The enhancer and promoter landscape of human regulatory and conventional T-cell subpopulations

Transcription and enhancer profiling in human monocyte subsets

(2014) C. Schmidl et al.   BLOOD

A promoter-level mammalian expression atlas

(2014)   NATURE

Functionally distinct subsets of human FOXP3+ Treg cells that phenotypically mirror effector Th cells

(2012) T. Duhen et al.   BLOOD

Dynamic epigenetic enhancer signatures reveal key transcription factors associated with monocytic differentiation states

(2012) T.-H. Pham et al.   BLOOD

Foxp3 Exploits a Pre-Existent Enhancer Landscape for Regulatory T Cell Lineage Specification

(2012) Robert M. Samstein et al.   CELL

Landscape of transcription in human cells

(2012) Sarah Djebali et al.   NATURE

Transcription factor Foxp3 and its protein partners form a complex regulatory network

(2012) Dipayan Rudra et al.   NATURE IMMUNOLOGY

A Spontaneous Mutation of the Rat Themis Gene Leads to Impaired Function of Regulatory T Cells Linked to Inflammatory Bowel Disease

(2012) Marianne Chabod et al.   PLoS Genetics

Regulatory T cells in stem cell transplantation: strategies and first clinical experiences

(2011) Matthias Edinger et al.   CURRENT OPINION IN IMMUNOLOGY

Epigenetic reprogramming of the RORC locus during in vitro expansion is a distinctive feature of human memory but not naïve Treg

(2011) Christian Schmidl et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Unamplified cap analysis of gene expression on a single-molecule sequencer

(2011) M. Kanamori-Katayama et al.   GENOME RESEARCH

Dominant Th2 Differentiation of Human Regulatory T Cells upon Loss of FOXP3 Expression

(2011) L. Hansmann et al.   JOURNAL OF IMMUNOLOGY

Repression of the genome organizer SATB1 in regulatory T cells is required for suppressive function and inhibition of effector differentiation

(2011) Marc Beyer et al.   NATURE IMMUNOLOGY

Next-generation insights into regulatory T cells: expression profiling and FoxP3 occupancy in Human

(2011) Fabian Birzele et al.   NUCLEIC ACIDS RESEARCH

Function of miR-146a in Controlling Treg Cell-Mediated Regulation of Th1 Responses

(2010) Li-Fan Lu et al.   CELL

The Ets-1 transcription factor controls the development and function of natural regulatory T cells

(2010) Enguerran Mouly et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Methylation matters: binding of Ets-1 to the demethylated Foxp3 gene contributes to the stabilization of Foxp3 expression in regulatory T cells

(2010) Julia K. Polansky et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Simple Combinations of Lineage-Determining Transcription Factors Prime cis-Regulatory Elements Required for Macrophage and B Cell Identities

(2010) Sven Heinz et al.   MOLECULAR CELL

A unique chromatin signature uncovers early developmental enhancers in humans

(2010) Alvaro Rada-Iglesias et al.   NATURE

In vivo prevention of transplant arteriosclerosis by ex vivo–expanded human regulatory T cells

(2010) Satish N Nadig et al.   NATURE MEDICINE

The STRING database in 2011: functional interaction networks of proteins, globally integrated and scored

(2010) D. Szklarczyk et al.   NUCLEIC ACIDS RESEARCH

Histone H3K27ac separates active from poised enhancers and predicts developmental state

(2010) M. P. Creyghton et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genomic definition of multiple ex vivo regulatory T cell subphenotypes

(2010) M. Feuerer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

edgeR: a Bioconductor package for differential expression analysis of digital gene expression data

(2009) M. D. Robinson et al.   BIOINFORMATICS

Loss of FOXP3 expression in natural human CD4+CD25+regulatory T cells upon repetitivein vitrostimulation

(2009) Petra Hoffmann et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Lineage-specific DNA methylation in T cells correlates with histone methylation and enhancer activity

(2009) C. Schmidl et al.   GENOME RESEARCH

Indispensable Role of the Runx1-Cbfβ Transcription Complex for In Vivo-Suppressive Function of FoxP3+ Regulatory T Cells

(2009) Akihiko Kitoh et al.   IMMUNITY

Functional Delineation and Differentiation Dynamics of Human CD4+ T Cells Expressing the FoxP3 Transcription Factor

(2009) Makoto Miyara et al.   IMMUNITY

Runx proteins regulate Foxp3 expression

(2009) Ludovica Bruno et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Histone modifications at human enhancers reflect global cell-type-specific gene expression

(2009) Nathaniel D. Heintzman et al.   NATURE

Regulatory T-cell suppressor program co-opts transcription factor IRF4 to control TH2 responses

(2009) Ye Zheng et al.   NATURE

The transcription factor T-bet controls regulatory T cell homeostasis and function during type 1 inflammation

(2009) Meghan A Koch et al.   NATURE IMMUNOLOGY

Human memory FOXP3+ Tregs secrete IL-17 ex vivo and constitutively express the TH17 lineage-specific transcription factor ROR t

(2009) M. Ayyoub et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

CD4+ Regulatory T Cells Control TH17 Responses in a Stat3-Dependent Manner

(2009) A. Chaudhry et al.   SCIENCE

Methods for analyzing deep sequencing expression data: constructing the human and mouse promoterome with deepCAGE data

(2009) Piotr J Balwierz et al.   GENOME BIOLOGY

Human regulatory T cells: role in autoimmune disease and therapeutic opportunities

(2008) Todd M. Brusko et al.   IMMUNOLOGICAL REVIEWS