Transcription factor IRF8 plays a critical role in the development of murine basophils and mast cells

Mast cell progenitors: Origin, development and migration to tissues

(2015) Joakim S. Dahlin et al.   MOLECULAR IMMUNOLOGY

The Transcription Factor IRF8 Activates Integrin-Mediated TGF-β Signaling and Promotes Neuroinflammation

(2014) Yuko Yoshida et al.   IMMUNITY

IFN Consensus Sequence Binding Protein (Icsbp) Is Critical for Eosinophil Development

(2014) M. Milanovic et al.   JOURNAL OF IMMUNOLOGY

A Reporter Mouse Reveals Lineage-Specific and Heterogeneous Expression of IRF8 during Lymphoid and Myeloid Cell Differentiation

(2014) Hongsheng Wang et al.   JOURNAL OF IMMUNOLOGY

IRF8 inhibits C/EBPα activity to restrain mononuclear phagocyte progenitors from differentiating into neutrophils

(2014) Daisuke Kurotaki et al.   Nature Communications

Essential role of the IRF8-KLF4 transcription factor cascade in murine monocyte differentiation

(2013) D. Kurotaki et al.   BLOOD

Antagonistic Regulation by the Transcription Factors C/EBPα and MITF Specifies Basophil and Mast Cell Fates

(2013) Xiaopeng Qi et al.   IMMUNITY

The skin is an important bulwark of acquired immunity against intestinal helminths

(2013) Kazushige Obata-Ninomiya et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Inflammatory Flt3l is essential to mobilize dendritic cells and for T cell responses during Plasmodium infection

(2013) Pierre Guermonprez et al.   NATURE MEDICINE

GATA-1 regulates the generation and function of basophils

(2013) Y. Nei et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dynamic self-stiffening in liquid crystal elastomers

(2013) Aditya Agrawal et al.   Nature Communications

PU.1 Level-Directed Chromatin Structure Remodeling at the Irf8 Gene Drives Dendritic Cell Commitment

(2013) Jörg Schönheit et al.   Cell Reports

Critical role of P1-Runx1 in mouse basophil development

(2012) K. Mukai et al.   BLOOD

Role of Mast Cells and Basophils in IgE Responses and in Allergic Airway Hyperresponsiveness

(2012) M. Sawaguchi et al.   JOURNAL OF IMMUNOLOGY

The Ets transcription factor Spi-B is essential for the differentiation of intestinal microfold cells

(2012) Takashi Kanaya et al.   NATURE IMMUNOLOGY

Nonredundant Roles of Basophils in Immunity

(2011) Hajime Karasuyama et al.   Annual Review of Immunology

IRF8Mutations and Human Dendritic-Cell Immunodeficiency

(2011) Sophie Hambleton et al.   NEW ENGLAND JOURNAL OF MEDICINE

Shared and Distinct Functions of the Transcription Factors IRF4 and IRF8 in Myeloid Cell Development

(2011) Michio Yamamoto et al.   PLoS One

Cooperation between deficiencies of IRF-4 and IRF-8 promotes both myeloid and lymphoid tumorigenesis

(2010) S.-H. Jo et al.   BLOOD

Distinguishing Mast Cell and Granulocyte Differentiation at the Single-Cell Level

(2010) Christopher B. Franco et al.   Cell Stem Cell

Basophils Orchestrate Chronic Allergic Dermatitis and Protective Immunity against Helminths

(2010) Caspar Ohnmacht et al.   IMMUNITY

Development of Monocytes, Macrophages, and Dendritic Cells

(2010) F. Geissmann et al.   SCIENCE

Mast Cell-Mediated Antigen Presentation Regulates CD8+ T Cell Effector Functions

(2009) Erietta Stelekati et al.   IMMUNITY

IL-3 Induces Basophil Expansion In Vivo by Directing Granulocyte-Monocyte Progenitors to Differentiate into Basophil Lineage-Restricted Progenitors in the Bone Marrow and by Increasing the Number of Basophil/Mast Cell Progenitors in the Spleen

(2009) K. Ohmori et al.   JOURNAL OF IMMUNOLOGY

The IRF Family Transcription Factors in Immunity and Oncogenesis

(2008) Tomohiko Tamura et al.   Annual Review of Immunology

Hematopoiesis: An Evolving Paradigm for Stem Cell Biology

(2008) Stuart H. Orkin et al.   CELL

Basophils Play a Pivotal Role in Immunoglobulin-G-Mediated but Not Immunoglobulin-E-Mediated Systemic Anaphylaxis

(2008) Yusuke Tsujimura et al.   IMMUNITY

The Signal Transducer STAT5 Inhibits Plasmacytoid Dendritic Cell Development by Suppressing Transcription Factor IRF8

(2008) Eiji Esashi et al.   IMMUNITY

The Immunological Genome Project: networks of gene expression in immune cells

(2008) Tracy S P Heng et al.   NATURE IMMUNOLOGY