STXBP1 promotes Weibel-Palade body exocytosis through its interaction with the Rab27A effector Slp4-a

Analysis of the storage and secretion of von Willebrand factor in blood outgrowth endothelial cells derived from patients with von Willebrand disease

(2013) J.-W. Wang et al.   BLOOD

Reduction of seizure frequency after epilepsy surgery in a patient withSTXBP1encephalopathy and clinical description of six novel mutation carriers

(2013) Sarah Weckhuysen et al.   EPILEPSIA

Characterisation of Weibel-Palade body fusion by amperometry in endothelial cells reveals fusion pore dynamics and the effect of cholesterol on exocytosis

(2013) E. A. Cookson et al.   JOURNAL OF CELL SCIENCE

Phosphatidylinositol-3,4,5-triphosphate-dependent Rac exchange factor 1 regulates epinephrine-induced exocytosis of Weibel-Palade bodies

(2013) K. W. E. M. van Hooren et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Rab27 Effectors, Pleiotropic Regulators in Secretory Pathways

(2013) Mitsunori Fukuda   TRAFFIC

The interplay between the Rab27A effectors Slp4-a and MyRIP controls hormone-evoked Weibel-Palade body exocytosis

(2012) R. Bierings et al.   BLOOD

Munc18-1 Regulates First-phase Insulin Release by Promoting Granule Docking to Multiple Syntaxin Isoforms

(2012) Eunjin Oh et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Epac-Rap1 Signaling Pathway Controls cAMP-mediated Exocytosis of Weibel-Palade Bodies in Endothelial Cells

(2012) Kathinka W. E. M. van Hooren et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A complete Rab screening reveals novel insights in Weibel-Palade body exocytosis

(2012) S. Zografou et al.   JOURNAL OF CELL SCIENCE

Proteomic Screen Identifies IGFBP7 as a Novel Component of Endothelial Cell-Specific Weibel-Palade Bodies

(2012) Dorothee van Breevoort et al.   JOURNAL OF PROTEOME RESEARCH

Molecular machines governing exocytosis of synaptic vesicles

(2012) Reinhard Jahn et al.   NATURE

Synaptotagmin-like proteins control the formation of a single apical membrane domain in epithelial cells

(2012) Manuel Gálvez-Santisteban et al.   NATURE CELL BIOLOGY

Establishment of outgrowth endothelial cells from peripheral blood

(2012) Javier Martin-Ramirez et al.   Nature Protocols

The Shear Stress-Induced Transcription Factor KLF2 Affects Dynamics and Angiopoietin-2 Content of Weibel-Palade Bodies

(2012) Ellen L. van Agtmaal et al.   PLoS One

Effect of Genetic Variation in STXBP5 and STX2 on von Willebrand Factor and Bleeding Phenotype in Type 1 von Willebrand Disease Patients

(2012) Janine E. van Loon et al.   PLoS One

CD63 is an essential cofactor to leukocyte recruitment by endothelial P-selectin

(2011) E. L. Doyle et al.   BLOOD

Myosin Va Acts in Concert with Rab27a and MyRIP to Regulate Acute Von-Willebrand Factor Release from Endothelial Cells

(2011) Inés Rojo Pulido et al.   TRAFFIC

VAMP3 is associated with endothelial Weibel–Palade bodies and participates in their Ca2+-dependent exocytosis

(2010) Inés Rojo Pulido et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Endothelial von Willebrand factor regulates angiogenesis

(2010) R. D. Starke et al.   BLOOD

Genetic variation associated with plasma von Willebrand factor levels and the risk of incident venous thrombosis

(2010) N. L. Smith et al.   BLOOD

A revised model for the secretion of tPA and cytokines from cultured endothelial cells

(2010) L. Knipe et al.   BLOOD

Novel Associations of Multiple Genetic Loci With Plasma Levels of Factor VII, Factor VIII, and von Willebrand Factor

(2010) Nicholas L. Smith et al.   CIRCULATION

Effect of Genetic Variations in Syntaxin-Binding Protein-5 and Syntaxin-2 on von Willebrand Factor Concentration and Cardiovascular Risk

(2010) Janine E. van Loon et al.   Circulation-Cardiovascular Genetics

A role for Rab10 in von Willebrand factor release discovered by an AP-1 interactor screen in C. elegans

(2010) G. MICHAUX et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Clinical spectrum of early-onset epileptic encephalopathies associated with STXBP1 mutations

(2010) L. Deprez et al.   NEUROLOGY

Rab27a and MyRIP regulate the amount and multimeric state of VWF released from endothelial cells

(2009) T. D. Nightingale et al.   BLOOD

Basal secretion of von Willebrand factor from human endothelial cells

(2008) J. P. Giblin et al.   BLOOD

Guanine exchange factor RalGDS mediates exocytosis of Weibel-Palade bodies from endothelial cells

(2008) M. G. Rondaij et al.   BLOOD

De novo mutations in the gene encoding STXBP1 (MUNC18-1) cause early infantile epileptic encephalopathy

(2008) Hirotomo Saitsu et al.   NATURE GENETICS

Munc 18-1 and Granuphilin Collaborate During Insulin Granule Exocytosis

(2008) Alejandra Tomas et al.   TRAFFIC