IKK-dependent activation of NF- B contributes to myeloid and lymphoid leukemogenesis by BCR-ABL1

Differential regulation of myeloid leukemias by the bone marrow microenvironment

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Essential role for Stat5a/b in myeloproliferative neoplasms induced by BCR-ABL1 and JAK2V617F in mice

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Navigating the road toward optimal initial therapy for chronic myeloid leukemia

(2011) Ross A Okimoto et al.   CURRENT OPINION IN HEMATOLOGY

Bortezomib induces apoptosis in primitive chronic myeloid leukemia cells including LTC-IC and NOD/SCID repopulating cells

(2010) N. B. Heaney et al.   BLOOD

Human chronic myeloid leukemia stem cells are insensitive to imatinib despite inhibition of BCR-ABL activity

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Discontinuation of imatinib in patients with chronic myeloid leukaemia who have maintained complete molecular remission for at least 2 years: the prospective, multicentre Stop Imatinib (STIM) trial

(2010) François-Xavier Mahon et al.   LANCET ONCOLOGY

Bortezomib decreases Rb phosphorylation and induces caspase-dependent apoptosis in Imatinib-sensitive and -resistant Bcr-Abl1-expressing cells

(2010) M P Albero et al.   ONCOGENE

IKKα and IKKβ Each Function to Regulate NF-κB Activation in the TNF-Induced/Canonical Pathway

(2010) Mazhar Adli et al.   PLoS One

Changing Paradigm of the Treatment of Philadelphia Chromosome–Positive Acute Lymphoblastic Leukemia

(2010) Ryuzo Ohno   Current Hematologic Malignancy Reports

Proteasome Inhibition Causes Regression of Leukemia and Abrogates BCR-ABL-Induced Evasion of Apoptosis in Part through Regulation of Forkhead Tumor Suppressors

(2009) Z. Jagani et al.   CANCER RESEARCH

NF-κB inhibition triggers death of imatinib-sensitive and imatinib-resistant chronic myeloid leukemia cells including T315I Bcr-Abl mutants

(2009) Nadia Lounnas et al.   INTERNATIONAL JOURNAL OF CANCER

ELDA: Extreme limiting dilution analysis for comparing depleted and enriched populations in stem cell and other assays

(2009) Yifang Hu et al.   JOURNAL OF IMMUNOLOGICAL METHODS

Molecular biology of bcr-abl1-positive chronic myeloid leukemia

(2008) A. Quintas-Cardama et al.   BLOOD

Nuclear factor-κB as a potential therapeutic target for the novel cytotoxic agent LC-1 in acute myeloid leukaemia

(2008) Christopher Jenkins et al.   BRITISH JOURNAL OF HAEMATOLOGY

I B kinase   inhibition induces cell death in Imatinib-resistant and T315I Dasatinib-resistant BCR-ABL+ cells

(2008) E. A. Duncan et al.   MOLECULAR CANCER THERAPEUTICS