HLA-DRB1*07:01 is associated with a higher risk of asparaginase allergies

Coding Variants at Hexa-allelic Amino Acid 13 of HLA-DRB1 Explain Independent SNP Associations with Follicular Lymphoma Risk

(2013) Jia Nee Foo et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Next Generation Sequencing Reveals the Association of DRB3*02:02 With Type 1 Diabetes

(2013) H. A. Erlich et al.   DIABETES

Imputing Amino Acid Polymorphisms in Human Leukocyte Antigens

(2013) Xiaoming Jia et al.   PLoS One

Multi-Population Classical HLA Type Imputation

(2013) Alexander Dilthey et al.   PLoS Computational Biology

Interrogating the major histocompatibility complex with high-throughput genomics

(2012) P. I. W. de Bakker et al.   HUMAN MOLECULAR GENETICS

Clinical utility and implications of asparaginase antibodies in acute lymphoblastic leukemia

(2012) C Liu et al.   LEUKEMIA

Five amino acids in three HLA proteins explain most of the association between MHC and seropositive rheumatoid arthritis

(2012) Soumya Raychaudhuri et al.   NATURE GENETICS

Anti-Escherichia coli asparaginase antibody levels determine the activity of second-line treatment with pegylated E coli asparaginase: a retrospective analysis within the ALL-BFM trials

(2011) A. Willer et al.   BLOOD

Empirical evaluations of analytical issues arising from predicting HLA alleles using multiple SNPs

(2011) Xinyi Zhang et al.   BMC GENETICS

Human leukocyte antigen class II molecules confer both susceptibility and progression in Japanese patients with primary biliary cirrhosis

(2011) Takeji Umemura et al.   HEPATOLOGY

The MHC, disease and selection

(2011) John Trowsdale   IMMUNOLOGY LETTERS

HLA-DQA1*02:01 Is a Major Risk Factor for Lapatinib-Induced Hepatotoxicity in Women With Advanced Breast Cancer

(2011) Colin F. Spraggs et al.   JOURNAL OF CLINICAL ONCOLOGY

Pharmacogenetics and the immunogenicity of protein therapeutics

(2011) Chen Yanover et al.   NATURE BIOTECHNOLOGY

Ancestry and pharmacogenomics of relapse in acute lymphoblastic leukemia

(2011) Jun J Yang et al.   NATURE GENETICS

HLA-A*3101 and Carbamazepine-Induced Hypersensitivity Reactions in Europeans

(2011) Mark McCormack et al.   NEW ENGLAND JOURNAL OF MEDICINE

Augmented therapy improves outcome for pediatric high risk acute lymphocytic leukemia: Results of Children's Oncology Group trial P9906

(2011) W. Paul Bowman et al.   PEDIATRIC BLOOD & CANCER

Single-nucleotide polymorphisms in HLA- and non-HLA genes associated with the development of antibodies to interferon-β therapy in multiple sclerosis patients

(2011) F Weber et al.   PHARMACOGENOMICS JOURNAL

Accelerating Protein Docking in ZDOCK Using an Advanced 3D Convolution Library

(2011) Brian G. Pierce et al.   PLoS One

Therapeutic enzyme deimmunization by combinatorial T-cell epitope removal using neutral drift

(2011) J. R. Cantor et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Peptide binding predictions for HLA DR, DP and DQ molecules

(2010) Peng Wang et al.   BMC BIOINFORMATICS

Genetic Variations in GRIA1 on Chromosome 5q33 Related to Asparaginase Hypersensitivity

(2010) S-H Chen et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Tolerability and Efficacy of L-Asparaginase Therapy in Pediatric Patients With Acute Lymphoblastic Leukemia

(2010) Elizabeth A. Raetz et al.   JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY

HIV-1-Specific Interleukin-21+ CD4+ T Cell Responses Contribute to Durable Viral Control through the Modulation of HIV-Specific CD8+ T Cell Function

(2010) M. F. Chevalier et al.   JOURNAL OF VIROLOGY

Transcriptional Profiling of CD4 T Cells Identifies Distinct Subgroups of HIV-1 Elite Controllers

(2010) F. Vigneault et al.   JOURNAL OF VIROLOGY

Shared molecular amino acid signature in the HLA-DR peptide binding pocket predisposes to both autoimmune diabetes and thyroiditis

(2010) F. Menconi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Bidirectional binding of invariant chain peptides to an MHC class II molecule

(2010) S. Gunther et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Sub-angstrom modeling of complexes between flexible peptides and globular proteins

(2010) Barak Raveh et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

The Major Genetic Determinants of HIV-1 Control Affect HLA Class I Peptide Presentation

(2010)   SCIENCE

A Unified Approach to Genotype Imputation and Haplotype-Phase Inference for Large Data Sets of Trios and Unrelated Individuals

(2009) Brian L. Browning et al.   AMERICAN JOURNAL OF HUMAN GENETICS

An extension to a statistical approach for family based association studies provides insights into genetic risk factors for multiple sclerosis in the HLA-DRB1gene

(2009) Sreeram V Ramagopalan et al.   BMC Medical Genetics

Tryptase Is Not Cleared by the Kidneys into the Urine

(2009) Michael R. Simon et al.   INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY

Germline genomic variants associated with childhood acute lymphoblastic leukemia

(2009) Lisa R Treviño et al.   NATURE GENETICS

The Immune Epitope Database 2.0

(2009) Randi Vita et al.   NUCLEIC ACIDS RESEARCH

Strong association between HLA-B*5801 and allopurinol-induced Stevens–Johnson syndrome and toxic epidermal necrolysis in a Thai population

(2009) Wichittra Tassaneeyakul et al.   Pharmacogenetics and Genomics

Pharmacokinetic, pharmacodynamic and intracellular effects of PEG-asparaginase in newly diagnosed childhood acute lymphoblastic leukemia: results from a single agent window study

(2008) I M Appel et al.   LEUKEMIA

The IMGT/HLA database

(2008) J. Robinson et al.   NUCLEIC ACIDS RESEARCH

HLA-B locus in Japanese patients with anti-epileptics and allopurinol-related Stevens–Johnson syndrome and toxic epidermal necrolysis

(2008) Nahoko Kaniwa et al.   PHARMACOGENOMICS

A Systematic Assessment of MHC Class II Peptide Binding Predictions and Evaluation of a Consensus Approach

(2008) Peng Wang et al.   PLoS Computational Biology