KLF1 mutations are relatively more common in a thalassemia endemic region and ameliorate the severity of  -thalassemia

Mutations in Kruppel-like factor 1 cause transfusion-dependent hemolytic anemia and persistence of embryonic globin gene expression

(2014) V. Viprakasit et al.   BLOOD

KLF1Gene Mutations in Chinese Adults with Increased Fetal Hemoglobin

(2013) Ting Wang et al.   HEMOGLOBIN

A novel 519_525dup mutation ofKLF1gene identified in a Chinese blood donor with Lu(a-b-) phenotype

(2013) Zhen Wang et al.   TRANSFUSION

The Search for Genetic Modifiers of Disease Severity in the  -Hemoglobinopathies

(2013) G. Lettre   Cold Spring Harbor Perspectives in Medicine

The Switch from Fetal to Adult Hemoglobin

(2013) V. G. Sankaran et al.   Cold Spring Harbor Perspectives in Medicine

The Molecular Basis of  -Thalassemia

(2013) S. L. Thein   Cold Spring Harbor Perspectives in Medicine

Genetic association studies in  -hemoglobinopathies

(2013) S. L. Thein   Hematology-American Society of Hematology Education Program

Novel roles for KLF1 in erythropoiesis revealed by mRNA-seq

(2012) M. R. Tallack et al.   GENOME RESEARCH

Molecular Analysis of the Rare In(Lu) Blood Type: Toward Decoding the Phenotypic Outcome of Haploinsufficiency for the Transcription Factor KLF1

(2012) Virginie Helias et al.   HUMAN MUTATION

Seventy-five genetic loci influencing the human red blood cell

(2012) Pim van der Harst et al.   NATURE

The multifunctional role of EKLF/KLF1 during erythropoiesis

(2011) M. Siatecka et al.   BLOOD

Mutations in the second zinc finger of human EKLF reduce promoter affinity but give rise to benign and disease phenotypes

(2011) B. K. Singleton et al.   BLOOD

A 3-bp deletion in the HBS1L-MYB intergenic region on chromosome 6q23 is associated with HbF expression

(2011) J. J. Farrell et al.   BLOOD

KLF1 gene mutations cause borderline HbA2

(2011) L. Perseu et al.   BLOOD

Compound heterozygosity for KLF1 mutations associated with remarkable increase of fetal hemoglobin and red cell protoporphyrin

(2011) S. Satta et al.   HAEMATOLOGICA

Ten novel mutations in the erythroid transcription factor KLF1 gene associated with increased fetal hemoglobin levels in adults

(2011) A. E. Gallienne et al.   HAEMATOLOGICA

Erythroid phenotypes associated with KLF1 mutations

(2011) J. Borg et al.   HAEMATOLOGICA

Thalassaemia

(2011) Douglas R Higgs et al.   LANCET

A Dominant Mutation in the Gene Encoding the Erythroid Transcription Factor KLF1 Causes a Congenital Dyserythropoietic Anemia

(2010) Lionel Arnaud et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Molecular epidemiological survey of haemoglobinopathies in the Guangxi Zhuang Autonomous Region of southern China

(2010) F Xiong et al.   CLINICAL GENETICS

Haploinsufficiency for the erythroid transcription factor KLF1 causes hereditary persistence of fetal hemoglobin

(2010) Joseph Borg et al.   NATURE GENETICS

KLF1 regulates BCL11A expression and γ- to β-globin gene switching

(2010) Dewang Zhou et al.   NATURE GENETICS

Fine-mapping at three loci known to affect fetal hemoglobin levels explains additional genetic variation

(2010) Geneviève Galarneau et al.   NATURE GENETICS

Amelioration of Sardinian  0 thalassemia by genetic modifiers

(2009) R. Galanello et al.   BLOOD

Complications and treatment of patients with  -thalassemia in France: results of the National Registry

(2009) I. Thuret et al.   HAEMATOLOGICA

Development and validation of a  -globin-specific ELISA for carrier screening of the (--SEA)   thalassaemia deletion

(2009) L Tang et al.   JOURNAL OF CLINICAL PATHOLOGY

Mutations in EKLF/KLF1 form the molecular basis of the rare blood group In(Lu) phenotype

(2008) B. K. Singleton et al.   BLOOD

Genome-wide association study shows BCL11A associated with persistent fetal hemoglobin and amelioration of the phenotype of  -thalassemia

(2008) M. Uda et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA