Article
Microbiology
Ya-Fang Chiu, Yi-Wen Huang, Chi-Yuan Chen, Yu-Chia Chen, Yu-Nong Gong, Rei-Lin Kuo, Chung-Guei Huang, Shin-Ru Shih
Summary: This study utilized an MS2-MCP live-cell imaging system to visualize the replication of Influenza A virus (IAV) and found that the replication of IAV vRNA mainly occurs in apoptotic cells, highlighting the significant role of apoptosis in IAV vRNA replication.
FRONTIERS IN MICROBIOLOGY
(2022)
Article
Biology
Andrzej Zielezinski, Jakub Barylski, Wojciech M. Karlowski
Summary: Phirbo is a tool based on the extension of BLAST that improves the quality of phage host prediction, increasing precision and recall rates. It has high discriminatory power in identifying virus-host relationships compared to other tools.
Article
Biochemistry & Molecular Biology
Zilong Li, Jonas Meisner, Anders Albrechtsen
Summary: Principal component analysis (PCA) is widely used for dimensionality reduction and uncovering latent structure in statistics, machine learning, and genomics. To address the challenges of ever-growing data, this paper proposes a novel algorithm called PCAone, which achieves fast and memory-efficient PCA and outperforms existing methods in comprehensive evaluations using multiple large-scale real-world datasets.
Article
Computer Science, Artificial Intelligence
Paul Augustine Ejegwa, Idoko Charles Onyeke, Nasreen Kausar, Parameshwari Kattel
Summary: Computation of correlation coefficient among attributes of ordinary database is important especially in the classification and analysis of data. To achieve a dependable correlation, the construct of partial correlation coefficient based on IFD has been considered. In this study, a novel approach of finding PCCIFSs by incorporating the three parameters of IFD based on a modified CCIFSs approach is proposed, compared to the existing approach.
INTERNATIONAL JOURNAL OF INTELLIGENT SYSTEMS
(2023)
Article
Virology
Sho Miyamoto, Yukiko Muramoto, Keiko Shindo, Yoko Fujita-Fujiharu, Takeshi Morikawa, Ryoma Tamura, Jamie L. Gilmore, Masahiro Nakano, Takeshi Noda
Summary: This study provides evidence that the packaging signals between HA vRNA and PB2 vRNA are important for the selective genome packaging of the influenza A virus. Understanding the packaging mechanism of the influenza virus genome is crucial for developing strategies to combat influenza.
JOURNAL OF VIROLOGY
(2022)
Article
Engineering, Environmental
Xiawan Zheng, Keyue Zhao, Xiaoqing Xu, Yu Deng, Kathy Leung, Joseph T. Wu, Gabriel M. Leung, Malik Peiris, Leo L. M. Poon, Tong Zhang
Summary: Wastewater surveillance is an effective tool for controlling infectious diseases, providing cost-effective and real-time monitoring results. In this study, we developed preanalytical protocols for influenza virus surveillance in wastewater and conducted large-scale monitoring in Hong Kong. The concentration of influenza viruses in wastewater was associated with clinical detection rates and illness rates in the community, and increased significantly after the mask mandate was cancelled.
Article
Biology
Jennifer E. Jones, Valerie Le Sage, Gabriella H. Padovani, Michael Calderon, Erik S. Wright, Seema S. Lakdawala
Summary: Influenza viruses evolve rapidly during infection through mutations or reassortment, potentially leading to strains with increased resistance or infectivity. Understanding how genome segments interact during reassortment can help predict future events and emergence of new pandemic strains. Research in this area could provide valuable insights for risk assessment and pandemic preparedness.
Article
Multidisciplinary Sciences
Mariana Leguia, Alejandra Garcia-Glaessner, Breno Munoz-Saavedra, Diana Juarez, Patricia Barrera, Carlos Calvo-Mac, Javier Jara, Walter Silva, Karl Ploog, Lady Amaro, Paulo Colchao-Claux, Christine K. Johnson, Marcela M. Uhart, Martha I. Nelson, Jesus Lescano
Summary: Highly pathogenic avian influenza A/H5N1 viruses have invaded the Americas and pose a threat to wildlife, poultry, and humans. The HPAI/H5N1 viruses in Peru have genetic reassortment between Eurasian and American lineages, emphasizing the need for surveillance and control measures.
NATURE COMMUNICATIONS
(2023)
Article
Pharmacology & Pharmacy
Shengrui Mu, Xiaohui Zou, Yeming Wang, Xiaoyan Deng, Dan Cui, Shuai Liu, Bo Cao
Summary: Our study investigated the virological evolution and resistance mutation against oseltamivir in patients with influenza who underwent combination therapy of favipiravir and oseltamivir. We found that the combination therapy had little effect on virus nucleotide diversity and did not prevent the increase of oseltamivir-resistant variants. The dominant variant type observed was the G→A transition, and mutations conferring reduction in oseltamivir sensitivity were detected, with H275Y being the only mutation present.
ANTIVIRAL RESEARCH
(2023)
Article
Biochemistry & Molecular Biology
Jianmin Xie, Yuerong Chen, Guanjing Cai, Runlin Cai, Zhong Hu, Hui Wang
Summary: tvBOT is a user-friendly and efficient web application for visualizing, modifying, and annotating phylogenetic trees. It excels in data preparation by eliminating redundant style and syntax data. With a data-driven engine, tvBOT allows annotations with practical data organized in uniform formats, making it easy to add specific layers of annotation dataset. It supports real-time and diversified style adjustments, and can be used on mobile devices. Furthermore, tvBOT offers multiple formats for tree annotations by combining 26 annotation dataset types. It also allows exporting the final drawing state and related data in JSON format for sharing, editing, or using as a style template. tvBOT is available for free at: https://www.chiplot.online/tvbot.html.
NUCLEIC ACIDS RESEARCH
(2023)
Article
Virology
Gregory Queromes, Emilie Frobert, Elena Burtseva, Anca Draganescu, Paravaiz A. Koul, Andrey Komissarov, V. Alberto Laguna-Torres, Jason Leblanc, F-Xavier Lopez-Labrador, Snezana Medic, Alla Mironenko, Nancy A. Otieno, Guillermo M. Ruiz-Palacios, M. Tanriover, Laurence Josset, Bruno Lina
Summary: The Global Influenza Hospital Surveillance Network (GIHSN) confirms its ability to provide valuable information on influenza infection dynamics in hospital settings through standardized data collection and analysis.
JOURNAL OF CLINICAL VIROLOGY
(2022)
Article
Infectious Diseases
Hayato Harima, Kosuke Okuya, Masahiro Kajihara, Hirohito Ogawa, Edgar Simulundu, Eugene Bwalya, Yongjin Qiu, Akina Mori-Kajihara, Musso Munyeme, Yoshihiro Sakoda, Takehiko Saito, Bernard M. Hang'ombe, Hirofumi Sawa, Aaron S. Mweene, Ayato Takada
Summary: This study in Zambia identified signs of human influenza virus infections in pig populations, highlighting the need for continued surveillance to monitor the circulation of influenza viruses in swine populations in Africa.
TRANSBOUNDARY AND EMERGING DISEASES
(2022)
Article
Biochemical Research Methods
Ehsan Maleki, Saeedeh Akbari Rokn Abadi, Somayyeh Koohi
Summary: This paper presents a novel all-optical high-throughput method called HELIOS for aligning DNA, RNA, and protein sequences. The HELIOS method utilizes sophisticated operations to locate matches, mutations, and indels within biological sequences, while the optical architecture employs high-speed processing and operational parallelism. Simulation studies confirm that the HELIOS method outperforms both electrical and optical alternatives in terms of processing time and memory requirements.
PLOS COMPUTATIONAL BIOLOGY
(2022)
Article
Microbiology
Rita Zgheib, Issam Hasni, Babacar Mbaye, Hussein Anani, Gabriel Haddad, Nicholas Armstrong, Celine Chartier, Aurelia Caputo, Didier Raoult, Florence Fenollar, Pierre-Edouard Fournier
Summary: This article reports the isolation of a strain called Marseille-P9829 from a bone sample collected from a 46-year-old patient with an open right fibula fracture. Through various methods of classification and identification, it was confirmed that this strain belongs to a new species of Buttiauxella, and a proposed name was suggested.
CURRENT MICROBIOLOGY
(2022)
Article
Computer Science, Interdisciplinary Applications
Xiaohong Pan, Yingming Wang, Kwai-Sang Chin
Summary: This paper presents a dynamic programming algorithm-based picture fuzzy clustering approach to address large-scale group decision-making problems. By defining new picture fuzzy operation laws and weighted geometric operators, proposing a new similarity measure and clustering method, the effectiveness and superiority of the method are demonstrated through an illustrative example and comparative analysis.
COMPUTERS & INDUSTRIAL ENGINEERING
(2021)
