2009) Thomas A. Bowden et al.   STRUCTURE

Recognition Dynamics Up to Microseconds Revealed from an RDC-Derived Ubiquitin Ensemble in Solution

(2008) O. F. Lange et al.   SCIENCE

Eph, a Protein Family Coming of Age: More Confusion, Insight, or Complexity?

(2008) M. Lackmann et al.   Science Signaling