How I treat older patients with ALL

Time from diagnosis to intensive chemotherapy initiation does not adversely impact the outcome of patients with acute myeloid leukemia

(2013) S. Bertoli et al.   BLOOD

Long-term follow-up of hematologic relapse-free survival in a phase 2 study of blinatumomab in patients with MRD in B-lineage ALL

(2012) M. S. Topp et al.   BLOOD

Pediatric acute lymphoblastic leukemia: where are we going and how do we get there?

(2012) C.-H. Pui et al.   BLOOD

Adult patients with acute lymphoblastic leukemia and molecular failure display a poor prognosis and are candidates for stem cell transplantation and targeted therapies

(2012) N. Gokbuget et al.   BLOOD

Outcomes in older adults with acute lymphoblastic leukaemia (ALL): results from the international MRC UKALL XII/ECOG2993 trial

(2012) Jonathan I. Sive et al.   BRITISH JOURNAL OF HAEMATOLOGY

Adult acute lymphoblastic leukaemia in Denmark. A national population-based retrospective study on acute lymphoblastic leukaemia in Denmark 1998-2008

(2012) Nina Toft et al.   BRITISH JOURNAL OF HAEMATOLOGY

High-Dose Vincristine Sulfate Liposome Injection for Advanced, Relapsed, and Refractory Adult Philadelphia Chromosome–Negative Acute Lymphoblastic Leukemia

(2012) Susan O'Brien et al.   JOURNAL OF CLINICAL ONCOLOGY

Inotuzumab ozogamicin, an anti-CD22–calecheamicin conjugate, for refractory and relapsed acute lymphocytic leukaemia: a phase 2 study

(2012) Hagop Kantarjian et al.   LANCET ONCOLOGY

Most 70- to 79-year-old patients with acute myeloid leukemia do benefit from intensive treatment

(2011) G. Juliusson et al.   BLOOD

High single-drug activity of nelarabine in relapsed T-lymphoblastic leukemia/lymphoma offers curative option with subsequent stem cell transplantation

(2011) N. Gokbuget et al.   BLOOD

Dasatinib as first-line treatment for adult patients with Philadelphia chromosome-positive acute lymphoblastic leukemia

(2011) R. Foa et al.   BLOOD

Chemoimmunotherapy in acute lymphoblastic leukemia

(2011) Dieter Hoelzer et al.   BLOOD REVIEWS

Predicting the risk of chemotherapy toxicity in older patients: The Chemotherapy Risk Assessment Scale for High-Age Patients (CRASH) score

(2011) Martine Extermann et al.   CANCER

Therapy-related acute lymphoblastic leukemia is more frequent than previously recognized and has a poor prognosis

(2011) Amal Abdulwahab et al.   CANCER

Optimal Pharmacotherapeutic Management of Acute Lymphoblastic Leukaemia in the Elderly

(2011) Philippe Rousselot et al.   DRUGS & AGING

Non-myeloablative conditioning with allogeneic hematopoietic cell transplantation for the treatment of high-risk acute lymphoblastic leukemia

(2011) R. Ram et al.   HAEMATOLOGICA

Effect of azole antifungal therapy on vincristine toxicity in childhood acute lymphoblastic leukaemia

(2011) R. M. van Schie et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Modern Therapy of Acute Lymphoblastic Leukemia

(2011) Renato Bassan et al.   JOURNAL OF CLINICAL ONCOLOGY

Prediction of Early Death After Induction Therapy for Newly Diagnosed Acute Myeloid Leukemia With Pretreatment Risk Scores: A Novel Paradigm for Treatment Assignment

(2011) Roland B. Walter et al.   JOURNAL OF CLINICAL ONCOLOGY

Targeted Therapy With the T-Cell–Engaging Antibody Blinatumomab of Chemotherapy-Refractory Minimal Residual Disease in B-Lineage Acute Lymphoblastic Leukemia Patients Results in High Response Rate and Prolonged Leukemia-Free Survival

(2011) Max S. Topp et al.   JOURNAL OF CLINICAL ONCOLOGY

Predicting Chemotherapy Toxicity in Older Adults With Cancer: A Prospective Multicenter Study

(2011) Arti Hurria et al.   JOURNAL OF CLINICAL ONCOLOGY

Implementing a Geriatric Assessment in Cooperative Group Clinical Cancer Trials: CALGB 360401

(2011) Arti Hurria et al.   JOURNAL OF CLINICAL ONCOLOGY

Polypharmacy in elderly patients with cancer: clinical implications and management

(2011) Judith Lees et al.   LANCET ONCOLOGY

Subdural hematomas in patients with Philadelphia chromosome-positive acute lymphoblastic leukemia receiving imatinib mesylate in conjunction with systemic and intrathecal chemotherapy

(2011) Shiven B. Patel et al.   LEUKEMIA & LYMPHOMA

Optimal central nervous system prophylaxis in Philadelphia chromosome-positive acute lymphoblastic leukemia: collateral damage in the imatinib era?

(2011) Renato Bassan   LEUKEMIA & LYMPHOMA

Population-based analyses in adult acute lymphoblastic leukemia

(2010) G. Juliusson et al.   BLOOD

Reduced-intensity versus conventional myeloablative conditioning allogeneic stem cell transplantation for patients with acute lymphoblastic leukemia: a retrospective study from the European Group for Blood and Marrow Transplantation

(2010) M. Mohty et al.   BLOOD

The outcome of full-intensity and reduced-intensity conditioning matched sibling or unrelated donor transplantation in adults with Philadelphia chromosome-negative acute lymphoblastic leukemia in first and second complete remission

(2010) D. I. Marks et al.   BLOOD

Potential Medication Problems in Older Newly Diagnosed Cancer Patients in Canada during Cancer Treatment

(2010) Martine T.E. Puts et al.   DRUGS & AGING

Questionnaires and instruments for a multidimensional assessment of the older cancer patient: What clinicians need to know?

(2010) A.G. Pallis et al.   EUROPEAN JOURNAL OF CANCER

Acute lymphoblastic leukemia in the elderly

(2010) A. Delannoy et al.   EUROPEAN JOURNAL OF HAEMATOLOGY

Liposomal cytarabine is effective and tolerable in the treatment of central nervous system relapse of acute lymphoblastic leukemia and very aggressive lymphoma

(2010) N. Gokbuget et al.   HAEMATOLOGICA

A randomized study of pegylated liposomal doxorubicin versus continuous-infusion doxorubicin in elderly patients with acute lymphoblastic leukemia: the GRAALL-SA1 study

(2010) M. Hunault-Berger et al.   HAEMATOLOGICA

Results of comprehensive geriatric assessment effect survival in patients with malignant lymphoma

(2010) Nils Winkelmann et al.   JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY

Chemoimmunotherapy With a Modified Hyper-CVAD and Rituximab Regimen Improves Outcome in De Novo Philadelphia Chromosome–Negative Precursor B-Lineage Acute Lymphoblastic Leukemia

(2010) Deborah A. Thomas et al.   JOURNAL OF CLINICAL ONCOLOGY

Complete remission and early death after intensive chemotherapy in patients aged 60 years or older with acute myeloid leukaemia: a web-based application for prediction of outcomes

(2010) Utz Krug et al.   LANCET

A population-based cytogenetic study of adults with acute lymphoblastic leukemia

(2009) A. V. Moorman et al.   BLOOD

A comprehensive geriatric assessment is more effective than clinical judgment to identify elderly diffuse large cell lymphoma patients who benefit from aggressive therapy

(2009) Alessandra Tucci et al.   CANCER

Future of Cancer Incidence in the United States: Burdens Upon an Aging, Changing Nation

(2009) Benjamin D. Smith et al.   JOURNAL OF CLINICAL ONCOLOGY

Age and acute myeloid leukemia: real world data on decision to treat and outcomes from the Swedish Acute Leukemia Registry

(2008) G. Juliusson et al.   BLOOD

Time from diagnosis to treatment initiation predicts survival in younger, but not older, acute myeloid leukemia patients

(2008) M. A. Sekeres et al.   BLOOD

Improvement in survival in younger patients with acute lymphoblastic leukemia from the 1980s to the early 21st century

(2008) D. Pulte et al.   BLOOD

Clinical pharmacology of cancer therapies in older adults

(2008) A Hurria et al.   BRITISH JOURNAL OF CANCER

Tumor Regression in Cancer Patients by Very Low Doses of a T Cell-Engaging Antibody

(2008) R. Bargou et al.   SCIENCE

Treatment of Adult Acute Lymphoblastic Leukemia

(2008) Nicola Gökbuget et al.   SEMINARS IN HEMATOLOGY