ADAM and ADAMTS family proteins and their role in the colorectal cancer etiopathogenesis

The ADAMTS1 Protease Gene Is Required for Mammary Tumor Growth and Metastasis

(2011) Carmela Ricciardelli et al.   AMERICAN JOURNAL OF PATHOLOGY

Epigenomic Analysis of Aberrantly Methylated Genes in Colorectal Cancer Identifies Genes Commonly Affected by Epigenetic Alterations

(2011) Young-Ho Kim et al.   ANNALS OF SURGICAL ONCOLOGY

Multimerisation of A disintegrin and metalloprotease protein-17 (ADAM17) is mediated by its EGF-like domain

(2011) Inken Lorenzen et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Proteoglycan degradation by the ADAMTS family of proteinases

(2011) Heather Stanton et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

MicroRNA-342 inhibits colorectal cancer cell proliferation and invasion by directly targeting DNA methyltransferase 1

(2011) Hui Wang et al.   CARCINOGENESIS

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

Expression of ADAMTS12 in Colorectal Cancer-Associated Stroma Prevents Cancer Development and Is a Good Prognostic Indicator of Colorectal Cancer

(2011) Da Wang et al.   DIGESTIVE DISEASES AND SCIENCES

Analysis of the disintegrin-metalloproteinases family reveals ADAM29 and ADAM7 are often mutated in melanoma

(2011) Xiaomu Wei et al.   HUMAN MUTATION

Educational level and risk of colorectal cancer in EPIC with specific reference to tumor location

(2011) Anke M. Leufkens et al.   INTERNATIONAL JOURNAL OF CANCER

The cytoplasmic domains of TNFα-converting enzyme (TACE/ADAM17) and L-selectin are regulated differently by p38 MAPK and PKC to promote ectodomain shedding

(2010) David J. Killock et al.   BIOCHEMICAL JOURNAL

Oncogenic Kras Promotes Chemotherapy-Induced Growth Factor Shedding via ADAM17

(2010) S. Van Schaeybroeck et al.   CANCER RESEARCH

Matrix Metalloproteinases: Regulators of the Tumor Microenvironment

(2010) Kai Kessenbrock et al.   CELL

Chemotherapy-Induced Activation of ADAM-17: A Novel Mechanism of Drug Resistance in Colorectal Cancer

(2010) J. N. Kyula et al.   CLINICAL CANCER RESEARCH

Diet and cancer prevention: Contributions from the European Prospective Investigation into Cancer and Nutrition (EPIC) study

(2010) Carlos A. Gonzalez et al.   EUROPEAN JOURNAL OF CANCER

The roles of ADAMTS metalloproteinases in tumorigenesis and metastasis

(2010) Laura Wagstaff   Frontiers in Bioscience-Landmark

ADAM 10 is associated with gastric cancer progression and prognosis of patients

(2010) Yuan-Yu Wang et al.   JOURNAL OF SURGICAL ONCOLOGY

Higher sensitivity of Adamts12-deficient mice to tumor growth and angiogenesis

(2010) M El Hour et al.   ONCOGENE

Distinct Genetic Alterations in Colorectal Cancer

(2010) Hassan Ashktorab et al.   PLoS One

Matrix metalloproteinases: Fold and function of their catalytic domains

(2009) Cynthia Tallant et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Comprehensive Analysis of Reproductive ADAMs: Relationship of ADAM4 and ADAM6 with an ADAM Complex Required for Fertilization in Mice1

(2009) Cecil Han et al.   BIOLOGY OF REPRODUCTION

C-terminal ADAMTS-18 fragment induces oxidative platelet fragmentation, dissolves platelet aggregates, and protects against carotid artery occlusion and cerebral stroke

(2009) Z. Li et al.   BLOOD

High-resolution melting analysis of ADAMTS9 methylation levels in gastric, colorectal, and pancreatic cancers

(2009) Chao Zhang et al.   CANCER GENETICS AND CYTOGENETICS

Genetic Inactivation of ADAMTS15 Metalloprotease in Human Colorectal Cancer

(2009) C. G. Viloria et al.   CANCER RESEARCH

ADAMTS1 and MMP1 proteolytically engage EGF-like ligands in an osteolytic signaling cascade for bone metastasis

(2009) X. Lu et al.   GENES & DEVELOPMENT

The ADAMTS12 metalloprotease gene is epigenetically silenced in tumor cells and transcriptionally activated in the stroma during progression of colon cancer

(2009) A. Moncada-Pazos et al.   JOURNAL OF CELL SCIENCE

Regulation of Mature ADAM17 by Redox Agents for L-Selectin Shedding

(2009) Y. Wang et al.   JOURNAL OF IMMUNOLOGY

Adamalysins in biology and disease

(2009) Harry van Goor et al.   JOURNAL OF PATHOLOGY

High-resolution melting analysis of ADAMTS18 methylation levels in gastric, colorectal and pancreatic cancers

(2009) Zhi Li et al.   MEDICAL ONCOLOGY

Gene methylation profiles of normal mucosa, and benign and malignant colorectal tumors identify early onset markers

(2009) Terje Ahlquist et al.   Molecular Cancer

Autoactivation of human ADAM8: a novel pre-processing step is required for catalytic activity

(2008) Troii Hall et al.   BIOSCIENCE REPORTS

Promoter hypermethylation of theADAM23gene in colorectal cancer cell lines and cancer tissues

(2008) Jin-Sung Choi et al.   INTERNATIONAL JOURNAL OF CANCER

The ADAM metalloproteinases

(2008) D EDWARDS et al.   MOLECULAR ASPECTS OF MEDICINE

Emerging roles of ADAM and ADAMTS metalloproteinases in cancer

(2007) N. Rocks et al.   BIOCHIMIE