Article
Biochemistry & Molecular Biology
Lucia Treppiccione, Francesco Maurano, Stefano Rossi, Diomira Luongo, Mauro Rossi
Summary: Transamidated gliadin can modulate the inflammatory response induced by wheat gliadin in the small intestine of DQ8 mice by regulating both innate and adaptive mechanisms.
Article
Oncology
Theodoros Michelakos, Filippos Kontos, Tomohiro Kurokawa, Lei Cai, Ananthan Sadagopan, Danielle Krijgsman, Wilko Weichert, Lindy G. Durrant, Peter J. K. Kuppen, Cristina R. Ferrone, Soldano Ferrone
Summary: The expression levels of HLA class I loci gene products were found to be associated with various genetic events and survival outcomes in colon and rectal cancer patients. Higher HLA-A expression in rectal tumors treated with neoadjuvant radiation and high HLA-B/C expression levels were independent predictors of favorable overall survival in colon and rectal cancer. T-cells and HLA-B/C antigens appeared to play a key role in controlling the growth of colon/rectal cancer.
JOURNAL FOR IMMUNOTHERAPY OF CANCER
(2022)
Article
Medicine, General & Internal
Biyuan Luo, Fang Ma, Hao Liu, Jixiong Hu, Le Rao, Chun Liu, Yongfang Jiang, Shuyu Kuangzeng, Xuan Lin, Chenyang Wang, Yiyu Lei, Zhongzhou Si, Guangshun Chen, Ning Zhou, Chengbai Liang, Fangqing Jiang, Fenge Liu, Weidong Dai, Wei Liu, Yawen Gao, Zhihong Li, Xi Li, Guangyu Zhou, Bingsi Li, Zhihong Zhang, Weiqi Nian, Lihua Luo, Xianling Liu
Summary: This study developed a sensitive blood-based non-invasive screening model for hepatocellular carcinoma (HCC) that can effectively distinguish early-stage HCC patients from high-risk population, and it demonstrated superior performance in an independent validation cohort.
Article
Dermatology
J. Golinska, M. Sar-Pomian, M. Slawinska, M. Sobjanek, M. Sokolowska-Wojdylo, L. Rudnicka
Summary: This study aimed to compare trichoscopic features in erythroderma of various etiologies and found that different types of vessels and presence of whitish-pinkish structureless areas can indicate the cause of erythroderma.
CLINICAL AND EXPERIMENTAL DERMATOLOGY
(2022)
Article
Clinical Neurology
James Broadley, Robb Wesselingh, Paul Beech, Udaya Seneviratne, Chris Kyndt, Katherine Buzzard, Cassie Nesbitt, Wendyl D'Souza, Amy Brodtmann, Richard Macdonell, Tomas Kalincik, Terence J. O'Brien, Helmut Butzkueven, Mastura Monif
Summary: The utility of neuroimaging characteristics as biomarkers of prognosis in seropositive autoimmune encephalitis (AE) was examined in this study. MRI and PET imaging were assessed, and abnormalities were found in 35.1% and 46.4% of patients, respectively. Initial whole brain and hippocampal volumes were below the 5th and 20th percentile compared to a healthy database. After a median follow-up of 715 days, 85.2% had good functional outcome. Structural and inflammatory changes of the MTL were associated with prognosis in seropositive AE.
NEUROLOGICAL SCIENCES
(2023)
Review
Clinical Neurology
Sule Tinaz
Summary: Accurate and timely diagnosis of atypical parkinsonian syndromes (APS) remains a challenge. However, recent advances in MRI technology have introduced promising imaging modalities to aid in the diagnosis of APS.
FRONTIERS IN NEUROLOGY
(2023)
Article
Computer Science, Information Systems
Mantim Innocent Fale, Ya'u Gita Abdulsalam
Summary: This paper introduces an expert system for differential symptoms-based diagnosis and drug allergy management, and implements corresponding algorithms. Experimental results show that the system has improved prediction accuracy and has potential applications in the field of medical diagnosis and allergy management.
JOURNAL OF KING SAUD UNIVERSITY-COMPUTER AND INFORMATION SCIENCES
(2022)
Article
Immunology
Mingshan Jiang, Zhen Zeng, Kexin Chen, Yuan Dang, Lili Li, Chunxiang Ma, Rui Cheng, Kehan Hu, Xi Li, Hu Zhang
Summary: This study aimed to explore the diagnostic values of enterogeneous microbiotic markers in patients with Crohn's disease (CD), CD concomitant with intestinal tuberculosis (CD-ITB), and intestinal tuberculosis (ITB). The results showed that these markers could accurately differentiate CD patients from healthy controls and had different diagnostic and classification values. Additionally, the levels of these markers were associated with disease severity and the risk of related surgery.
FRONTIERS IN IMMUNOLOGY
(2022)
Article
Dermatology
E. Cinotti, L. Tognetti, M. Campoli, F. Liso, A. Cicigoi, A. Cartocci, R. Rossi, P. Rubegni, J. L. Perrot
Summary: This study compared the features of pigmented cells in naevi and melanomas under D400 magnification dermoscopy, finding that melanomas had more distinct features at D400. The results suggest that D400 may be helpful in the diagnosis of melanoma.
CLINICAL AND EXPERIMENTAL DERMATOLOGY
(2021)
Article
Biology
Kacper Nijakowski, Piotr Eder, Marek Simon, Katarzyna Korybalska, Janusz Witowski, Anna Surdacka
Summary: The study found that the levels of S100A8/calprotectin, myeloperoxidase, and IgA in the saliva of patients with inflammatory bowel disease were significantly decreased. Myeloperoxidase and TNF-R1 concentrations showed high differentiation potential for distinguishing between Crohn's disease and ulcerative colitis.
Article
Hematology
P. Martijn Kolijn, Fatemeh Saberi Hosnijeh, Florentin Spath, Paul J. Hengeveld, Andreas Agathangelidis, Manal Saleh, Delphine Casabonne, Yolanda Benavente, Mats Jerkeman, Antonio Agudo, Aurelio Barricarte, Caroline Besson, Maria-Jose Sanchez, Maria-Dolores Chirlaque, Giovanna Masala, Carlotta Sacerdote, Sara Grioni, Matthias B. Schulze, Alexandra Nieters, Peter Engelfriet, Magnus Hultdin, James D. McKay, Roel C. H. Vermeulen, Anton W. Langerak
Summary: Chronic lymphocytic leukemia (CLL) is preceded by monoclonal B-cell lymphocytosis (MBL), a common condition in aged individuals. In this study, significant skewing in the B-cell receptor (BcR) immunoglobulin heavy chain (IGH) gene repertoire was found in the majority of CLL patients, even before the occurrence of lymphocytosis. Furthermore, some patients already had clonotypes associated with poor prognosis years before diagnosis.
Article
Genetics & Heredity
Neta Aviran, Gil Amarilyo, Yaniv Lakovsky, Rotem Tal, Jenny Garkaby, Rubi Haviv, Yosef Uziel, Shiri Spielman, Hamada Mohammad Natour, Yonatan Herman, Oded Scheuerman, Yonatan Butbul Aviel, Yoel Levinsky, Liora Harel
Summary: This study described the magnetic resonance imaging (MRI) findings of pediatric patients with Protracted Febrile Myalgia Syndrome (PFMS), suggesting that MRI can serve as an auxiliary diagnostic tool in PFMS.
ORPHANET JOURNAL OF RARE DISEASES
(2022)
Article
Clinical Neurology
Daniel Jackson, Donald E. McLawhorn, Sutanaya Pal
Summary: There are patients whose diagnoses are difficult, but accuracy and precision are possible and beneficial for most patients. This is especially true for patients with borderline personality organization who have psychotic symptoms. The concept of borderline personality organization can enrich and provide information for the development of personality disorders.
JOURNAL OF NERVOUS AND MENTAL DISEASE
(2023)
Article
Neurosciences
Alexandra Plonka, Aurelie Mouton, Joel Macoir, Thi-Mai Tran, Alexandre Derremaux, Philippe Robert, Valeria Manera, Auriane Gros
Summary: The study found that writing pressure can differentiate patients with PPA, AD, and healthy subjects in different tasks. However, performance classification depended on the nature of the tasks.
Article
Medicine, General & Internal
Michael Mahler, Kishore Malyavantham, Andrea Seaman, Chelsea Bentow, Ariadna Anunciacion-Llunell, Maria Teresa Sanz-Martinez, Laura Vinas-Gimenez, Albert Selva-O'Callaghan
Summary: The study evaluated the clinical performance and diagnostic value of MSA profiled by PMAT in IIM patients, indicating that MSA, especially when combined in composite scores, provide significant value in stratifying patients with IIM.
Article
Oncology
Tom B. Davidson, Alexander Lee, Melody Hsu, Shaina Sedighim, Joey Orpilla, Janet Treger, Max Mastall, Saskia Roesch, Carmen Rapp, Mildred Galvez, Aaron Mochizuki, Joseph Antonios, Alejandro Garcia, Nikesh Kotecha, Nicholas Bayless, David Nathanson, Anthony Wang, Richard Everson, William H. Yong, Timothy F. Cloughesy, Linda M. Liau, Christel Herold-Mende, Robert M. Prins
CLINICAL CANCER RESEARCH
(2019)
Article
Oncology
Jingwen Yao, Caleb Hock Pang Tan, Jacob Schlossman, Ararat Chakhoyan, Catalina Raymond, Whitney B. Pope, Noriko Salamon, Albert Lai, Matthew Ji, Phioanh L. Nghiemphu, Linda M. Liau, Timothy F. Cloughesy, Benjamin M. Ellingson
JOURNAL OF NEURO-ONCOLOGY
(2019)
Article
Oncology
Fei Liu, Christopher D. Cox, Reshmi Chowdhury, Laura Dovek, Huytram Nguyen, Tie Li, Sichen Li, Byram Ozer, Arthur Chou, Nhung Nguyen, Bowen Wei, Joseph Antonios, Horacio Soto, Harley Kornblum, Linda Liau, Robert Prins, P. Leia Nghiemphu, William Yong, Timothy Cloughesy, Albert Lai
JOURNAL OF NEURO-ONCOLOGY
(2019)
Article
Biochemistry & Molecular Biology
Timothy F. Cloughesy, Aaron Y. Mochizuki, Joey R. Orpilla, Willy Hugo, Alexander H. Lee, Tom B. Davidson, Anthony C. Wang, Benjamin M. Ellingson, Julie A. Rytlewski, Catherine M. Sanders, Eric S. Kawaguchi, Lin Du, Gang Li, William H. Yong, Sarah C. Gaffey, Adam L. Cohen, Ingo K. Mellinghoff, Eudocia Q. Lee, David A. Reardon, Barbara J. O'Brien, Nicholas A. Butowski, Phioanh L. Nghiemphu, Jennifer L. Clarke, Isabel C. Arrillaga-Romany, Howard Colman, Thomas J. Kaley, John F. De Groot, Linda M. Liau, Patrick Y. Wen, Robert M. Prins
Article
Multidisciplinary Sciences
Ararat Chakhoyan, Jingwen Yao, Kevin Leu, Whitney B. Pope, Noriko Salamon, William Yong, Albert Lai, Phioanh L. Nghiemphu, Richard G. Everson, Robert M. Prins, Linda M. Liau, David A. Nathanson, Timothy F. Cloughesy, Benjamin M. Ellingson
SCIENTIFIC REPORTS
(2019)
Article
Clinical Neurology
Y. -L. Wang, J. Yao, A. Chakhoyan, C. Raymond, N. Salamon, L. M. Liau, P. L. Nghiemphu, A. Lai, W. B. Pope, N. Nguyen, M. Ji, T. F. Cloughesy, B. M. Ellingson
AMERICAN JOURNAL OF NEURORADIOLOGY
(2019)
Article
Oncology
Jingwen Yao, Ararat Chakhoyan, David A. Nathanson, William H. Yong, Noriko Salamon, Catalina Raymond, Sergey Mareninov, Albert Lai, Phioanh L. Nghiemphu, Robert M. Prins, Whitney B. Pope, Richard G. Everson, Linda M. Liau, Timothy F. Cloughesy, Benjamin M. Ellingson
Article
Oncology
Andrew McKinney, Olle R. Lindberg, Jane R. Engler, Katharine Y. Chen, Anupam Kumar, Henry Gong, Kan V. Lu, Erin F. Simonds, Timothy F. Cloughesy, Linda M. Liau, Michael Prados, Andrew W. Bollen, Mitchel S. Berger, Joseph T. C. Shieh, C. David James, Theodore P. Nicolaides, William H. Yong, Albert Lai, Monika E. Hegi, William A. Weiss, Joanna J. Phillips
MOLECULAR CANCER THERAPEUTICS
(2019)
Letter
Clinical Neurology
Mary Jane Lim-Fat, Wenya Linda Bi, Janet Lo, Eudocia Quant Lee, Manmeet S. Ahluwalia, Tracy T. Batchelor, Susan M. Chang, E. Antonio Chiocca, Ugonma Chukwueke, Timothy F. Cloughesy, Howard Colman, Lisa M. Deangelis, Evanthia Galanis, Mark R. Gilbert, John F. De Groot, Andrew B. Lassman, Linda M. Liau, Warren Mason, J. Ricardo McFaline-Figueroa, Minesh P. Mehta, Ingo K. Mellinghoff, L. Burt Nabors, Lakshmi Nayak, David A. Reardon, Patrick Y. Wen
Article
Biology
Xuchen Hu, Ken Matsumoto, Rachel S. Jung, Thomas A. Weston, Patrick J. Heizer, Cuiwen He, Norma P. Sandoval, Christopher M. Allan, Yiping Tu, Harry V. Vinters, Linda M. Liau, Rochelle M. Ellison, Jazmin E. Morales, Lynn J. Baufeld, Nicholas A. Bayley, Liqun He, Christer Betsholtz, Anne P. Beigneux, David A. Nathanson, Holger Gerhardt, Stephen G. Young, Loren G. Fong, Haibo Jian
Review
Clinical Neurology
Timothy J. Brown, Daniela A. Bota, Martin J. van den Bent, Paul D. Brown, Elizabeth Maher, Dawit Aregawi, Linda M. Liau, Jan C. Buckner, Michael Weller, Mitchel S. Berger, Michael Glantz
NEURO-ONCOLOGY PRACTICE
(2019)
Article
Clinical Neurology
Laura Dovek, Nhung T. Nguyen, Byram H. Ozer, Ning Li, Robert M. Elashoff, Richard M. Green, Linda Liau, P. Leia Nghiemphu, Timothy F. Cloughesy, Albert Lai
NEURO-ONCOLOGY PRACTICE
(2019)
Article
Radiology, Nuclear Medicine & Medical Imaging
Jingwen Yao, Dan Ruan, Catalina Raymond, Linda M. Liau, Noriko Salamon, Whitney B. Pope, Phioanh L. Nghiemphu, Albert Lai, Timothy F. Cloughesy, Benjamin M. Ellingson
Review
Oncology
Brian M. Alexander, Sujuan Ba, Mitchel S. Berger, Donald A. Berry, Webster K. Cavenee, Susan M. Chang, Timothy F. Cloughesy, Tao Jiang, Mustafa Khasraw, Wenbin Li, Robert Mittman, George H. Poste, Patrick Y. Wen, W. K. Alfred Yung, Anna D. Barker
CLINICAL CANCER RESEARCH
(2018)
Article
Oncology
Lawrance K. Chung, Panayiotis E. Pelargos, Ann M. Chan, Joanna V. Demos, Carlito Lagman, John P. Sheppard, Thien Nguyen, Yu-Ling Chang, Seyed A. Hojat, Robert M. Prins, Linda M. Liau, Leia Nghiemphu, Albert Lai, Timothy F. Cloughesy, William H. Yong, Lynn K. Gordon, Madhuri Wadehra, Isaac Yang
BRAIN TUMOR PATHOLOGY
(2018)