A conditional knockout mouse model reveals endothelial cells as the principal and possibly exclusive source of plasma factor VIII

Human liver sinusoidal endothelial cells but not hepatocytes contain factor VIII

(2013) T. Shahani et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

The intimate relationships of mRNA decay and translation

(2013) Bijoyita Roy et al.   TRENDS IN GENETICS

Role of bone marrow transplantation for correcting hemophilia A in mice

(2012) A. Follenzi et al.   BLOOD

Mesenchymal stem cells contribute to endogenous FVIII:c production

(2012) Chad Sanada et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Hemogenic endothelium: Origins, regulation, and implications for vascular biology

(2011) Joan P. Zape et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Factor VIII Can Be Synthesized in Hemophilia A Mice Liver by Bone Marrow Progenitor Cell-Derived Hepatocytes and Sinusoidal Endothelial Cells

(2011) Neelam Yadav et al.   STEM CELLS AND DEVELOPMENT

Antibody validation

(2010) Jennifer Bordeaux et al.   BIOTECHNIQUES

Activation of human endothelial cells from specific vascular beds induces the release of a FVIII storage pool

(2010) T. Shahani et al.   BLOOD

Sustained factor VIII production in hemophiliac mice 1 year after engraftment with induced pluripotent stem cell-derived factor VIII producing endothelial cells

(2010) Zaida Alipio et al.   BLOOD COAGULATION & FIBRINOLYSIS

Endothelial Cell Processing and Alternatively Spliced Transcripts of Factor VIII: Potential Implications for Coagulation Cascades and Pulmonary Hypertension

(2010) Claire L. Shovlin et al.   PLoS One

Extrahepatic factor VIII production in transplant recipient of hemophilia donor liver

(2009) C. L. Madeira et al.   BLOOD

Decoding the Hemogenic Endothelium in Mammals

(2009) Françoise Dieterlen-Lièvre et al.   Cell Stem Cell

Cellular organization of normal mouse liver: a histological, quantitative immunocytochemical, and fine structural analysis

(2009) Janie L. Baratta et al.   HISTOCHEMISTRY AND CELL BIOLOGY

Runx1 is required for the endothelial to haematopoietic cell transition but not thereafter

(2009) Michael J. Chen et al.   NATURE

Phenotypic correction of murine hemophilia A using an iPS cell-based therapy

(2009) Dan Xu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Syngeneic transplantation of hematopoietic stem cells that are genetically modified to express factor VIII in platelets restores hemostasis to hemophilia A mice with preexisting FVIII immunity

(2008) Q. Shi et al.   BLOOD

Mouse consomic strains: Exploiting genetic divergence between Mus m. musculus and Mus m. domesticus subspecies

(2008) S. Gregorova et al.   GENOME RESEARCH

Germ line activation of the Tie2 and SMMHC promoters causes noncell-specific deletion of floxed alleles

(2008) Willem J. de Lange et al.   PHYSIOLOGICAL GENOMICS